(c) The sedative, R-thalidomide, was once used to address symptoms of morning sickness in expectant mothers, however, when it was discovered that S- thalidomide causes deformities in infants, the use of R-thalidomide as a sedative was discontinued. With the help of a reaction mechanism, explain why enantiopure R-thalidomide can not be safely used as a sedative without affecting infants
(c) The sedative, R-thalidomide, was once used to address symptoms of morning sickness in expectant mothers, however, when it was discovered that S- thalidomide causes deformities in infants, the use of R-thalidomide as a sedative was discontinued. With the help of a reaction mechanism, explain why enantiopure R-thalidomide can not be safely used as a sedative without affecting infants
Organic Chemistry
8th Edition
ISBN:9781305580350
Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Chapter10: Alcohols
Section: Chapter Questions
Problem 10.58P
Related questions
Question
![(c) The sedative, R-thalidomide, was once used to address symptoms of morning
sickness in expectant mothers, however, when it was discovered that S-
thalidomide causes deformities in infants, the use of R-thalidomide as a sedative
was discontinued.
With the help of a reaction mechanism, explain why enantiopure R-thalidomide
can not be safely used as a sedative without affecting infants](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F99e7a993-4453-4d1c-b9a9-7ffcde301fb2%2F07b9e72e-66b5-4232-8a4b-3e0c23360197%2Fbz1ci7_processed.jpeg&w=3840&q=75)
Transcribed Image Text:(c) The sedative, R-thalidomide, was once used to address symptoms of morning
sickness in expectant mothers, however, when it was discovered that S-
thalidomide causes deformities in infants, the use of R-thalidomide as a sedative
was discontinued.
With the help of a reaction mechanism, explain why enantiopure R-thalidomide
can not be safely used as a sedative without affecting infants
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