B 110um Select one: .. The area marked A contains mostly hypoxic cells b. The area marked A probably contains cells expressing HIF1alpha e. The area marked B probably contains cells expressing HIFlalpha d. Both a and b are true

B 110um Select one: .. The area marked A contains mostly hypoxic cells b. The area marked A probably contains cells expressing HIF1alpha e. The area marked B probably contains cells expressing HIFlalpha d. Both a and b are true

Human Biology (MindTap Course List)

11th Edition

ISBN:9781305112100

Author:Cecie Starr, Beverly McMillan

Publisher:Cecie Starr, Beverly McMillan

Chapter22: Genes And Disease: Cancer

Section: Chapter Questions

Problem 5RQ

See similar textbooks

Related questions

Q: Suppose 1.5g is ordered via IV q4h starting immediately. If the drug has a half life of 4 hours,…

A: The half life of a pharmacological agent (drug) is the time taken by the drug to reach its 50%…

Q: Patients with sever ly reduced C3 levels tend to have а. Increased number of severe viral infections…

A: C3 means complement component is a protein present in the immune system. It is important for innate…

Q: Choose all the correct statments. O A person with type AB blood can receive a transfusion form a…

A: There is various blood grouping system to understand the classification of blood. The most popular…

Q: 3. Differentiate the pathology in vonwillebrand's disease from Hemophilia A, B and C.

A: Introduction Bleeding disorders are a range of disorders in which the body's blood clotting process…

Q: High serum iron appear in : a. Chronic blood loss. b. Hemolytic anemia. c. Infection. d. Pregnancy.1

A: Serum iron test is used to measure the concentration of iron in the serum. It involves the insertion…

Q: 3.[Single Choice]The diagnosis of progressive hemothorax was made by A.Repeated determination of HB…

A: Collection of blood from the space between the pleural cavity and the chest wall and is called…

Q: Ali is a 75-year-old, 62-kg (5 ft 9 in) male with S. epidermidis sepsis. His current serum…

A: Given- Serum creatinine- 1.3mg/dl Steady peak concentration-40ug/ml Steady state trough…

Q: A person with blood type A has a. anti-B antibodies in her blood plasma. b. anti-A antibodies in her…

A: Antigen are proteins present on the surface of red blood cells. Antibodies are the proteins that are…

Q: An individual who is type O can be transfused with type, red cells O a. A O b.B O.O Od.AB

A: Blood is a liquid substance which flows in the blood vessels and carry nutrients and oxygen to the…

Q: before a hematocrit can be calculated

Q: Draw the structures of the three antigens that determine the blood type in humans. i.e. draw the…

A: Blood is a connective fluid in the body made up of blood plasma and formed elements. Formed elements…

Q: 2- a) Draw the structures of the three antigens that determine the blood type in humans. i.e. draw…

A: Blood group is determined by the presence and absence of the antigen. The plasma membrane of RBCs…

Q: Lacking vitamin K could lead to excessive bleeding? A. True B. False

A: Introduction :- Bleeding (haemorrhage) into the skin (producing bruises), from the nose, from a cut,…

Q: 8. A woman has normal blood clotting but testing indicated that she is a carrier of hemophilia. Her…

A: Haemophilia is an X linked recessive disorder. Let, XH - normal X chromosome and Xh - haemophilic…

Q: Which individual is most likely to have the highest hematocrit level? a. a 10-year-old child b. a…

A: A normal range is considered to be: For men, 38.3 to 48.6 percent and for women, 35.5 to 44.9…

Q: What is the DIFFERENCE between serum and plasma? O a Serum is produced from animal blood but plasma…

A: Difference between serum and plasma

Q: During a gas explosive Musa had a 3rd degree burns. Laboratory result perform show a low plasma…

A: Full-thickness damages that penetrate the dermis and impact deeper structures are known as…

Q: 6. What leukocyte is increased in allergic reactions? 7. As the cell matures, the cell diameter…

A: Hematopoiesis is the production of all of the cellular components of blood and blood plasma…

Q: In preparying cells for karyotyping, a hypotonic solution is used in the process. What is the…

A: Cytogenetics is the science or study of chromosomes.

