8. Which of the following takes place due to phosphorylation of isocitrate dehydrogenase? a) Inhibits the binding of citrate at active site b) Degrades the enzyme c) Enhances the substrate-binding affinity d) No reaction

8. Which of the following takes place due to phosphorylation of isocitrate dehydrogenase? a) Inhibits the binding of citrate at active site b) Degrades the enzyme c) Enhances the substrate-binding affinity d) No reaction

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

See similar textbooks

Related questions

Q: The DNA and associated proteins of a eukaryotic chromosome are called Chromatin Chromatosome…

A: Eukaryotic chromosomes are made up of DNA that is tightly coiled around histone protein clusters.…

Q: Illustrate the biosynthetic pathway of resin 2. Give 5 industrial uses of resins

A: Resins : Resins are the amorphous products on complex chemical nature. These are usually…

Q: The residual end of a pre-mRNA transcript is digested by the following enzyme

A: Transcription is the process of formation of pre-mRNA (precursor mRNA) (heterogenous mRNA) from the…

Q: As you have seen, the protein assay relies upon the ability of proteins to bind the dye. Some…

A: Proteins are made up of amino acids attached together via peptide bonds. Proteins are composed of…

Q: Polymerase chain reaction cannot amplify complete circular plasmids. True False

A: Polymerase chain reaction or PCR is a technique which is used to amplify a sample of DNA and is one…

Q: (d) Identify a wax from the list of compounds shown. ____________ (e) Identify a diglyceride from…

A: The three principal categories of lipids are phospholipids , sterols, and triglycerides.

Q: Rf Sample values A 0.21 В 0.39 C 0.33 0.27 Four amino acid samples were subjected to a normal-phase…

A: Normal phase chromatography is a type of adsorption chromatography which is used for analysis of…

Q: Answer the ff. questions: 1. What factors influence the metabolic rate of citrate in the…

A: The acetyl group of acetyl CoA is bonded to a four-carbon oxaloacetate molecules to generate a…

Q: Explain in detail the role of biotechnology in production of baker’s yeast.

A: For millennia, humans have used the metabolic activity of yeasts in baking and brewing. The creation…

Q: A buffer can protect against changes in pH when hydrogen ion or hydroxide ion is added to a reaction…

A: Buffer solution is two types, Acidic buffer - this is composed of a weak acid and it's conjugate…

Q: (a) Draw the condensed structural formula, and give the name and abbreviation for the dipeptide…

A: Dipeptide is the structure formed by two aminoacids with a single Peptide bond. Anomeric carbon is…

Q: TRUE OR FALSE: Please answer each item. Hormones, such as testosterone, estradiol and progesterone…

A: The most abundant lipid in the membrane is a phospholipid. Ruff degradation is a functionally…

Q: running the reaction at 83 °C cooling the reaction to 11 °C changing the pH to 5.4 Increase reaction…

A: The rate of an enzyme catalyzed reaction depends on various factors like temperature and pH of the…

Q: Is proteus vulgaris positive or negative in lia test? Why?

A: Proteus vulgaris is a gram negative bacteria that test positive for indole and catalase production.…

Q: Do enzymes act better under acidic or alkaline pHs? Explain your answer

A: Enzymes are biological catalysts that are proteins. Chemical reactions are sped up with catalysts.…

Q: The concentration of your RNA solution is 1500 ng/μl. How much RNA solution do you need to use when…

A: The concentration of RNA in solution can be determined by measuring absorbance at 360 nm.

Q: Glucose is a polar molecule. Would you predict that the amino acids of the enzyme hexokinase in the…

A: hexokinase catalyzes the transfer of the phosporyl group. The enzyme undergoes induced-fit…

Q: 9. L-lactate dehydrogenase: L-lactic acid:: Salivary a-amylase: a) D-aminoacid b) L-aminoacid c) a-…

A: All biological chemical reaction reactions in living beings are controlled by enzymes. If enzymes…

Q: `NH HO `NH2 ОН ОН

A: Nucleoside contains a nitrogenous base and a ribose or deoxyribose sugar molecule.

Q: Match the items on the diagram with the correct term below. 3' 5' 5 D 8 Activate W DNA Replication…

A: DNA replication is the particular process by which a specific molecule of DNA is being duplicated.…

Q: Discuss models for how amyloid fibrils form from unfolded or misfolded proteins and for how the cell…

A: Misfolded proteins result in many degenerative diseases and this often occurs due to several…

Q: (b) Provide the mechanism of Merrifield Resin synthesis taking any tripeptide. Explain one method of…

A: The Merrifield Resin is a cross-linked polystyrene resin that carries a chloromethyl functional…

Q: 4. Draw the number of fragments as well as their sizes as they would migrate on the electrophoresis…

A: Sal1 is a restriction endonuclease i.e it cleaves DNA at the recognition sequence 5'-G/TCGAC-3'…

