7. To improve the digestion of food proteins in chronic inflammatory-dystrophic disorders of the pancreatic gland, stomach or intestine patients are prescribed mezym forte (pancreatin) containing pancreatic enzymes. What is the remedial mcchanism of this drug? For the answer: a) enumerate enzymes digesting proteins in the gastrointestinal tract; b) specify the mechanism of proteolytic enzyme activation; c) draw the schemes of these enzymes activation, point out the activators; d) explain the specificity of proteases; e) describe the consequences of these enzymes activation in the tissue of pancreas.
Q: The reaction ATP to ADP + Pi is typically part of a(n) ________ reaction. a) free radical b) oxida...
A: Enzymes mediate six primary kinds of biochemical processes in living systems. These include group tr...
Q: TRUE OR FALSE Palmitic oil is (soluble) to hot ethanol and chloroform.
A: Hi. Thank you for the question. The second question looks incomplete. Please provide the details abo...
Q: 3. The Lysine-rich (KKRPKPGG) octapeptide sequence has been shown to bind selectively to a class of ...
A: Proteins are polymers of amino acids linked by peptide/amide bonds with release of the water molecul...
Q: Analyzing: Analyze the following pair of monosaccharides and determine which of the following is an ...
A: Since there are multiple questions and they are not interlinked, as per our company guidelines only ...
Q: 8. What should be approximate wavelength of the depletion laser in a STED microscope for imaging of ...
A: Stimulated emission depletion (STED) microscopy is a super resolution microscopy, which is based on ...
Q: When the enzyme is incubated with oxaloacetate, will oxaloacetate be observed?
A: Many amino acid biosynthetic pathways involve transamination reactions. The α-amino group from one ...
Q: How did your soap compare to the commercially prepared soap?
A: If we wash oily/ greasy hands with soap then only oil/grease gets removed. In the sam...
Q: Discuss how carbohydrates can be stored as fat. Please answer precisely, clearly, and directly.
A: Carbohydrates are the primary source of energy for the body, and glucose is the simplest form of car...
Q: Define about primary miRNAs (pri-miRNAs) ?
A: MicroRNAs (miRNAs) are small regulatory RNAs derived from stem-loop sections of original transcripts...
Q: Predict the results you would get if your Cytosine DNA sample was inadvertently contaminated with th...
A: DNA is a nucleic acids and polymer of nucleotides linked by phosphodiester bonds. It is composed of ...
Q: REAC 447: Qualitative Testing for Lipids 6. Describe a method or test you could use to distin- guish...
A: Biological lipids are a chemically diverse group of organic compounds which are insoluble or poorl...
Q: 8. "Salting-out" is a process A. to represent the certain molecules are ionized in a solution B. whe...
A: Salt is a molecule composed of positive and negative ions when dissolved in water. Salt molecules ar...
Q: INTRUCTIONS: - Do not copy here in BARTLEBY or GOOGLE - PLEASE ANSWER PROPERLY Failed to follow inst...
A: The most prevalent lipids in nature are fats and oils. They give life energy, protect bodily organs,...
Q: H* ions generated by reactions in the electron transport chain, as well as H* ions present in the ma...
A: The ETC is an ordered arrangement of electron carriers in the inner mitochondrial membrane. They are...
Q: Chicken egg contains a lot of proteins which supports the growth and development of the chicken embr...
A: Proteins are composed of twenty standard amino acids attached together via peptide bonds. The linear...
Q: . The allele B gives mice a black coat, and b gives a brownone. The genotype e/e of another, indepen...
A: When genes are on different chromosomes or are separated by a large distance on the same chromosome,...
Q: ive examples of drugs that are monoamine oxidase inhibitors.
A: Enzymes are highly specific. All cellular reactions or processes are mediated by en...
Q: The discussion this week explores the reasons why carbon dioxide changes the affinity of oxygen to h...
A: Hemoglobin is a respiratory pigment present in red blood cells. It is a conjugated protein and gives...
Q: You
A: The synthesis of enzymes is carried out in a submerged liquid state.The reaction of enzymes increase...
Q: What are the advantages of gel filtration as a technique for protein purification? Identify two type...
A: Gel filtration is used to seperate a mixture of proteins only on the basis of molecular weight. The ...
Q: Unique features and function of all 20 major amino acids
A: Amino acids form a larger component of the body in the form of proteins. They are generally divided ...
Q: Applying: Prokaryotic and eukaryotic cells have many differences, but they also share some common fe...
A: Prokaryotes are microscopic single-celled organelles that lack nuclear envelopes. Their cell wall is...
Q: Substrates and reactive groups in an enzyme’s active site must be precisely aligned in order for a p...
A: Enzymes catalyse (speed up) chemical reactions; in certain situations, enzymes may make a chemical r...
Q: why chromotography isn't a good fit to detemine mitochondrial RNA polymerase
A: Mitochondrial RNA polymerase (mtRNAP) is vital for biogenesis of mitochondria as well as mitochondri...