Q: Hematopoiesis refers to I Multipotent haematopoietic stem cells are involved in this process I. the…

A: Hematopoiesis is a process, which involves the production of all of the cellular components of the…

Q: 1. The number of white blood cells in the circulating blood is 4,300 to 10.800 per milliliter and…

A: Since you have asked multiple questions, we will answer only the first question for you. If you want…

Q: Mr Juju verbalises that he was vaccinated for corona viruses two weeks ago 1.2.1. Explain the role…

A: In this question asked about the role of antibodies following covid vaccination. In second question…

Q: Hematocrit 44% What is the correct interpretation for her result? A. Low…

A: Hematocrit is the percentage of red cells in the blood.

Q: Calculate the creatinine clearance for Lola, a 69 year old woman who weighs 66kg and has a serum…

A: Cockroft Gault equation can be used to calculate creatine clearance We will put the values in the…

Q: le with normal blood clotting, answer the following questions. a. What fraction of the female…

A: Hemophilia is usually an inherited bleeding disorder in which the blood does not clot properly. This…

Q: A person with the blood type B- would... O be missing the Rh factor (antigen D) on their red blood…

A: The blood group is encoded by the polygenic inheritance. iA, iB and i alleles encode the blood…

Q: 1. Cancer of the white blood cells is called leukemia. Like other cancers, leukemia is associated…

A: Introduction Cancer is a term used to describe a group of diseases characterised by abnormal cell…

Q: What are the acute phase proteins ? Illustrate examples .

A: Acute phase proteins are those proteins whose plasma concentrations increases (known as positive…

Q: Why is haptoglobin depletion the most sensitive indicator of hemolysis among plasma proteins?…

A: Haptoglobin is a protein encoded by the HP gene. It is mainly synthesized in the hepatocytes. In the…

Q: 7. Hematopoiesis refers to I Multipotent haematopoietic stem cells are involved in this process II.…

A: Hematopoiesis is the production of all types of cellular components of blood and blood plasma in the…

Q: 2. A woman who is a carrier for hemophilia has chil a) What is the probability that their children…

A: Haemophilia is a bleeding disorder in which the blood does not clot normally. The mutant gene for…

Q: Describe the different types of familial hypolipoproteinemia in terms of electrophoretic mobility…

A: Familial hypobetalipoproteinemia (FHBL) is a disorder of the body that impairs capacity to absorb…

Q: 6) a) Provide using your best reasoning skills an explanation as to why Rh incompatibility is so…

A: The ABO blood group system is a classification of human blood types according to the presence or…

Q: 7. Hematopoiesis refers to I Multipotent haematopoietic stem cells are involved in this process II.…

A: Bone marrow is the spongy and viscous tissue that fills the inside our bones. It is the place where…

Q: The cytoplasm of these cells have large dark granules that contain heparin and histamine: a.…

A: Blood is a continually flowing liquid giving the body nourishment, oxygen, and waste expulsion.…

Q: 3. Complete the following table regarding the laboratory test results associated with various Factor…

A: Blood coagulation helps in the formation of a plug or fibrin meshwork at the site of injury or wound…

Q: If you tested a sample of blood and it clumped in serum A, but did not clump in serum B, or the Rh…

A: Blood typing is commonly done to detect the type of blood group present in the person. In humans,…

Concept explainers

Clinical Pharmacology

Pharmacology is a discipline of medicine that studies how medications interact with the systems and processes of living organisms, focusing on drug action mechanisms as well as therapeutic and other purposes.

Question

In the diagram, the center line indicates a blood vessel supplying nutrients to a tumor
110um
Select one:
. The area marked A contains mostly hypoxic cells
b. The area marked A probably contains cells expressing HIFTalpha
e. The area marked B probably contains cells expressing HIF1alpha
d. Both a and b are true

Expert Solution

This question has been solved!

Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.

This is a popular solution!

