Ensure answers are clearly labelled a) & b). a) Consider the following pedigree. The solid symbols represent affected individuals. Which of the following is / are possible genotypes for IV-2 with respect to this disease? Please type 1 - 4, and indicate yes or no only for each. II III IV V 1. xAxa 2. хаҳа 3. Аa 4. A'A2 b) Genes A, B and C are on the same chromosome linked in cis (coupling) conformation. A is 23 cM from B, and B is 17 cM from C. The distance between A and C is 40 cM. The coefficient of coincidence is 0.75 for a trihybrid test cross. How many individuals with the genotype aaBbcc do you expect to see among the offspring of the cross if 1000 offspring are obtained? Please show your calculations and round your answer off to the nearest whole number. ,

Ensure answers are clearly labelled a) & b). a) Consider the following pedigree. The solid symbols represent affected individuals. Which of the following is / are possible genotypes for IV-2 with respect to this disease? Please type 1 - 4, and indicate yes or no only for each. II III IV V 1. xAxa 2. хаҳа 3. Аa 4. A'A2 b) Genes A, B and C are on the same chromosome linked in cis (coupling) conformation. A is 23 cM from B, and B is 17 cM from C. The distance between A and C is 40 cM. The coefficient of coincidence is 0.75 for a trihybrid test cross. How many individuals with the genotype aaBbcc do you expect to see among the offspring of the cross if 1000 offspring are obtained? Please show your calculations and round your answer off to the nearest whole number. ,

Name: Ensure answers are clearly labelled a) & b).a) Consider the following
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Description: Ensure answers are clearly labelled a) & b).a) Consider the following pedigree. The solid symbols represent affected individuals. Which of the following is / are possible genotypes for IV-2 with respect tothis disease? Please type 1 - 4, and indicat

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter6: Cytogenetics: Karyotypes And Chromosome Aberrations

Section: Chapter Questions

Problem 2QP: Given the karyotype shown at right, is this a male or a female? Normal or abnormal? What would the...

