How does the hormone get from its secretory gland to its target tissue? • Are steroid hormones hydrophobic or hydrophilic? How are steroid hormones transported to target tissues? ● . When the steroid hormone binds to the nuclear receptor it dimerizes and binds to HRES? What are the HRES? When the NR dimer binds to HRES how does it effect gene transcription? Serum binding protein with bound hormone Hormone, Altered cell function New protein DNA 2 HRE mRNA Plasma membrane Figure 12-30 Lehninger Principles of Biochemistry, Seventh Edition 2017 W. H. Freeman and Company Cytosol translation on ribosomes Nucleus Nuclear receptor RNA polymerase Gene transcription 3
How does the hormone get from its secretory gland to its target tissue? • Are steroid hormones hydrophobic or hydrophilic? How are steroid hormones transported to target tissues? ● . When the steroid hormone binds to the nuclear receptor it dimerizes and binds to HRES? What are the HRES? When the NR dimer binds to HRES how does it effect gene transcription? Serum binding protein with bound hormone Hormone, Altered cell function New protein DNA 2 HRE mRNA Plasma membrane Figure 12-30 Lehninger Principles of Biochemistry, Seventh Edition 2017 W. H. Freeman and Company Cytosol translation on ribosomes Nucleus Nuclear receptor RNA polymerase Gene transcription 3
Biology: The Dynamic Science (MindTap Course List)
4th Edition
ISBN:9781305389892
Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher:Peter J. Russell, Paul E. Hertz, Beverly McMillan
Chapter42: The Endocrine System
Section: Chapter Questions
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