SEE SOLUTION Check out a sample Q&A here

Step 1

VIEW

Step 2

VIEW

Trending now

This is a popular solution!

Step by step

Solved in 2 steps

SEE SOLUTION Check out a sample Q&A here

Knowledge Booster

Learn more about

Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.

Similar questions

A 42-year-old woman comes to the physician for a follow-up examination after two separate Pap smears have shown dysplastic epithelial cells. Results of a molecular diagnostic test show DNA that encodes high-risk versions of the human papillomavirus E6 and E7 proteins. The viral E6 protein binds to the cellular p53 tumor suppressor gene, causing it to be degraded. Which of the following best describes the mechanism by which the E6 protein causes cervical cancer? (A) Arrests the cell cycle (B) Enhances tissue invasion and metastasis (C) Inhibits telomerase expression (D) Prevents apoptosis (E) Sustains angiogenesis
Which of the following statements are correct about the ability of cancer cells to form a secondary tumor at a site distant from the primary tumor (select all that apply)? A. Is possessed by majority of cells in a tumor B. Most micrometasases fail to become secondary tumor C. Usually occurs prior to establishment of micrometatstases D. Ability is acquired along with ability to move through circulation E. Is often acquired after micrometastases have been estabilished
Pick one initial of TNM cancer staging and identify what the different stages are and what they mean.
The Bcl-2 protein was initially discovered via its ability to contribute to progression of B-cells to a cancerous "lymphoma" phenotype. 1) Define the mutation that was associated with the change in Bcl-2 in these cells. 2) Is Bcl-2 an oncogene or a tumor suppressor gene? 3) Define the role of Bcl-2 in normal cellular function and how this changed in Bcl-2 associated lymphoma.
14. Reading the following statements about TNM staging of tumors, the wrong one is: "T" refers to the depth of local invasion of the tumor "N" refers to the peripheral lymph node metastasis "M" refers to the distal transfer situation TNM staging criteria for all tumors are consistent TNM staging is the basis for the development of clinical surgical treatment plan
Name the six fundamental properties of malignant tumours. Which of these properties are amenable to study in a cell culture model of cancer and why?
1. Describe & explain the pathophysiology of cancer based on the diagram. Reference: https://www.onlinebiologynotes.com/cancer-etiology-pathophysiology-types-diagnosis-and- treatment/ Acquired (environmental) DNA damaging agents: • chemical • radiation viruses Activation of growth- promoting oncogenes NORMAL CELL DNA Damage Failure of DNA repair Mutations in the genome of somatic cells Alteration of genes that regulate apoptosis Malignant neoplasm / Successful DNA repair CANCER Inherited mutations: • Genes affecting DNA repair • Genes affecting cell growth Expression of altered gene products and loss of regulatory gene products Inactivation of cancer suppresor genes Clonal expansion Additional mutations (progression) T Heterogeneity
Which of the following factors contributes to angiogenesis as a result of a tumor growth? Select all that apply: a. Increasing tumor's access to oxygen and nutrients b. Increasing tumor's ability for growth, invasion, and metastasis c. Increasing expression of proto-oncogenes for cancer cells d. Increasing expression of tumor-suppressor genes for cancer cells
certain tumor types secrete FSH-can you elaborate on this malignancy/tumor type? Can you please help me with this question? Thank you in advance!
Explain Three mechanisms for viral induction of cancer.
Which of the following statements are correct about tumors and metastasis (select all that apply)? A. The majority of cancer deaths are due to primary tumor B. Loss of basement membrane by tumor mass is strong predictor of metastasis potential C. The tissue stroma contributes to whether a tumor cell will metastasize D. The majority of life threatening tumors occur in epithelial tissues E. The tendency of a primary tumor to metastasize is similar across different tissue types
Out of these 8 hallmarks ( sustaining proliferative signaling, evading growth suppressors, resisting cell death, enabling replicative immortality, inducing angiogenesis, activating invasion and metastasis, deregulating cellular energetics and metabolism, and avoiding immune destruction). Rank them from least important to most for cancer development. Explain in 2-3 sentences how.