Campbell Biology
12th Edition
ISBN: 9780135188743
Author: Urry
Publisher: PEARSON
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Textbook Question
Chapter 11.4, Problem 1CC
How can a targct cell's response to a single hormone molecule result in a response that affects a million other molecules?
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How could you determine whether a hormone-mediated response hasresulted from the intracellular mediator mechanism or the nuclearreceptor mechanism?
Which of the following observations can be explained by the properties of hormone receptors?
a) A certain tissue can react to more than one hormone
b) A certain hormone affects only a specific tissue, not all tissues
c) Some tissues react very quickly to a certain hormone, other tissues take many hours to react to the same hormone
Which type of hormone receptor—plasma membrane bound or intracellular—would be expected to provide the most long-lived response to hormone binding and why?
Chapter 11 Solutions
Campbell Biology
Ch. 11.1 - Explain how signaling is involved in ensuring that...Ch. 11.1 - In liver cells, glycogen Phosphorylase acts in...Ch. 11.1 - Prob. 3CCCh. 11.2 - Prob. 1CCCh. 11.2 - WHAT IF? What would the effect be if a cell made...Ch. 11.2 - MAKE CONNECTIONS How is ligand binding similar to...Ch. 11.3 - What is a protein kinase, and what is its role in...Ch. 11.3 - When a signal transduction pathway involves a...Ch. 11.3 - What is the actual signal that is being transduced...Ch. 11.3 - WHAT IF? If you exposed a cell to a ligand that...
Ch. 11.4 - How can a targct cell's response to a single...Ch. 11.4 - WHAT IF? If two cells have different scaffolding...Ch. 11.4 - Prob. 3CCCh. 11.4 - Prob. 4CCCh. 11.5 - Give an example of apoptosis during embryonic...Ch. 11.5 - WH AT IF? If apoptosis occurred when it should...Ch. 11 - What determines whether a cell responds to a...Ch. 11 - How are the structures of a GPCR and an RTK...Ch. 11 - What is the difference between a protein kinase...Ch. 11 - What mechanisms in the cell terminale its response...Ch. 11 - What is an explanation for the similarities...Ch. 11 - Binding of a signaling molecule to which type of...Ch. 11 - The activation of receptor tyrosinc kinases is...Ch. 11 - Lipid-soluble signaling molecules, such as...Ch. 11 - Consider this pathway: epinephrine G...Ch. 11 - Apoptosis involves all but which of the following?...Ch. 11 - Which Observation suggestcd to Sutherland the...Ch. 11 - Prob. 7TYUCh. 11 - DRAW IT Draw the following apoptotic pathway,...Ch. 11 - EVOLUTION CONNECTION Identify the evolutlonary...Ch. 11 - Prob. 10TYUCh. 11 - SCIENCE, TECHNOLOGY, AND SOCIETY The aging process...Ch. 11 - WRITE ABOUT A THEME: ORGANIZATION The properties...Ch. 11 - SYNTHESIZE YOUR KNOWLEDGE There are five basic...
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- Suppose that the circulating concentration of hor-mone is 10–10 M and the Kd for binding to its receptor is 10–8M. What fraction of the receptors will have hormone bound?If a meaningful physiological response occurs when 50% ofthe receptors have bound a hormone molecule, how muchwill the concentration of hormone have to rise to elicit aresponse? The fraction of receptors (R) bound to hormone(H) to form a receptor–hormone complex (R–H) is [R–H]/([R] + [R–H]) = [R–H]/[R]TOT = [H]/([H] + Kd).arrow_forwardWhy is knowing the KD of a hormone / receptor complex important?arrow_forwardHow is it that the reaction of a single target cell to a single hormone molecule may have an effect on a million other molecules?arrow_forward
- How can a target cell’s response to a single hormonemolecule result in a response that affects a million othermolecules?arrow_forwardIn the endocrine system, it asks, "describe the two major mechanisms by which hormones bring about their effect on their target tissues?"I was thinking it was polar and non polar soluble because that's the major component when it comes to how cells react to their hormones, it determines how fast the reaction time.arrow_forwardHormone receptor molecules are the key to understanding specific-ity of hormone action on target cells. Describe and distinguish be-tween receptors located on the cell surface and those located in the nucleus of target cells. Name two hormones whose action is medi-ated through each type of receptor.arrow_forward
- How could the origin of endocrine control systems lie in ordinary cellular events? How might the earliest multicellular organisms have evolved some sort of endocrine coordination?arrow_forwardWhat would happen if there is no receptor for the hormone on the cell?arrow_forwardA new hormone is discovered. Analysis suggests that it is synthesized on demand and has a long half-life in the wwww www. bloodstream. It seems to activate gene transcription in its target cells, though no cell surface receptors can be identified. Which type of hormone is this most likely to be? A) Steroid hormone B) Catecholamine C) Thyroid hormone D) Peptide hormonearrow_forward
- Some cancer cells release their own grown hormone rather than relying on growth hor- mones from elsewhere in the host organism. Which of the following describes the type of cell communication used by these cancer cells to promote their continued division? A juxtacrine signaling B с D endocrine signaling paracrine signaling autocrine signalingarrow_forwardDoes the following table properly summarize negative feedback loop of each tropic hormone? If not, place the correct answer beside each box.arrow_forwardWhich of the statements is/are incorrect for hormones? 1) Hormones are non-nutrient chemicals serving as intercellular messengers. 2) Hormones are molecules of low molecular weight and are produced in traces. 3) Hormones give energy and also effect metabolism and growth activities of target cells. 4) Many hormones are produced in inactive form.arrow_forward
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