Q: Assume you were given a mixture consisting of one molecule each of all possible sequences of a…

A: Proteins are long chains of single amino acids. The human body uses 20 different amino acids in…

Q: Five amino acids were subjected to normal phase chromatography, and the folkowing Rf val were…

A: Chromatography is the technique of separation of components of a mixture based on their physical…

Q: Consider the following peptide sequence: His-Pro-Lys-Arg-Ala-Gln-Ser-Cys-Pro Which test will the…

A: Proteins are polymers of amino acids in which the amino acids are linked together by peptide…

Q: Differentiate the difference between saturated fat and unsaturated fat. Explain the chemical…

A: Fatty acids are important micromolecules which combine together to form lipids in plants, animals…

Q: Yeast fermentation is of a value in making baked products due to the release of: Select one: O a.…

A: Fermentation occurs in the yeast in anaerobic conditions. Alcoholic fermentation occurs in the…

Q: chemicals being applied for the leafy vegetables to produce seeds? If yes,

A: In today's world , almost all grown vegetables are being sprayed with pesticides, fungicides and…

Q: 19. For the helix in double-stranded B-form DNA, the majority of the stability of the DNA can be…

A: Hi! Thank you for the question, as per the honor code, we are allowed to answer the…

Q: Briefly describe the following and give examples. 1. Monosaccharides 2. Disaccharides 3.…

A: 1. Monosaccharides - they are simple carbohydrates that consist of a single polyhydroxy aldehyde or…

Q: In which type of segregation, genetic information is gained? Alternate Adjacent Both None

A: Principle of Segregation genes explains how pairs of gene variants are separated into reproductive…

Q: What is the composition of minimal initiation complex during transcription? TBP, TAF, TFIIA, TFIIB,…

A: In eukaryotes several transcription factors are necessary for the basal expression of an eukaryotic…

Q: Xanthoproteic Test (+) Millon's Test (-) Pauly Test (+) Biuret Test (-) Which peptide will yield the…

A: Polypeptides are amino acids linked together by peptide linkages.

Q: As the smallest unit of lipids is a glycerol, whereas, the amino acid is the smallest unit for…

A: Introduction: Amino acid is a compound that contains amino and a carboxyl group with a unique side…

Q: In the RBCs of the patient in the picture, which of the following would be expected? Explain. A.…

A: Red blood cells (RBCs) are the blood cells, which help to carry oxygen from the lungs to the tissues…

Q: Are proteins and enzyme the same in its structure and function. Why? Explain and provide an example…

A: Introduction: The human body contains a number of cells that perform various functions with the help…

Q: Since pepsin is a gastric enzyme, does it have an acidic or alkaline optimum pH? • What happens to…

A: The gastric juice comprises of water, mucus, hydrochloric acid, pepsin, and intrinsic factor and…

Q: What is the name of the predominant amadori molecule product in the binding of hemoglobin and…

A: Excess glucose can react nonenzymatically with the amino groups of intracellular and extracellular…

Q: topic: gel electrophoresis What is the purpose of the running buffer?

A: The gel electrophoresis is a biochemical technique, which helps to separate the proteins and DNA,…

Q: What are the control mechanisms of glycolysis and the Krebs cycle.

A: The question is all about the process involve in respiration like glycolysis and kreb cycle in which…

Q: Which polymerase transcribes genes with internal control regions (ICR)? O RNA Pol I RNA Pol III RNA…

A: The eukaryotic cells have three distinct RNA polymerases that transcribe different sets of genes.

Q: What is the difference between the two salt precipitation methods: salting in and salting out?…

A: The solubility of a protein in solution depends on the concentration of the salt present in…

Q: Calculate the number of phosphates, deoxyribose and ribose, and nitrogenous bases needed for a:…

A: Nucleic acid can be of 2 types: DNA (deoxyribonucleic acid) RNA (ribonucleic acid) DNA carries…

Q: How many ATP couny after complete oxidation 1 mol glucose

A: Metabolism includes biosynthesis/ reduction (an anabolic process) and oxidation (catabolic…

Q: What is the function of the sliding clamp at a replication fork?

A: Replication is a process to produce daughter DNA from parent DNA. Sliding clamp is a ring shaped…

Q: Membranes with unsaturated fatty acids in their components are more flexible and fluid because:…

A: The biological membranes are made up of fatty acids molecules which are arranged in a bilayer…

Q: 23. The following data describe the cleavage of peptide bonds in small peptides by the enzyme…

A: Introduction: Serine proteases are a large group of enzymes that cleaves the amide bond and…

Q: How are the organelles in a cell similar to the organs in a human body? Explain in 3-5 sentences.