Q: Which of the following structural features are involved in the formation of a peptide bond? amino gr...
A: A polypeptide chain is a polymer of naturally occurring amino acids that are linked together by a pe...
Q: Give an alternative form of CpG methylation, given clear handwritten explaination!
A: DNA methylation is known to be one of the major epigenetic marks. The cytosines that are methylated ...
Q: What structure is common to virus, prokaryotes and eukaryote? What are their major structural differ...
A: Viruses are the entities that are made up of Proteins encapsulating nucleic acid either DNA or RNA. ...
Q: What is Intron retention type of alternativesplicing ?
A: A portion in mRNA that codes for protein is termed as exon. The non-coding region is termed as intro...
Q: 1.Fructose and galactose can be distinguished by which of the following reagents? * a.Fehling’s reag...
A: Both glucose and fructose are monosaccharides. Glucose is aldohexose and fructose is a keto hexose. ...
Q: 6. Amino acid alanine containing NE isotope in a-amino group was administrated to mouse with food. I...
A: The use of radioactive labelling of particular atoms have often been used to determine metabolic pat...
Q: 4: CASE ANALYSIS Over the course of many months, a previously healthy 58-year-old lady develops inc...
A: The condition from which she is suffering is:
Q: Discuss the factors that affect the 260/280 ratio
A: The 260/280 ratio is the ratio of absorbance of a sample at 260 nm to its absorbance at 280 nm.. Thi...
Q: What is the correct name of this linear glucose molecule, and how many chiral carbons does it have?
A: Carbohydrates are the basic energy source of organisms. They include glucose, fructose, lactose, and...
Q: Give four enzymes that are being used in medical therapy. Report two industrial uses of enzymes and ...
A: Enzymes - Used for catalyzing various reactions for therapeutic , industrial uses
Q: What determine the RNA Spliceforms of a Gene Are Translated ?
A: The initial RNA that is transcribed from a gene's DNA template must be processed before it becomes a...
Q: What is population? Describe its different characteristics with suitable examples
A: Population is a term used for addressing individuals of a species that coexist in a particular habi...
Q: 2. A biochemical analysis of an RNA sample showed 40 % ofnitrogenous bases were cytosine (C). What p...
A: Nucleic acids are macromolecules. These are of two types - Deoxyribonucleic acid (DNA) and Ribonucle...
Q: The comparative form of far is more far
A: This statement given is not correct grammatically. There are three forms of comparison that we use i...
Q: What is the effect of gastric juice on the digestion of proteins in the stomach? Precise and direct ...
A: Gastric juice is also called as Gastric acid and have pH around 2-3. It is released by stomach linin...
Q: 1. What trend did you observe for the rate of peroxidase compared to the variable tested?
A: The enzyme peroxidase is responsible for catalyzing the reaction which converts H2O2 to H2O. Here th...
Q: Define about cis-regulatory sequences on the mRNA ?
A: mRNA - It has the tripartite structure with a 5' untranslated region( UTR), and coding region follow...
Q: An enzyme is present at 100 nM (nanomolar) and has a Vmax value of 25 uM/s (micromolar/second). The ...
A: Enzyme concentration= 100 nM Vmax value= 25 uM/s Km for substrate = 5.2 uM
Q: What is the difference between lysine and arginine? which sidecchain is easier to move across the me...
A: Lysine and arginine are amino acids which forms proteins. Amino acids are organic compounds which co...
Q: describe and explain the physiological and biochemical perturbations in plants caused by flactuation...
A: Stress is any adverse environmental condition also called as abiotic factors collectively hampers g...
Q: rollowing -passed; 1.e., odui ucing nto the electron transport chain without using this complex are ...
A: ETC or electron transport chain is the process which leads to ATP synthesis. The ETC occurs in the i...
Q: Glucose 6 phosphatase O allows muscle to release free glucose into the bloodstream O is expressed in...
A: Glucose 6-phosphatase is an enzyme that makes hydrolyze glucose 6-phosphate, which leads to the form...
Q: A Meselson-Stahl-experiment was performed to study the DNA replication of a newly discovered bacteri...
A: The DNA is a double helical structure composed of 2 strands of DNA intertwined with each other in th...
Q: 7. RNA molecule cannot have secondary structure. DNA double-stranded form is maintained by hydrogen ...
A: The DNA and RNA molecular structures have particular conformation and bonding. Both the structures a...
Q: Discuss and differentiate the purpose and examples of macro and micronutrients?
A: Nutrients are chemical substances which are required by body for various processes. These are requir...
Q: Describe the skeletal system and the role it plays during cell division.
A: The cellular cytoskeleton is constituted of microtubules, microfilaments and intermediate filaments....
