Your 67 YO 195lb, 5ft 10in male patient diagnosed with testicular cancer has been prescribed ifosfamide 1200mg/M2/day IV for 5 days. You calculate the BSA using the mosteller method as being 2.09m2. Ifosfamide is available in 60mL vials contianing 3g of drug. a) How many mL will you administer each day?
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Your 67 YO 195lb, 5ft 10in male patient diagnosed with testicular cancer has been prescribed ifosfamide 1200mg/M2/day IV for 5 days. You calculate the BSA using the mosteller method as being 2.09m2. Ifosfamide is available in 60mL vials contianing 3g of drug.
a) How many mL will you administer each day?
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- Your 64YO 152lb, 5ft 8in female patient daignosed with advanced bladder cancerhas been prescribed ifosamide 1500mg/m2/day IV for 5 days. You calculate the BSA using the Mosteller method as being 1.82m2. Ifosfamide is available in 60mL vials containing 3g of drugs. How many mL will you administer each day?rug-B has an elimination half-life of 9 hours, an absorption half-life of 20 minutes and linear harmacokinetics. In a patient, the plasma concentration five hours from the administration of two 60 mg cablets of the drug is 8 ug/mL. What would you expect to be the plasma concentration five hours from the administration of one 60 mg tablets? 1 ug/mL Answer 1-1The drug dosage for the patient is calculated using a BSA of 1.9m2. If the order is 15mg per m2, how many milligrams is the desired dose?
- Consider the following from the Ampicillin for Injection, USP package insert: For Intramuscular Use: Label Claim 250mg 500mg 1g 2g Amount of Diluent (mL) Approx. Volume (ml) 0.9 1.7 3.4 6.8 1 2 4 8 a) What is the amount of diluent needed to reconstitute a 1 g vial? b) What is the powder volume for a 1 g vial of ampicillin? Approx. Concentration (mg/mL) 250 250 250 250 Later in the package insert you see: For Direct Intravenous Use: Add 5 mL Sterile Water for Injection or Bacteriostatic Water for Injection to the 250 and 500 mg vials and administer slowly over a 3 to 5-minute period. Ampicillin for Injection, 1 g or 2 g, may also be given by direct intravenous administration. Dissolve in 7.4 or 14.8 mL Sterile Water for Injection or Bacteriostatic Water for Injection, respectively, and administer slowly over at least 10 to 15 minutes. c) What is the amount of diluent needed to reconstitute a 1 g vial of ampicillin for direct IV injection d) What is the total amount of volume that will…A 145lb patient is to receive a single IV dose of ondansetron 0.15mg/kg, in addition to other drugs, for prevention of chemotherapy-induced nausea and vomiting. Ondansetron is available in a 20mL MDV of 2 mg/mL. How many mL will you administer?You are requested to recommend a dosage regimen for a patient (5S years old, 80 kg) to achieve plasma levels of 25 mg/L of an antiepileptic agent with an elimination half-life of 11 hrs and an apparent Vd of 0.02 L/kg. The tablets are 75% bioavailable and are available as 10 mg and 40 mg tablets. The ideal dosage regimen for this patient is: 10 mg twice daily 10 mg four times a day 40 mg daily 40 mg twice daily
- Erythromycin lactobionate 500 mg Dexamethasone Na phosphate 100 mg Glycerin 2.5 mL Sterile water for injection ad 100 mL M. ft. opthalmic solution a. what is the percentage strength of erythromycin lactobionate in the prescription? b. If glycerin has a specific gravity of 1.25, what is its concentration (in w/v) in the prescription?An order for ceftazidime 675 mg IVPB q 8 hrs for a child weighing 32 lbs arrives at the pharmacy. The recommended dose of ceftazidime is 30-50 mg/kg IV q 8 hours. The label reads: For a 1 g vial, mix with 5 mL sterile water for a resulting concentration of 180 mg/mL. a) is this a safe dose? b) how many mL of a 1g vial will you ye for preparation?A patient, whose weight is 80.5 kg and height is 63 inches, is to receive dacarbazine in 250 mL 5% dextrose injection over 30 to 60 minutes. Dacarbazine is available as 200 mg/vial reconstituted to 10 mg/mL. How many mL will be needed to add to the IV bag?
- Available cloxacillin 2g match the following reconstitution option with the order ordered: 1500 mg of cloxacillin IV q8h ordered: 800 mg of cloaxacillin IM q6h ordered: 500 mg of cloxacillin IM q8h ordered: 1800 mg of cloxacillin IV q8h 1. 2. add 4.8 mL sterile water for concentration of 400mg/mL add 9.8 mL of sterile water for concentration of 200 mg/mLCalculate how much you need for the following dosages 36 You have haloperidol injection 5 mg in 1 mL; amount required = 6 mg. 37 You have diazepam suspension 2 mg in 5 mL; amount required = 5 mg. 38 You have codeine phosphate syrup 25 mg in 5 mL; amount required = 30 mg. 39 You have co-trimoxazole injection 480 mg in 5 mL; amount required = 2,040 mg. What volume and how many ampoules do you need?Acute lymphatic leukemia can respond well to methotrexate given 2 1/2 mg per kilogram every 14 days by IV rounding to the nearest whole number. What would be the appropriate dosage of methotrexate to administer biweekly to a patient weighing 110 pounds?