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Ensure answers are clearly labelled a) & b). a) Consider the following pedigree. The solid symbols represent affected individuals. Which of the following is / are possible genotypes for II-2 with respect to this disease? Please type 1 - 4, and indicate yes or no only for each. II III 1. xAxa 2. xaxa 3. Aa 4. AA2 b) Genes A, B and C are on the same chromosome linked in cis (coupling) conformation. A'is 16 cM from B, and B is 22 cM from C. The distance between A and C is 38 cM. The coefficient of coincidence is 0.55 for a trihybrid test cross. How many individuals with the genotype AabbCc do you expect to see among the offspring of the cross if 1000 offspring are obtained? Please show your calculations and round your answer off to the nearest whole number.
A child has a blood type of “B positive”. This child is known to be a heterozygote at the ABO blood type gene and also a heterozygote at the Rh blood type gene. Select all of the choices below that show possible parents of this child.a) Genotypes IA IA X IA IAb) Genotypes IA IA X IA i c) Genotypes IA i X IA id) Genotypes IA IA X IA IBe) Genotypes IA IA X IB if) Genotypes IA IA X i ig) Genotypes IA i X i ih) Genotypes IA i X IB ii) Genotypes IB IB X IB IBj) Genotypes IB IB X IB ik) Genotypes IB IB X IA il) Genotypes IB IB X i im) Genotypes IB i X IB in) Genotypes IB i X i io) Genotypes IB IB X IA IBp) Genotypes IA IA X IB IBq) Genotypes IA IB X IA IBr) Genotypes IA IB X IA is) Genotypes IA IB X IB it) Genotypes IA IB X i iu) Genotypes i i X i iv) Genotypes + + X + +w) Genotypes + + X + -x) Genotypes + + X - -y) Genotypes + - X + -z) Genotypes - - X + -a1) Genotypes - - X - -
a) What is the mode of inheritance in the following pedigree for the disease trait (autosomal dominant or recessive?) b) What are the possible genotypes for each individual in the pedigree? (Hint: You can use “A” for dominant allele and “a” for recessive allele)
A man of blood group A is being sued by a woman of blood group B for paternity. The women’s child is blood group O. A) Is this man the father of this child? Explain. B) If this man actually is the father of this child, specify the genotypes of both parents. C.) If it was impossible for this group A man to be the father of a type O child, regardless of the mother’s genotype, specify his genotype. D.) If a man was blood group AB, could he be the father of a group O child? Why/why not?
If a Mother's genotype is IAi and her Daughter's genotype is ii and the mother claims a man who is type B as the father... a) Is that possible? Explain. b) The accused man can prove that both of his parents are type AB. Is it possible for him to be type B? If so, what is his genotype? Explain. d) Does the answer in part c change the answer in part b? Explain.
1. The pedigree below shows the incidence of rare, autosomal dominant disorder called Ehlers-Danlos disease. The pedigree covers three generations of a particular family and also shows individual genotypes at a potential marker locus (M). a) Indicate the phase of all gen II and III individuals. DdM1M3 ddM2M6 II DDM3M6 ddM4M5 III DdMзM4 DdMЗМ5 DDM3M4 ddM3M5 DDM3M4 ddM5M6 DDM3M4 ddM4M6 ddM5M6 ddM5M6 b) Which, if any, of the gen III individuals are recombinants? c) Calculate the LOD score as a test of physical linkage between the marker (M) and the disease locus. d) What do you conclude about linkage between D and M?
a) A woman who is type A has a daughter who is type O. Give the genotypes of both the mother and of the daughter. b) The mother claims a man who is type B is the father. Is that possible? Explain. c) The accused man can prove that both of his parents are type AB. Is it possible for him to be type B? If so, what is his genotype? d) Does the answer in part c change the answer in part b?
A) what are the genotypes for EB27 and EB67? B) what is the relationship between the three alleles (B,br, y)? Show evidence using the pedigree
PKU is an inherited disease caused by a recessive allele. If a woman and her husband, who are both carriers (heterozygotes) for the disorder, have three children, what is the probability of each of the following? a) All three children are of normal phenotype. b) All three children have the disease. c) Any 2 of the three children have the normal phenotype.
Several genes in humans in addition to the ABO gene () give rise to recognizable antigens on the surface of the red blood cells. The Rh marker is determined by positive (R) and negative alleles () of gene R, where R is completely dominant to r. The presence of M and N surface proteins are controlled by two codominant alleles of gene L (LM and LM. For each mother-child pair, choose the father of the child from among the males in the right column. (Assume that all mothers and fathers are HH; there is no involvement of the Bombay phenotype.) Paternal genotypes maybe used once, more than once, or not at all. Each mother-child pair matches with one or more than one paternal genotype. Maternal phenotype: Child phenotype: Paternal genotype: Reset A, M, Rh(neg) O, M, Rh(pos) B, N, Rh(neg) O, N, Rh(pos) O, M, Rh(neg) A, MN, Rh(pos) A, N, Rh(pos) AB, MN, Rh(pos) B, N, Rh(pos) A, MN, Rh(neg) Genotypes of possible fathers AiLMLN rr BiLMLN RR ii LNLN rr ii LMLM rr AALMLN RR
1. The figure below shows a pedigree examining the presence of a genetic disorder across multiple generations of a family. Based off this figure, answer the following questions prompted: || IV 3 9 10 5 2 C 6 11 T 7 12 8 15 13 16 14 17 d) What is the genotype for individual #4 in this family pedigree? ||| c) Why are no family members identified as a carrier of this genetic disorder? Figure Key a) Using the figure key provided, identify which members of this family are affected by this genetic disorder in each generation. (Be sure to include sex and generation number for each individual identified). b) Is this an autosomal recessive, autosomal dominant, or sex-linked genetic disorder? Explain. Unaffected Female Unaffected Male Affected Female ||| Affected Male Female Carrier Male Carrier
a) A woman who is type A has a daughter who is type O. Give the genotypes of both the mother and of the daughter. b) The mother claims a man who is type B is the father. Is that possible?