Which of the following statements best explains why the activity of ATP-citrate lyase and malic enzyme are often paired together? The use of ATP by ATP-citrate lyase means that NADH needs to be regenerated cytosolically so that more ATP can be generated via shuttle systems and replace the ATP used by ATP-citrate lyase ATP-citrate lyase produces ATP and malic enzyme produces NADPH, both needed in the fatty acid biosynthetic pathway The activity of ATP-citrate lyase and malic enzyme never are correlated, they always function in different realms of metabolism The generation of acetyl CoA is a substrate for fatty acid synthesis in the cytosol and NADPH is generated as the anabolic electron carrier

Which of the following statements best explains why the activity of ATP-citrate lyase and malic enzyme are often paired together? The use of ATP by ATP-citrate lyase means that NADH needs to be regenerated cytosolically so that more ATP can be generated via shuttle systems and replace the ATP used by ATP-citrate lyase ATP-citrate lyase produces ATP and malic enzyme produces NADPH, both needed in the fatty acid biosynthetic pathway The activity of ATP-citrate lyase and malic enzyme never are correlated, they always function in different realms of metabolism The generation of acetyl CoA is a substrate for fatty acid synthesis in the cytosol and NADPH is generated as the anabolic electron carrier

Biochemistry

6th Edition

ISBN:9781305577206

Author:Reginald H. Garrett, Charles M. Grisham

Publisher:Reginald H. Garrett, Charles M. Grisham

Chapter27: Metabolic Integration And Organ Specialization

Section: Chapter Questions

Problem 20P: Figure 27.3 illustrates the response of R (ATP-regenerating) and U (ATP-utilizing) enzymes to energy...

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