Chemistry Most of the reactions in gluconeogenesis are the simple reversal of the ‘forward’ reactions used in glycolysis. However, formation of PEP in gluconeogenesis from pyruvate by pyruvate kinase is not feasible because the DG of this reaction is too unfavourable. Describe the source(s) of the energy used in gluconeogenesis to drive the production of PEP.

Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter18: Glycolysis
Section: Chapter Questions
Problem 6P: The Reactions and Meehanisms of the Leloir Pathway Write the reactions that permit galactose to be...
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Chemistry

Most of the reactions in gluconeogenesis are the simple reversal of the ‘forward’ reactions used in glycolysis. However, formation of PEP in gluconeogenesis from pyruvate by pyruvate kinase is not feasible because the DG of this reaction is too unfavourable. Describe the source(s) of the energy used in gluconeogenesis to drive the production of PEP. 

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