Which of the following statements is correct about the development of T cells?O After many cell generations, some of the CD8+ T cells differentiate into at least six functionalphenotypes.- T cells differentiate into progenitor cells destined to become (1) natural T regulatory (Treg) cells, (2)natural killer T (NKT) cells, (3) gamma/delta T cells, and (4) alpha/beta T cells.Activation by its specific antigen causes a T helper cell (TH) cell to mature into a cytotoxic Tlymphocyte (CTL) that functions to destroy host cells that have been infected by intracellularpathogens, such as a virus, or have altered MHC surface proteins.T cells originate from CD34+ stem cells in the bone marrow, where they also mature.

T cells, including CD4+ T cells (T helper cells) and CD8+ T cells (cytotoxic T lymphocytes), develop…

Answered: Which of the following statements is…

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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Similar questions

Match the term with its correct description. Transcription factor required for T-cell development Composed of superdimer, CD3 and zeta chain Facilitates the expression of tissue-specific genes in thymic epithelium Selection for thymocytes which recognize self MHC molecules Elimination of thymocytes which recognize self Negative selection Notch 1 Pre-T-cell receptor Positive selection ✓AIRE Choose... Choose... Choose... Choose... $ ✪
Some immune system cells like B lymphocytes and T lymphocytes must first be "trained" in either the bone marrow or thymus because they can do their jobs. Which of the following best describes the purpose of this "training" during their maturation? to selectively remove any lymphocytes that show immunity against our own cells and our own antigens in our body to expose these cells to all of the potential pathogens and their antigens they may encounter in the future to activate them so that they differentiate into plasma and memory cells and begin producing antibodies to make sure that each lymphocyte is capable of recognizing a large number of different pathogen antigens to initiate a secondary and stronger immune response after encountering an invading pathogen
What problems would arise if a person had a hereditary deficiency that resulted in an inability to present antigens to T cytotoxic cells? What would the problem be if the person had a deficiency in presenting antigen to generate Th 1 (T helper 1) cells or (T helper 2) cells? Could a person having any one of these deficiencies survive in a normal environment
Which of the following is NOT true about T cells?(a) T cells develop from lymphoid stem cells in the bonemarrow and mature in the thymus.(b) Cell-mediated immunity is primarily carried out by Tcells.(c) Subsequent differentiation of T cells produces cytotoxic(killer) T cells, delayed-hypersensitivity T cells, helper Tcells, and regulatory T cells.(d) Natural killer cells (NK) are exclusively differentiated Tcells.(e) T cells act in situations where antigens are embeddedin cell membranes or are inside host cells and thus areinaccessible to antibodies.
During the early developmental stages of α:β T cells in the thymus, there are two key checkpoints that must be satisfied to permit the progression of T-cell development. Explain what occurs at each checkpoint.
Compare and contrast the morphology of the adult and infant thymus. (i) Describe 1 way that they are similar in structure and 1 way that they are different in structure? (ii) What do these differences signify about the role of the thymus in T cell development in infants versus adults?
Put the following steps in order for cell-mediated immunereactions:(a) Differentiated T cells include T helper, delayed hyper-sensitivity, cytotoxic, and memory T cells that all havedifferent immunological functions depending on the an-tigen presented.(b) Antigen-presenting cells (macrophages and dendriticcells) phagocytize pathogens, ingesting and degradingthem into pieces which are transported to the surface ofthe cell.(c) T cells bearing the corresponding receptor for the pre-sented antigen bind to it and become activated only ifthe appropriate MHC is also present.(d) Some pieces of the pathogen’s antigens are processedby inserting them into the antigen-presenting cell’smembrane and are held in place by class II majorhistocompatibility complex (MHCII) proteins.(e) Activated T cells are stimulated to divide and differen-tiate into different types of T cells, including memorycells
that causes the rapid reproduction of a specific ( Select] [ Select ] Antigenic cell B cell I cell Macrophage Eosinophil Vaccines work by stimulating a(n) [Select ] that produces an antibody that is specific for the antigen in the vaccine. This creates a pool of memory cells that will be available if the person is ever infect nicrobe.
Briefly describe the effector functions and mediators of the following CD4 T lymphocyte subsets. List the cytokines and principal transcription factors that induce differentiation of CD4 T cells into these subtypes. (i) Th1 cell (ii) Th2 cel
Clonal Selection Hypothesis is the most accepted theory for how immune cells respond to specific antigens. Explain the clonal selection hypothesis. Use the autoimmune response, and immunological memory to suggest why the hypothesis may be correct….or not?(150 words) must include underlined dark words
A mouse is infected with staphylococcal bacteria through a laceration in the skin of its paw. Dendritic cells are isolated from the tissue at the site of infection, and are incubated together with naïve staphylococcal-specific CD4 T cells. Seventy-two hours later, the proliferation of the CD4 T cells is measured as a readout for T cell activation. Surprisingly, the T cell response is quite poor compared to the response observed when the same T cells are mixed with a comparable number of dendritic cells isolated from the draining lymph node of the infected mouse. A comparison of the dendritic cells isolated from the two different sites would reveal: Much higher levels of MHC and B7 molecules on the lymph node dendritic cells than those from the infected tissue Much higher expression of all TLRs in the lymph node dendritic cells than those from the infected tissue An increased number of MHC class II molecules bearing bacterial peptides on the surface of dendritic cells from the infected…
Naive T cells in CD69-knockout mice might: Group of answer choices Have a defect in recognizing antigen on activated dendritic cells Not be detained in the lymph node to get activated Have a defect in lymph node entry and accumulate in the blood Have a defect in responding to inflammatory cytokines in the lymph node Remain trapped in lymph nodes and fail to recirculate asap please.

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