After exhalation of carbon dioxide, His 146 becomes in O Protonated; Increased O Deprotonated; Decreased oxygen binding affinity by hemoglobin. Deprotonated; Increased Protonated; Decreased resulting
Q: Concept map: construct a map of gas transport using the following terms. alveoli, arterial blood,…
A: Q.Ans:- These all terms belong to a single physiology known as Respiration.Respiration is a term…
Q: Many reactions in metabolism are thermodynamically unfavorable (ie-the reaction DOES NOT favor the…
A: The thermodynamically unfavorable reaction where ∆G°>0 is driven in metabolism by coupling with…
Q: Show the calculation for the preparation of 0.01%, 0.001%, 0.0001%, 0.00001% standard DNA solutions…
A: A liquid combination containing DNA molecules is called a DNA solution. It is frequently employed in…
Q: The two sides of the DNA double helix are connected by pairs of bases (adenine, thymine, cytosine,…
A: Consider 2 charges q1 and q2, the force between 2 charges is given by:Where,K is a constant (9×109…
Q: What is the hydrogen bonding pattern within an alpha helix? a. Lone pair on C=O of residue i to…
A: We have to determine the hydrogen bonding pattern within an alpha helix
Q: = An Fab fragment binds to lysozyme with a dissociation constant of Ka 10-¹1 M. A 1 nM (10-⁹ M)…
A: we can use the equation for the fractional saturation (Y):Y=[F]/Kd+[F]Given:Kd=10−11M[L]=10−9M
Q: 1 a- What is the approximate length of a DNA molecule (in the B form) containing 10,000 base pairs?…
A: The approximate length of a DNA molecule containing 10,000 base pairs can be calculated by using the…
Q: Draw a diagram of a water molecule. Show all valence electrons, lone pairs, molecular geometry, and…
A: Molecules are made up of two or more than two atoms.We have been asked to draw a diagram of water…
Q: Substrate concentration, [S], has units of micromolar, µM. Enzyme velocity, V₁, has units of…
A: For a one-substrate enzyme-catalyzed reaction, the Michaelis-Menton equation shows the quantitative…
Q: Information about poison
A: Poisons are toxic substances or chemicals which interfere the biological process and lead to failing…
Q: Consider the following isomerization reactions of some simple sugars and values for their standard…
A: Details
Q: Name Lysine Arginine Histidine Aspartate Glutamate Structure 1-Let Abbr 3-Let Abbr Class Special…
A: Amino acids are organic compounds that form the building blocks of proteins in cells. The structure…
Q: QUESTION 32 Which pair has similar chemical properties? O ¹H and 22 Na O 12C and 28gi O160 and 32
A: Atoms are the building blocks of matter, and the behavior of atoms in chemical reactions is…
Q: Suppose the concentration of glucose inside a cell is 0.5 mM and the cell is suspended in a glucose…
A: Details
Q: draw the hydrogen bonds that could form between water molecules and the appropriate regions of…
A: An amino acid is a carboxylic acid with an amino group and the building block of proteins and when…
Q: Question 23 Imagine that for the reaction AB the equilibrium constant is 16, and that for the…
A: To determine ΔG for the reaction A ⇌ C, we can utilize the equilibrium constants (K) and the Gibbs…
Q: xplain the structure and components of a typical URI. Provide examples of common URI schemes.
