A 35 year old woman begins therapy with a drug( 50 mg twice daily) that has a volume distribution of 70L and an elimination half life of 2 days. According to first order kineticds, the average drug concentration will reach 75% of the average steady state blood concentration after how many days (A) 2 (B) 4 (C) 6 (D) 8 (E) 10
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A 35 year old woman begins therapy with a drug( 50 mg twice daily) that has a volume distribution of 70L and an elimination half life of 2 days. According to first order kineticds, the average drug concentration will reach 75% of the average steady state blood concentration after how many days
(A) 2
(B) 4
(C) 6
(D) 8
(E) 10
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- The peak plasma concentration achieved after the first IV dose of drug X is 25 mg/L. The drug’s half-life is 3.5 hours, and it is administered every 12 hours. What will be the peak plasma concentration at steady state?The plasma concentration of a drug is 50 mg/L and is decreasing in first-order fashion with a half-life of 12 hours. Approximately how may hours will it take for the blood concentration to fall to a desired range of 10-15 mg/L? (A) 12 (B) 24 (C) 36 (D) 48 (E) 50The initial plasma concentration of a drug given iv at 8:00am is 210 mg/ml. If the half life of the drug is 6 hours, what will the plasma concentration be at 7:00pm that same day?
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