Glucose-6-phosphate dehydrogenase (G6PD) is a critical enzyme involved in the metabolism of glucose,especially in red blood cells. Deficiencies in the enzymeare the most common human enzyme defect and occurat a high frequency in certain populations of East Africanchildren.a. Offer one hypothesis for the high incidence of G6PDmutations in East African children.b. How would you test your hypothesis further?c. Scores of different G6PD mutations affecting enzyme function have been found in human populations.Offer one explanation for the abundance of differentG6PD mutations.

Q: Approximately 50 million SNPs have thus far beenrecorded after the characterization of thousands…

A: The human genome consists of about 3 million base pairs and 23 pairs of chromosomes. Out of these,…

Q: The complete absence of one or more teeth (tooth agenesis) is a common trait in humans—indeed, more…

A: Tooth agenesis is a condition in which teeth are missing because of some genetic abnormality. The…

Q: We often speak of diseases such as phenylketonuria (PKU) andachondroplasia as having a genetic…

A: When the disorder is caused by the mutation in a gene or multiple gene or by combination of the gene…

Q: VARIATIONS IN GENE EXPRESSION In humans, the glucose-6-phosphate dehydrogenase (G6PD) gene involved…

A: Introduction Genes are the basic unit of heredity. One gene has two alleles. Each allele is…

Q: Glucose-6-phosphate dehydrogenase deficiency (G6PD) is inherited as a recessive allele of an…

A: G6PD deficiency is a genetic abnormality that occurs when an inadequate amount of…

Q: Six months pregnant, an expectant mother had a routineultrasound that showed that the limbs of the…

A: Achondroplasia is an abnormality related to bone growth that includes obstruction in the formation…

Q: Variations in Gene Expression In humans, the glucose-6-phosphate dehydrogenase (G6PD) gene involved…

A: In the Sex-linked inheritance , both X and Y chromosomes are sex chromosomes. The genes of sex…

Q: Discuss the role of mutation in the origin of genetic polymorphisms. Suppose that a genetic…

A: Mutation is the modification in the nucleotide sequence or deoxyribonucleic acid (DNA) sequence of…

Q: Albinism is characterized by the lack of a dark pigment called melanin in the hair, skin and eyes.…

A: Albinism is a genetic condition that affects the production of melanin. Melanin is the pigment that…

Q: The complete absence of one or more teeth (tooth agenesis) is a common trait in humans—indeed, more…

A: The pedigree chart indicates several generations and helps understand the inheritance pattern of a…

Q: In a study, an undergraduate student discovered a new enzyme involved in the metabolism of…

A: Enzymes are usually protein molecules which catalyzes several biochemical reactions. It works as a…

Q: If a pure line wheat plant with a colored kernel (genotype = DDEE) is crossed to plant with white…

A: Introduction: The genotype refers to the genetic material passed between generations, and the…

Q: catalyse the corresponding reactions indicated above. The recessive alleles a, b, c and d are…

A: Independent assortment is one type of genetic recombination. When chromosomes are sorted into…

Q: Considering the genetics cross and observed phenotypes pictured: a. Which genetic cross(es) led to…

A: As this is a multi part question, we are instructed to answer only 3 sub parts. Please repost the…

Q: a. Explain the difference between maternal inheritanceof organelle DNAs and maternal effect…

A: There are two types of sex chromosomes X and Y chromosomes. The autosomes are the same in both male…

Q: Describe how polymorphisms is found at 13910-C/T and 22018-G/A in the regulatory area of the lactase…

A: Lactose is the main sugar in milk, which is a disaccharide. It is hydrolyzed by intestinal lactase…

Q: The accompanying pedigree shows the pattern of transmission of two rare human phenotypes: cataract…

A: Inheritance is the process of transmitting the traits from parent to offspring. Traits of an…

Q: Bombay effect.

A: The Bombay effect is a phenomenon depicted by the H antigen, which is responsible for the expression…

Q: In retinoblastoma, a mutation in one allele of the RB1 tumorsuppressorgene can be inherited from the…

A: Retinoblastoma is a rare retinal disease that develops a malignant tumor in the retinal layers of…

Q: Duchenne muscular dystrophy is sex linked and usuallyaffects only males. Victims of the disease…

A: Duchenne muscular dystrophy is an X-linked recessive disorder. Males have an XY chromosomal pattern,…

Q: Which of the following statements describes the correlation between the genotype, phosphate…

A: Given: Need to find which statement describes the correlation between the genotype, phosphate…

Q: a. Suppose there are two genes - A and B - that specify production of the same enzyme. These two…

A: In an autosomal recessive disorder, one mutated gene is inherited from each parent. The parents each…

Q: Six months pregnant, an expectant mother had a routineultrasound that showed that the limbs of the…

A: In genetics, achondroplasia is defined as the rare type of genetic disorder related to the growth of…

