4 Assume that the complete combustion of one mole of glucose to carbon dioxide and water liberates 2870 kJ/mol(AG° = -2870 kJ/mol).If one contraction cycle in muscle requires 63 kJ, and the energy from the combustion of glucose is converted with an efficiencyof 35% to contraction, how many contraction cycles could theoretically be fueled by the complete combustion of one mole ofglucose? Round your answer to the nearest whole number.cycles per mole glucose =

Given:Complete combustion of one mole of glucose liberates 2870 kJ.ΔG° = -2870 kJ/mol Efficiency of…

Answered: Assume that the complete combustion of…

Biochemistry

6th Edition

ISBN:9781305577206

Author:Reginald H. Garrett, Charles M. Grisham

Publisher:Reginald H. Garrett, Charles M. Grisham

Chapter27: Metabolic Integration And Organ Specialization

Section: Chapter Questions

Problem 3P

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Assume that the complete combustion of one mole of glucose to carbon dioxide and water liberates 2870 kJ/mol (AGo' = -2870 kJ/mol). If one contraction cycle in muscle requires 67 kJ, and the energy from the combustion of glucose is converted with an efficiency of 35% to contraction, how many contraction cycles could theoretically be fueled by the complete combustion of one mole of glucose? Round your answer to the nearest whole number. суycles per mole glucose
In active muscle cells, the pO2 is about 10 torr at the cell surface and 1 torr at the mitochondria(the organelles where oxidative metabolism occurs). Calculate the percentage of bound oxygentransported to the mitochondria of muscle cells by myoglobin (KD = 2 torr).
Twenty-three milligrams of glucose were eaten by the bacteria Sanacoccus pumasareus. Calculate the hypothetical amount of ATP your patient can generate under aerobic respiration with this amount of glucose. (Note: Glucose MW-180.16 g/mole; 1 mole= 6.02 x 1023 molecules (Avogadro's number)). 2.8 x 10^24 ATPs 02.9 x 10^21 ATPs 028 x 10-21 ATP5 029 x 10 24 ATPS Lacks information, cannot be determined
a) (1) Calculate the physiological AG (not AG.) for the reaction: Phosphocreatine + ADP - creatine + ATP Given; Phosphocreatine + H;0 - creatine + Pi ADP + Pi → ATP + H;0 AG.' -43 kJ/mol AG.- +30.5 kJ/mol at 25°C as it occurs in the cytosol of neurons, in which phosphocreatine is present at 4.7 mM, creatine at 1.0 mM, ADP at 0.20 mM, and ATP at 2.6 mM. (R = 8.315 JK-' mol-) (ii) Caleulate the free energy change at standard conditions for the following reaction: Acetaldehyde + NADH + H* + Ethanol + NAD* The half- reactions are: Acetaldehyde + 2H + 2e + Ethanol E°- - 0.20V NAD-+ 2H- + 2e ++ NADH + H- E=-0.32V (F= 96.485 kJ/V/mol)
Intracellular concentrations in resting muscle are as follows: fructose- 6-phosphate, 1.0 mM; fructose-1,6-bisphosphate, 10 mM; AMP, 0.1 mM; ADP, 0.5 mM; ATP, 5 mM; and P, 10 mM. Is the phosphofructokinase reac- tion in muscle more or less exergonic than under standard conditions? By how much?
A researcher purifies a mutant version of the glucokinase enzyme. She combines the purified glucokinase with glucose and ATP to produce glucose 6-phosphate. She records the initial velocity (V) of glucose 6-phosphate production at various substrate concentrations ([S]). She determines a Michaelis-Menten constant (Km) of 6.2 mM for the mutant enzyme. [S] (mM) µmol min 5 1.03 10 1.42 50 2.05 100 2.17 Calculate the maximum velocity (Vmax) of the mutant glucokinase to one decimal place using the Michaelis-Menten equation. umol Vmax min
Consider the following phosphoryl group transfer reaction which is the first step in glucose catabolism by glycolysis: Glucose + ATP + Glucose 6-phosphate + ADP The AG for the reaction is -16.7 kJ/mol. (R= 8.314 J/(K. mol) (a) Calculate Keq for the reaction at 25°C (b) What is the ratio of [Glucose 6-phosphate] to [Glucose] if the ratio of [ADP] to [ATP] is 10?
What is the free energy change for generating the electrical imbalance of protons in respiring mitochondria in culture, where Δψ is 150 mV? (Express your answer in kJ/mol using 3 significant figures.)
Calculate the actual, physiological ΔG for the reaction at 37 °C, as it occurs in the cytosol of neurons, with phosphocreatine at 4.7 mM, creatine at 1.0 mM, ADP at 0.73 mM, and ATP at 2.6 mM.
Calculate all the glucose data into cmol. What is the number of cmol glucose at timepont 10.42 (19.65 g/L)?
Walking consumes approximately 100 kcal/mi. In the hydrolysis of ATP (ATP → ADP + Pi), the reaction that drives muscle contraction, ΔG°′ is −7.3 kcal/mol (−30.5 kJ/mol). Calculate how many grams of ATP must be produced to walk a mile. ATP synthesis is coupled to the oxidation of glucose (ΔG°′ = −686 kcal/mol). How many grams of glucose are actually metabolized to produce this amount of ATP? (Assume that only glucose oxidation is used to generate ATP and that 40% of the energy generated from this process is used to phosphorylate ADP. The gram molecular weight of glucose is 180 g and that of ATP is 507 g.)
The complete combustion of palmitate and glucose yields 9781 kJ ∙ mol−1 and 2850 kJ ∙ mol−1 of free energy, respectively. Compare these values to the free energy (as ATP) obtained though catabolism of palmitate and glucose under standard conditions. Which process is more efficient?

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