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Description: 2. Draw a pedigree consisting of 3 generations that is consistent with X-linked recessive inheritance but not with x-linkedautosomal inheritance. (You can use pencil.)

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Biology

2. Draw a pedigree consisting of 3 generations that is consistent with X-linked recessive inheritance but not with x-linked autosomal inheritance. (You can use pencil.)

Biology: The Dynamic Science (MindTap Course List)

4th Edition

ISBN:9781305389892

Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan

Publisher:Peter J. Russell, Paul E. Hertz, Beverly McMillan

Chapter13: Genes, Chromosomes, And Human Genetics

Section: Chapter Questions

Problem 2TYK: The following pedigree shows the pattern of inheritance of red green color blindness in a family....

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2. The following is a pedigree of a family in which a rare form of X-linked colorblindness is found (filled-in symbols). II 2 II 3 4 a. Label the genotypes of as many family members as the available information permits. Remember that this gene is located on the X-chromosome when writing out genotypes. b. Is the colorblindness trait recessive or dominant? Explain how you know.
6. The pedigree below traces the inheritance of a particular disorder. Circles are females, squares are males. Shaded symbols are affected with the disorder (NOTE: "half-shaded" symbols are NOT used here, for heterozygous individuals). What is the mode of inheritance of this disorder: is it dominant or recessive? Autosomal or X-linked? What is the genotype of the three numbered individuals? 1 2. 3.
8. This family pedigree follows a family afflicted by a trait determined by the R gene IdA 2 9 10 11 12 13 14 15 16 17 18 19 e. What is the genotype of individual 1: f. What is the genotype of individual 6: g. What is the genotype of individual 2: h. What is the genotype of individual 13: i. Is this trait autosomal dominant, recessive, or X-linked recessive? Why? |
6. Identify the mode of inheritance for the following pedigree. Provide the genotypes of indicated individuals. ? Genotypes: Il-1 IV-1 V-6 Il-2 IV-2 V-12 Il-3 IV-3 V- 14 III-1 IV-4 V-16 III-13 V- 1 V-19
9. Make a pedigree for each of the following situations. For each individual, write the individual's genotype (when possible) next to the individual's symbol (e.g. O xty, I Gg): a. Two parents do not have cystic fibrosis and they have a daughter with cystic fibrosis and a son who does not have cystic fibrosis. The daughter grows up and she mates with a male who does not have cystic fibrosis. Their only child is a boy and he has cystic fibrosis. b. A man with hemophilia mates with a female without hemophilia. They have one son and one daughter. The daughter has hemophilia and the son does not have hemophilia. The son grows up, and he marries and mates with a female. Their only child is a boy, and he has hemophilia.
4. The couple shown by the pedigree shown below, have 2 children, 1 girl with the disease and 1 boy without the disease as shown. What is the mode of inheritance? (is the disease autosomal recessive, autosomal dominant, or X-linked recessive?) Explain why you think this. Fill in the genotypes to help you answer this.
II. Given the following pedigree below, use Punnett squares for each of the following possibilities: a) X- linked dominant and b) X-linked recessive in order to determine what is the mode of transmission of this trait. Disease allele = XA or Xª, depending on mode of transmission of the disease respectively. *Unaffected/No carrier-Normal Unaffected X chromosome = X I || III 1 1 2 a) X-linked recessive 9 III 6 genotype (circle one): XX * 1 2 3 11x12 4 ΧΑΧΑ 2 5 xaxa *4 6 7 8 b) X-linked dominant 11 x 12 오 XAX хах
9. Explain, giving reasons, whether the following pedigrees are compatible with autosomal dominant, autosomal recessive or X-linked dominant and X-linked recessive inheritance. (Note that a pedigree may be compatible with more than one type of inheritance.) 1:1 12 1:1 12 1:1 1:2 I12 I:4 IIS II:1 I12 II:1 I1:2 Il:3 I1:4 II2 II:1 III3 II:1 II:2 III:3 III:4 a. b. c.
9. Red-green color blindness is inherited as an X-linked recessive (Xc). If a color-blind man marries a woman who is heterozygous for normal vision, what would be the expected phenotypes of their children with reference to this character? In your answer, specify in your phenotype descriptions the gender of the children. (For example, don’t just say 75% of the children would be colorblind – you would instead say 100 % of the daughters would be colorblind and 50% of the sons would be colorblind. Note that this is not a correct answer; it is just to give you an idea of how to explain the correct phenotypes of the cross.)___
6. For the pedigree below, does it show an Autosomal Dominant, Autosomal Recessive or X-linked trait? Choose one and show the probable genotypes for every person. 어머머
5 The pedigree shown below is from a family with albinism. Albinism is a genetic condition that occurs when the body is unable to make or distribute melanin, a pigment that gives color to skin, hair, and the iris of the eye. The pedigree shown below is from a family with albinism. Analyze the pedigree to determine whether albinism is inherited in a dominant or recessive fashion, and then apply the correct genotypes to individuals 1-1, 1-2, II-2, and II-5. = 11 ||| 1 aa 1 2 3 Aa 1 3 2 4 6 A_ 7 5 8 6 9 AA 10 по по Aa male female affected individual
6. A person is simultaneously heterozygous for two autosomal genetic traits. One is a recessive condition foralbinism (alleles A and a); this albinism gene is foundnear the centromere on the long arm of an acrocentricautosome. The other trait is the dominantly inheritedHuntington disease (alleles HD and HD+). TheHuntington gene is located near the telomere of oneof the arms of a metacentric autosome. Draw all copies of the two relevant chromosomes in this person asthey would appear during metaphase of (a) mitosis,(b) meiosis I, and (c) meiosis II. In each figure, labelthe location on every chromatid of the alleles forthese two genes, assuming that no recombinationtakes place.