Determine whether the following statement regarding the mechanism of the SERCA pump is TRUE (T) or FALSE (F). 1. In the E1 conformation, the two Ca2+-binding sites are exposed on the luminal side of the ER or sarcoplasmic reticulum. 2. ATP binding alone drives a conformation change from E1 to E2.

Human Physiology: From Cells to Systems (MindTap Course List)
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Determine whether the following statement regarding the mechanism of the SERCA pump is TRUE (T) or FALSE (F).

1. In the E1 conformation, the two Ca2+-binding sites are exposed on the luminal side of the ER or sarcoplasmic reticulum.

2. ATP binding alone drives a conformation change from E1 to E2.

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