A: A URI (Uniform Resource Identifier) is a string of characters that uniquely identifies a resource…
Q: Determine whether each of the examples or phrases describes an essential amino acid, a nonessential…
A: Amino acids are the building blocks of proteins, which are essential molecules in living organisms.…
Q: Which solution conditions would be best used for eluting a transcription factor from a DNA affinity…
A: We need to identify the solution conditions used for eluting a transcription factor from a DNA…
Q: A water molecule has polar O-H bonds that result in regions of partial positive charge (hydrogen…
A: Ion dipole interaction is defined as the force of interaction between charged ions and polar…
Q: The OH group of the serine side chain (R-OH) can undergo dissociation to form R-O- and H+. However,…
A: The proteins are constituted of amino acids linked via peptide linkages.The side chains of amino…
Q: to use the pH simulator to answer the question: . Select the Macro setting on the simulator…
A: Go to the pH simulator homepageOpt for the "Macro" mode on the simulator.Find the green pH meter and…
Q: Determine whether each of the examples or phrases describes an essential amino acid, a nonessential…
A: Amino acids are biomolecules that have an amino group and a carboxyl group linked to the same carbon…
Q: 2. Amino Acid Stereochemistry. Hypothetical Situation: A novel amino acid is isolated from a…
A: Amino acids are biomolecules that have an amino group, a carboxyl group and a chemically diverse…
Q: 3) After watching the video convert the monosaccharides from a Fischer to a Haworth Projection. c)…
A: Fischer and Haworth ProjectionsFischer and Haworth projections are two ways of representing the…
Q: A lysine is on the surface of a protein near an arginine, how does this alter pKa of lysine
A: The pKa of an amino acid's side chain determines whether it is protonated (+) or deprotonated (-)…
Q: 10. In an abnormal hemoglobin variant known as Hemoglobin-Kariya, the lysine residues at position 40…
A: Since you have posted multiple questions, we will provide the solution only to the first question as…
Q: 8. Draw a diagram to illustrate how hemoglobin is organized as a dimer of dimers (label the…
A: Hemoglobin is a protein found in red blood cells. In addition to carrying oxygen from the lungs to…
Q: RNase is an enzyme that cleaves the P-05 bond in RNA. It has two His residues in the active site.…
A: RNAse enzymes catalyse the breakdown of RNA molecules, which is essential for the cellular…
Q: Why is having flexible and unstructured regions of a protein important for the function of the…
A: Proteins are polypeptide structures made up of one or more extended chains of residues from the…
Q: Place each charge form of alanine under the pH condition where it would be the predominant form. The…
A: Alanine is a nonpolar amino acid. Amino acids are biomolecules that have an amino group, a carboxyl…
Q: Serine and threonine can both be directly deaminated during amino acid metabolism. What else do…
A: The building components of proteins are amino acids. They are organic compounds made composed of a…
Q: Write if TRUE/FALSE. mRNA splicing takes place in bacteria. In eukaryotes, replication and…
A: FALSE. Explanation:mRNA splicing does not take place in bacteria. mRNA splicing is a process that…
Q: You're examining an amino acid at position 3 in an alpha helix. Without knowing the specific amino…
A: Amino acids are the building blocks of proteins and play essential roles in various biological…
Q: Aberrant signaling through the EGF receptor signal transduction pathway drives many forms of breast…
A: Cell signaling is mediated by a ligand (usually a hormone but could be other molecules too) binding…
Q: If, in addition to the constraints on glucose concentration listed previously, we have in the liver…
A: To determine the theoretical concentration of glucose-6-phosphate at equilibrium in a liver cell…
Q: The hydrolysis of phosphate bonds provides the chemical energy to drive reactions in the cell. The…
A: Gibbs free energy of hydrolysis of creatine phosphate to creatine isΔG°= -43kJ/molThis implies, its…
Q: 7. A protein has a molecular mass of 400 kDa when measured by gel filtration. When subjected to gel…
A: As we know that the sodium dodecyl (SDS) sulfate is considered as the denaturing agent, which helps…
Q: The amino acid sequence of a small protein is MSRLASKNLIRSDHAGGLLQATYSAVSSIKNTMSFGAWSNAALNDSRDA.…
A: MHC (Major Histocompatibility Complex) are molecules responsible for presenting pathogenic peptides…
Q: What are the roles of sodium dodecyl sulfate (SDS) in two-dimensional electrophoresis? to cause…
A: Two-dimensional gel electrophoresis (2-DE) is an important technique in proteomics work.It is used…
Q: calculate the pI for tripeptide R-H-D
A: The pH of a solution at which a protein's net charge equals zero is called the isoelectric point…
Q: This is a portion of the periodic table of elements. What is the atomic mass of arsenic (As)? 3 Li…
A: Molecular mass is the total mass of a compound. It is equal to the sum of the atomic masses or mass…
Q: 10 mL of 1.8 M acetic acid (CH3COOH) is titrated with 1.0 M sodium hydroxide (NaOH). The titration…
A:
Q: Choose any/all that apply to protein synthesis. Ribosomes aid in the formation of peptide bonds…
A: As per the central dogma of molecular biology, genetic information for protein synthesis is stored…
Q: Which one statement below is true about the metabolism of rizatriptan? N N-N ZI rizatriptan MaxaltⓇ…
A: 3.It is a prodrug that is activated by esterases.Rizatriptan is indeed a prodrug, which means it is…
Q: Consider the hypothetical serine protease, which shows the specificity pockets. The S₁ pocket has a…
A: Enzymes are biological catalysts that increasethe rate of biochemical reactions.Most enzymes are…
Q: Put these three molecules in the order of most oxidized to least oxidized. нн нс-с-н нн H > > 0=…
A: In chemistry, the concept of oxidation state plays a crucial role in assessing the degree of…
Q: Determine how many domains and list the residues in each domains (ei. 1-230, 1-120) Vertebrate Ca…
A: The following table explains the answer.Protein-4 VCA( vertebrate Ca 2+ dependent cell adhesion…
Q: What are the key considerations in designing child-resistant packaging for pharmaceuticals and…
A: Child-resistant packaging is made to be inaccessible to kids while still being usable by adults.…
Q: Suppose that you are working with an enzyme that has an ionizable active site residue with a pk of…
A: First let's name the curves as shown below, so that we can identify each of them using these…
Trending now
This is a popular solution!
