Activity #2: Flow chart to diagram possible fetal cell/maternal NK and fetal cell/maternal CD8+T cell interactions Use your knowledge regarding the interaction of NK cell receptors with MHC molecules vs. CD8+ T cell receptors with MHC molecules to hypothesize how these interactions may affect pregnancy outcomes. Abbreviations used: FC = fetal cell FC + DNK HLA-G/KIR (use twice) dNK decidual (maternal) NK cell FC survive CTLS activated FC + dT loss of fetus (use twice) dT=decidual (maternal) CD8+T cell survival of fetus (use twice) dNK kill FC HLA-C/TCR (use twice)

Human Physiology: From Cells to Systems (MindTap Course List)
9th Edition
ISBN:9781285866932
Author:Lauralee Sherwood
Publisher:Lauralee Sherwood
Chapter12: Body Defenses
Section: Chapter Questions
Problem 15RE
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Activity #2: Flow chart to diagram possible fetal cell/maternal NK and fetal cell/maternal CD8+T cell interactions
Use your knowledge regarding the interaction of NK cell receptors with MHC molecules vs. CD8+ T cell receptors with
MHC molecules to hypothesize how these interactions may affect pregnancy outcomes.
Abbreviations used:
FC = fetal cell
FC + DNK
HLA-G/KIR (use twice)
+
dNK = decidual (maternal) NK cell
FC survive
dT=decidual (maternal) CD8+T cell
survival of fetus (use twice)
CTLS activated FC + dT loss of fetus (use twice)
CHI
10-1
dNK kill FC
HLA-C/TCR (use twice)
HH
H-1
Transcribed Image Text:Activity #2: Flow chart to diagram possible fetal cell/maternal NK and fetal cell/maternal CD8+T cell interactions Use your knowledge regarding the interaction of NK cell receptors with MHC molecules vs. CD8+ T cell receptors with MHC molecules to hypothesize how these interactions may affect pregnancy outcomes. Abbreviations used: FC = fetal cell FC + DNK HLA-G/KIR (use twice) + dNK = decidual (maternal) NK cell FC survive dT=decidual (maternal) CD8+T cell survival of fetus (use twice) CTLS activated FC + dT loss of fetus (use twice) CHI 10-1 dNK kill FC HLA-C/TCR (use twice) HH H-1
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