I need help calculating observed allelic frequencies. I'm in a biology lab and we did a classroom experiment where we were each given genotypes and simulated multiple generations by coinflip. This is the end data after multiple generations and we need to extrapolate p & q: AA individuals - 2 Aa individuals - 13 aa individuals - 5 My understanding is that the genotypic frequencies would simply be their %. So AA would be 0.1, Aa would be 0.65, and aa would be 0.25. This should mean that AA = 0.1 = p^2 and aa = 0.25 = q^2. Which should also mean that taking the square root of these numbers would give me p and q.... but they don't add up to 1. Squaring them gives me a p value of ~0.32 and a q value of 0.5. How is this possible? Shouldn't this method work to give me p and q since I know the exact genotypic frequencies? If anyone can clear up why this doesn't work, I would be extremely appreciative. Thank you!

I need help calculating observed allelic frequencies. I'm in a biology lab and we did a classroom experiment where we were each given genotypes and simulated multiple generations by coinflip. This is the end data after multiple generations and we need to extrapolate p & q: AA individuals - 2 Aa individuals - 13 aa individuals - 5 My understanding is that the genotypic frequencies would simply be their %. So AA would be 0.1, Aa would be 0.65, and aa would be 0.25. This should mean that AA = 0.1 = p^2 and aa = 0.25 = q^2. Which should also mean that taking the square root of these numbers would give me p and q.... but they don't add up to 1. Squaring them gives me a p value of ~0.32 and a q value of 0.5. How is this possible? Shouldn't this method work to give me p and q since I know the exact genotypic frequencies? If anyone can clear up why this doesn't work, I would be extremely appreciative. Thank you!

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter19: Population Genetics And Human Evolution

Section: Chapter Questions

Problem 9QP: Using the HardyWeinberg Law in Human Genetics Suppose you are monitoring the allelic and genotypic...

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