Q: Phenylketonuria (PKU) is a disease that results from a recessive gene.Suppose that two unaffected…

A: Phenylketonuria (PKU) is a genetic disorder that arises due to a mutation in the PAH gene.   it is a…

Q: Hemophilia A is caused by a sex-linked recessive gene in human and in dogs. a. What proportions…

A: Thank you for the question  Answer : Hemophilia is a genetic disorder in which a persons clotting…

Q: For the first experiment ever on Drosophila mutations. Answer the following questions. a. What is…

A: Drosophila melanogaster  It is the species of fly which belongs to the family of Drosophilidae. It…

Q: people with osteogenesis imperfecta have a dominant mutation in one of the two genes that produce…

A: Mutation - Mutation is defined as the sudden change or alteration in the DNA sequence. Mutation is…

Q: a. The ABO blood groups are controlled by the alleles of a single gene. A very rare example of…

A: ABO blood types used to identify the presence of antigens. There could be the presence of one, both…

Q: See the hypothetical pathway answer the following questions. A) If an individual is homozygous for…

A: A null mutation refers to the mutation that makes an allele non-functional. The gene having the…

Q: Through GWAS explorations, scientists have identified several SNPs linked to obesity in people who…

A: Fat mass and obesity associated protein (FTO) is otherwise known as alpha-ketoglutarate-dependent…

Q: This pedigree traces the inheritance of a rare disease in humans. a. Based on this pedigree, is the…

A: Answer is given below.

Q: Phenylketonuria (PKU) is a disease that results from a recessive gene. Suppose that two unaffected…

A: Phenylketonuria (PKU) is a genetic disorder that arises due to a mutation in the PAH gene. it is a…

Q: . Considering the yellow and green pea color phenotypes studied by Gregor Mendel:a. What is the…

A: Gregor Mendel conducted hybridization experiments on garden peas and proposed the laws of…

Q: Most black bears (Ursus americanus) are black or brown in color. However, occasional white bears of…

A: As given in the question, allele that encodes for the black or brown color (A) is dominant over the…

Q: Several members of the family in the pedigree who suffered from a disease are colored in black.…

A: A pedigree represents the genetic history of a family using different lines and symbols. It displays…

Q: A certain form of sickle cell anemia is caused by an autosomal recessive allele. Assume that the…

A: Sickle cell anemia is a hereditary blood cell disorder. Homozygous dominant individuals (SS and the…

Q: Tay–Sachs disease is caused by loss-of-function mutations ina gene on chromosome 15 that encodes a…

A: Tay–Sachs disease can be defined as a hereditary condition that causes nerve cells present in the…

Q: A woman has blood type B. She had children with a man who has blood type AB. Their biological sons…

A: The ABO blood locus is controlled by the multiple alleles. The allele A and B are codominat with…

Q: Albinism occurs when cells cannot chemically synthesize pigment molecules. This occurs because the…

A: Albinism is a category of genetic illnesses in which the pigment melanin, which affects the colour…

Q: Galactosemia is a recessive human disease that istreatable by restricting lactose and glucose in the…

A: Gene: Genes are genetic material that passes from parents to progeny. The dominant allele can…

Q: (a) Which allele/s will MOST likely result in an anomalous phenotype? (b) Explain your answer in…

A: I gave you the answers below

Q: GB A GA Y Y А В G GA Y Y ВА B C D GB Y A E

A: A sex-linked trait is one where the gene for that particular trait is located on the sex chromosome…

Q: What is the Chi-squared Goodness of Fit test used to test? a. If the disease is due to…

A: The Chi-square test is used in genetics to find out whether there is a difference in observed and…

Q: The rosy (ry) gene of Drosophila encodes an enzymecalled xanthine dehydrogenase. Flies homozygous…

A: The bristle and wing phenotypes of offspring are the result of the order of ry564 and ry41 relative…

Q: In sweet peas, the synthesis of purple anthocyanin pigment in the petals is controlled by two genes,…

A: In sweet peas, the synthesis of purple anthocyanin pigment in the petals is controlled by two genes,…

Q: a) what feature of the genome is likely to be located between the two LD blocks that allows…

A: LD blocks are linkage disequilibrium blocks present in a chromosome. It is defined as an event in…

Q: In squirrels, individuals that are heterozygous for the mutant LDL receptor gene( Fa) begin to…

A: In the case mentioned above, the squirrels experience heart attacks quite early when they have both…

Q: William Jeffrey and his colleagues crossed surface-dwelling Mexican tetras that had fully developed…

A: Sonic Hedgehog : Master Gene for Embryogenesis In the days before molecular biology, embhryologists…

Mitochondrial Mutations

A mitochondrion is a cellular organelle that serves as the site for cellular respiration and energy production (ATP or Adenosine Triphosphate). It is a double-membrane-bound organelle and is only present in eukaryotic cells.