A: Organelles are cellular components, which perform specific functions inside the cell. Different…

Q: Match the following methods of Analysis Fractional analysis, methylation, and periodate oxidation A.…

A: Methods of analysis are different techniques used to analyse a compound for determination of its…

Question

VIII - BIOMOLECULES Instructions : - Answer the question properly. - Please do not copy here in Bartleby - Explain why did you choose that answer in 3-5 sentences.

8. Which of the following takes place due to phosphorylation of isocitrate
dehydrogenase?
a) Inhibits the binding of citrate at active site
b) Degrades the enzyme
c) Enhances the substrate-binding affinity
d) No reaction

Carbon-based molecules made by living things. The four categories of biomolecules—proteins, lipids, nucleic acids, and carbohydrates—compose living things and carry out their chemical processes.

Expert Solution

This question has been solved!

Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.

SEE SOLUTION Check out a sample Q&A here

Isocitrate dehydrogenase

VIEW

Phosphorylation of isocitrate dehydrogenase

Final answer

Step 4

Step 5

Step by step

Solved in 5 steps

SEE SOLUTION Check out a sample Q&A here

Similar questions

1) How is the TCA cycle regulated? a) Draw the TCA diagram that fills in all possible regulation points.
What chemical is the structural basis of the bile salts, Vitamin D, and all of the steroid hormones to include estrogen, progesterone, and testosterone? A) Cholesterol B) Arginine C) Glucose D) Acetyl CoA E) Glucose-6-dehydrogenase
Which of the following is not associated with Perilipin? A) when phosphorylated, it re-structures fat droplets for easy degradation of triacylglycerols B) is a fat droplet-associated protein C) is phosphorylated when glucagon and epinephrine levels are high D) when phosphorylated, it helps to degrade the coactivator of ATGL Next Page Page 4 of 125
If PFK is activated in the liver, which of the following statements would be false? a) There are high levels of fructose 2,6 bisphosphate b) PFK is in the R-state c) Glycolysis would be activated d) AMP levels are low e) Gluconeogenesis is inhibited in the liver
In the liver, what is the major regulation that dictates fate of pyruvate vs lactate? (This can tie into reading assignment!) a) Activation of MCT1 to transport lactate out of cell b) Activation of pyruvate carboxylase and conc dictating use of lactate dehydrogenase, inhibition of PDHC c) Activation of lactate dehydrogen, inactivation of pyruvate carboxylasease and PDHC d) Activation of lactate dehydrogenase and MCT1 (transporter)
8. Ketone bodies were found in the urine of the patient with diabetes mellitus. Explain the sequence of metabolic changes resulting in ketonuria. For that answer the question and do the following tasks: a) what are the ranges of ketone bodics in blood of the healthy pcople and the patients with diabetes mellitus? b) explain the main changes in hormonal regulation of patient with diabetes mellitus; c) explain why the level of free fatty acids in the blood is clevated; d) name the pathways of lipid metabolism which becomes more active in patients with diabetes mellitus; e) draw the scheme of ketone body synthesis and oxidation.
1. With the prevalence in food of peeled cereals or bread made from high-grade flour, hypovitaminosis B1 may occur. Explain the role that vitamin B, plays in the body. For this: a) name the coenzyme which contains vitamin B, and enzymes, which require this cocnzyme to function; b) write the process in which these enzymes are involved and explain how the process speed will change with a lack of B,; d) what discase develops in the absence of vitamin B,.
37) The autocatalytic activity of trypsin describes the action of a. trypsin on procarboxypeptidase b. trypsin on chymotrypsin c. both a) and b) d. trypsin on pepsinogen e. trypsin on trypsinogen
A 9 year old mentally retarded girl with a protuberant abdomen, short stature, coarse facial features and cloudy corneas. skeletal malformations include dysostosis Multiplex and Bullet shaped middle phalanx .what is the enzyme deficient in this patient? A)Iduronate sulfatase B) beta - Galactosidase C)alpha - L- Iduronidase D) beta - Glucuronidase
30. Which type of diabetes is typically not treated with insulin? A) Type I diabetes B) Type II diabetes C) Gestational diabetes D) Idiopathic diabetes (such a cystic-fibrosis diabetes) Type Ib
Serum concentrations of acetoacetate and ß-hydroxybutyrate increase dramatically after a 3-day fast primarily because of the increased rate of which of the following?A) Fatty acid oxidation in liverB) Fatty acid synthesis in liverC) Glycogenolysis in liverD) Glycolysis in skeletal muscleE) Protein degradation in skeletal muscle
8. In patients after prolonged hepatitis, the ALT and AST activities were measured in the blood serum. What transaminase activity is inereased to a greater extent, and why? For the answer: a) explain the meaning of the enzyme diagnostics; b) draw the scheme of reactions catalyzed by ALT and AST; c) point out coenzyme of these reactions; describe vitamin from which this cocnzyme is derived; d) describe the biological importance of this type of reactions in amino acid metabolism; e) specify the demands which are claimed to enzymes been used in enzyme diagnostics.