Which of the following groups of antimicrobial drugs selectively targets bacterial cell wall synthesis? beta-lactams quinolones sulfonamides polymyxins phenols
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Which of the following groups of antimicrobial drugs selectively targets bacterial cell wall synthesis?
beta-lactams
quinolones
sulfonamides
polymyxins
phenols
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- Technically speaking, which antimicrobial drugs are produced naturally? Biofilms Antibiotics Semisynthetics Syntheticslist 4 families of antimicrobials that belong to the beta-lactam groupIdentify a correct statement about tetracyclines. Multiple Choice They have a narrow antibacterial spectrum. They are bactericidal in nature. They bind irreversibly to bacterial ribosomes to inhibit bacterial protein synthesis. Their widespread use has allowed the emergence of bacterial resistance.
- What bacterial structural target would make an antibacterial drug selective for gram-negative bacteria? Provide one example of an antimicrobial compound that targets this structure.What was the first synthetic antimicrobial? - Salvarsan - Tetracycline - SulfonimideWhich antimicrobial agents have the narrowest spectrum of action? antivirals antifungals beta-lactams sulfanilamidesBottom of Form Penicillin is a narrow spectrum antibiotic because it only affects bacteria with mycolic acid in its cell wall, such as Mycobacterium tuberculosis. it only affects viruses it only affects Gram-negative organisms it only affects Gram-positive organismsBottom of Form Which of the following antibiotics might be destroyed by beta-lactamase enzymes? amphotericin B and ciprofloxacin streptomycin penicillin ciprofloxacinBottom of Form Which is incorrect about how the pharmaceutical industry has discovered drugs over the past 100 years? The process of discovery has involved custom-designing chemical compounds that we know will bind to target enzymes. The process of discovery has involved screening for chemicals that are toxic to bacteria while being less toxic to human cells. The process of discovery has involved screening thousands of randomly…
- Explain what type of antimicrobial hand gels-alcohol or triclosan-you would recommend people use in their daily lives.The type of antimicrobial drug that would be most likely to have toxic effects in humans based on the premise of selective toxicity when treating microbial infection would be a drug that O 1) inhibits the synthesis of the cell wall O 2) inhibits metabolic pathways O 3) disrupts the cytoplasmic membrane 4) inhibits protein synthesis 5) All of the above have equal potential to be toxicessential oils have been studied as potential antimicrobial agents. These naturally occuring compounds are linked to having the following type of activity in clinical trials: virucidal, septicidal, bactricidal, fungicidal
- Which of the following is a true statement about the aminoglycosides? Multiple Choice They are a group of bacteriostatic antibiotics. Their antibacterial spectrum mainly includes gram-positive bacilli. They are active against anaerobic organisms. They cause irreversible inhibition of bacterial protein synthesis.CHOICES: Isoniazid Rifampicin Ethambutol None of the Choices Requires Pyridoxine supplementation Ototoxic antitubercular drug Disrupts cell membrane transport Example of drug used in continuation phase Inhibits arabinosyl transferase required in cell wall assemblyWhat are the 4 main targets of antimicrobials? Provide the rationale why each is a good target.