The initial plasma concentration of a drug given iv at 8:00am is 210 mg/ml. If the half life of the drug is 6 hours, what will the plasma concentration be at 7:00pm that same day?
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The initial plasma concentration of a drug given iv at 8:00am is 210 mg/ml. If the half life of the drug is 6 hours, what will the plasma concentration be at 7:00pm that same day?
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- The peak plasma concentration achieved after the first IV dose of drug X is 25 mg/L. The drug’s half-life is 3.5 hours, and it is administered every 12 hours. What will be the peak plasma concentration at steady state?The nurse is preparing to give Acetaminophen to a 5year old girl weighing 20 kg. The doctor has ordered Acetaminophen 240mg PO qehr PRN pain. the safe dose range for acetaminophen is 10-15 MG/KG/dose. What is the low safe amount per dose? [1] What is the high safe amount per dose? (2) is this dose safe to give? (3]Mrs B presents you with a prescription for warfarin tablets 1 mg. The directions are to take 6 mg at 6pm that evening, followed by alternating daily doses of 4 mg and then 3 mg (as long as her INR remains within the recommended range). What is the exact number of warfarin 1 mg tablets required for a 28 day supply assuming her INR remains in range?
- The medication order for a patient is 150 mL of drug A over 2.0 hours with a drop factor of 12 gtt/mL. What is the flow rate in drops/min?The order is for 0.35 mg of epinephrine stat; the drug is available as an ampule with the concentration labeled as 1:1000 (weight in grams: volume in mL). How much volume should be administered to the patient per dose? 1) 0.035 mL 2) 0.35 mL 3) 3.5 mL 4) 35 mL100 mg dose of Drug X is administered via IV at 7 hours, blood drug concentration is 5 mcg/mL Half-life of the Drug X is 5 hours A. Find the blood concentration after 6 hours if the dose is 1g (should be between 50.39 and 61.6) B. Minimum effective concentration is 2 mcg/mL. IF the first dose was 100mg of Drug X, how many hours after the dose would reach to 2mcg/mL. (When should the 2nd dose be given). (should be between 12.06 and 14.74)
- A patient, whose weight is 80.5 kg and height is 63 inches, is to receive dacarbazine in 250 mL 5% dextrose injection over 30 to 60 minutes. Dacarbazine is available as 200 mg/vial reconstituted to 10 mg/mL. How many mL will be needed to add to the IV bag?n 10-kg infant requires a continuous infusion of a drug to run at 1 mL/hr to deliver 3 mcg of drug/kg/min. Calculate the milligrams of drug that must be added to a 100-mL IV infusion solution.A 160lb patient disagnosed with supraventricular tachycardia is to receive verapamil 5mg IV over 2 minutes. The drug is available in 4mL vials containing 2.5mg/mL. How many mL will you administer?
- A prescription order calls for 1.25 g of vancomycin in 500 mL of NS (0.9%/100mL). After reconstitution vancomycin injection is available in a strength of 50 mg/mL. How many mL of vancomycin injection should be drawn up to prepare this prescription?From an economic point of view, the consultancy firm wanted to calculate the price a patient would need to pay for the full treatment. The cost of each vial of the drug ‘A’ is $450.50 dollar where it contains 30 mg. The usual dose of drug administered is 145 mg once every 2 weeks, during a 12-week period to a patient weighing 190 lb and a height of 6 ft 2 inch. Calculate the cost for the full treatment for the above patient.The client was ordered Oral Phenergan 0.1g, TDS (three times a day). The pharmacy has dispensed Phenergan 25mg tablets. How many tablets will you administer? What dose of Phenergan will this client receive in 24 hours?