Step by step
Solved in 2 steps with 1 images
- 5.Aspirin isthedrug,used for the decreasing ofinflammatory reaction and temperature. 1)Describe the mechanism of aspirin action. 2) What types of reversible inhibition do you know.3)Give the examples of drugs acting as such inhibitors.6. Serum blood of a patient with dislipoproteinemia type I has milky appearance even in fasting. If serum stays at low temperature (4) for several hours, the fatty layer appears on its surface. What are the possible causes of these symptoms? Answer the questions and do the following tasks: a) what compounds of serum blood must be tested in the patient in a biochemical lab? b) what is the possible diagnosis of the discase? c) draw the reaction which does not occur properly in the patient's blood; d) explain how the products of the previous reaction are used in adiposc tissue and heart in a healthy person I hour after meal.During HAART therapy for Human Immunodeficiency Virus (HIV), what are the rationale and mechanisms of action for NRTIs, NNRTIs, and protease inhibitors?
- A 9 year old mentally retarded girl with a protuberant abdomen, short stature, coarse facial features and cloudy corneas. skeletal malformations include dysostosis Multiplex and Bullet shaped middle phalanx .what is the enzyme deficient in this patient? A)Iduronate sulfatase B) beta - Galactosidase C)alpha - L- Iduronidase D) beta - GlucuronidaseMrs. Anderson, a 45-year-old woman with a history of chronic back pain, has been taking X as prescribed by her rheumatologist for the past eight months. During a routine check-up, her liver function tests revealed significantly elevated liver enzymes. She has not experienced any noticeable symptoms but is now being closely monitored for potential liver-related issues. 2. Propose a pharmacoepidemiological study design to confirm or refute the signal of hepatotoxicity associated with X. Consider factors such as study population, exposure definition, and outcome measures. Discuss the strengths and limitations of your chosen study design? Outline the methods and data sources that could be used to collect information on hepatotoxicity in patients using X.? Discuss how the findings of the study could have regulatory implications. If a significant association is identified, explore how regulatory agencies might implement other measures to ensure patient safety.? Develop communication…6. More enzyme activity.... A) Discuss how proteolytic cleavage is used to achieve tight control of the activity of digestive enzymes. B) If proteolytic cleavage leads to irreversible activation of digestive enzymes, how is the activity of digestive enzymes reduced when no longer needed? There were two ways presented this semester. C) We looked at three serine protease enzymes: elastase, chymotrypsin, and trypsin. All three enzymes cut peptide bonds using a similar catalytic mechanism. Explain why these are called serine proteases. D) What are the different substrate specificities of elastase, trypsin, and chymotrypsin? And, why, from a structural standpoint, do elastase, trypsin, and chymotrypsin have different substrate specificities?
- Some are unable to taste thiourea and PTC. DNA sequence results for these individuals show a normal predicted amino acid sequence for the TAS2R38 gene. Provide an explanation that can account for insensitivity to thiourea. (a) First assuming a mutation involving the TAS2R38 gene (b) Then assuming a mutation in a gene other than TAS2R38Describe the enzymatic reaction of the protein epidermal growth factor. Include the specific reaction catalyzed by the protein. Enzymatic reaction is a physiologically relevant biochemical stimulus for the temporal and spatial control of drug release because: (1) the overexpression of specific enzymes is localized at diseased tissues.8. In patients after prolonged hepatitis, the ALT and AST activities were measured in the blood serum. What transaminase activity is inereased to a greater extent, and why? For the answer: a) explain the meaning of the enzyme diagnostics; b) draw the scheme of reactions catalyzed by ALT and AST; c) point out coenzyme of these reactions; describe vitamin from which this cocnzyme is derived; d) describe the biological importance of this type of reactions in amino acid metabolism; e) specify the demands which are claimed to enzymes been used in enzyme diagnostics.
- A. Elastase is activated by trypsinB. Trypsinisactivatedbyelastase Which statement is correct? Proteolytic activation of chymotrypsin from chymotrypsinogen requires cleavage of four peptide bonds. Assume that any proteases can convert 100 substrates to 100 products. Activation of one enteropeptidase can eventually lead to formation of how many chymotrypsin proteins?How are proteolytic enzymes activated in the stomach and in the small intestine? Explain why this is necessary.Enzymes MATCHING TYPE a.Erepsin b.Sutilains c.Chymotrypsin d.Urokinase e.Fibrinolysin f.Rennin g.Papain h.Alcalain i.Bromelains j. Pepsin 1.Additive to remove protein stains 2. Relieve symptoms of episiotomy 3. Isolated from human urine or obtained from human kidney cells by tissue culture techniques. 4. Treatment of blood clots within the cardiovascular system, exclusive of thrombi of the coronary and cerebral ateries. 5. Obtained from the stomach of Sus scrofa, Fam. Suidae and has a proenzyme: pepsinogen which is activated by HCl. 6. From Bacillus subtilis, used as wound debridement. 7. Coagulating enzyme that is present in the mucous membrane of the stomach of animals. Important in cheese making. 8. Crystallized from an extract of the pancreatic gland of Ox Bos Taurus used as an ophthalmic solution. 9. Mixture of protein-digesting & milk clotting enzymes from the juice of Ananas comosus used as meat tenderizer. 10. Found in the intestinal juice, Converts proteoses and…