Step by step
Solved in 3 steps
- Among the given statements. which ones are true for hemoglobin? Select the correct response(S). It has ferrous cation that is coordinated by the electrophilic N atoms of the porphyrin ring. It has 4 sub-units with each sub-unit binding an oxygen molecule with the same efficiency. It has 4 sub-units with each sub-unit binding an oxygen molecule in an increasing efficiency. It has ferric cation that is coordinated by the electrophilic N atoms of the porphyrin ring. It has 4 sub-units with each sub-unit binding an oxygen molecule in a decreasing efficiency. It has ferric cation that is coordinated by the nucleophilic N atoms of the porphyrin ring. It has 4 sub-units with each sub-unit binding an oxygen molecule in a fluctuating efficiency.It has ferrous cation that is coordinated by the nucleophilic N atoms of the porphyrin ring.Allosteric inhibitors of hemoglobin will decrease enzyme activity (oxygen binding) through which of the following mechanisms? Binding the enzyme in "T" conformation and displacing an activator Binding the enzyme and enhancing the Vmax Binding the enzyme, and keeping it in the "R" conformation Binding the enzyme, and keeping it in the "T" conformationHemoglobin molecules exposed to high levels of glucose areconverted to glycated products. The most common, referred to as hemoglobin A1C (HbA1C), contains a b-chain glycatedadduct. Because red blood cells last about 3 months, HbA1Cconcentration is a useful measure of a patient’s blood sugarcontrol. In general terms, describe why and how HbA1Cforms.
- 2,3 BPG is an allosteric effector that decrease haemoglobin affinity for oxygen by stabilizing the T-state of deoxyhaemoglobin. This lead to the release of oxygen to cells and body tissues for use. H atom and CO2 are also allosteric effector and can do same. How?A person was found to have very low levels of functional beta globin mRNA and therefore very low levels of the beta globin protein. What problems would this cause for assembling functional haemoglobin molecules?Diagram the Embden-Meyerhof anaerobic glycolytic pathway (EMP) in the red blood cell (RBC), highlighting adenosine triphosphate (ATP) consumption and generation.
- O, saturation curve is shown beloww for hemoglobin at various pHs. Detail this Bohr effect from the molecular perspective. Be sure to include discussion of what causes this (i.e. specific amino acids), why the curves are right shifted with decreasing pH, and why this is logical in delivery of 02 to areas of higher demand. 100 Myoglobin 80- pH 7.6 60 pH 7.4 pll 7.2 40- pH 7.0 pH 6.8 20- Venous 0- 0. 20 10 60 80 Percent saturationHemophilia B, an X-linked genetic disorder which highly affects males, is a condition in which levels of Factor VIII are significantly decreased. Please describe the physiologic pathway which utilizes Factor VIII and describe the consequences of missing this factor from a physiologic perspective.Pentose phosphate pathway and hemolytic anemia. Explain the relationship.
- If a person lacks the enzyme necessary for BPG synthesis, does he orshe exhibit anemia (a lower-than-normal number of red blood cells) orerythrocytosis (a higher-than-normal number of red blood cells)? Explain.The primary allosteric regulator of hemoglobin oxygen affinity is ( ) and functions by stabilizing the ( ) state of enzyme.A researcher, in a study involving acid-base properties of RBC's notices the resistance of change in pH, when a small amount of acid or base is added to it. Buffering action of hemoglobin in RBCS is most likely attributed to presence of which of the following factors in the globin chains? Alpha helical structures В Beta pleated sheets C Ferric state of iron D Ferrous state of iron E Histidine residues
