Which drug factor will increase removal of drug through dialysis? a. High Molecular Weight b. High Lipophilicity c. High Hydrophilicity d. High Protein Binding
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Which drug factor will increase removal of drug through dialysis?
a. High Molecular Weight
b. High Lipophilicity
c. High Hydrophilicity
d. High Protein Binding
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Solved in 3 steps
- Atorvastatin: Elimination constant Bioavailability Volume of distribution Half-life ClearanceTABLE COMPLETION. Provide the necessary details in the table below. Number of Stopper Color Additive(s) Additive Mechanism of Action Inversions 2. 1. Red Zero *Glass tube 4. 3. K3EDTA in liquid form Eight 7. 8-9. 5-6. Gray In 13. 10. Red/gray and gold 15. Heparin Inhibits thrombin formation, K2EDTA binds calcium 14. Sodium Heparin and K2EDTAFor a lipid-soluble drug that has very poor aqueous solubility, what strategies could be used to make this drug more bioavailable after oral administration? This under Bipharmaceurics and Pharmacokinetics subject
- Half strength diatrizoate sodium. With 30 ml and a 50 cc syringe . How much of the medication and how much normal saline will addA and B. explanations to the solutions too please. thanksThe active drug substance given above contains a carboxylic acid group. Ionizable proton of carboxylic acid (circled in red taken), the pKa value is given as 3.5. This drug must be absorbed through the plasma membrane to pass. The speed of passage through the plasma membrane depends on the polarity of the molecule. Charged and polar molecules are slower than the membrane, neutral and hydrophobic molecules pass more rapidly. Your stomach Its pH is about 1.5 and the pH of the small intestine is about 6.0. whether this drug passes through the stomach or small intestine more into the blood. you wait Explain. In order to get full points, the ionic molecule in the stomach and intestines Compare them in terms of charge and polarity, indicating their state.
- G.What concentration of imidazole do you expect after you dialyze 1 mL of a sample containing 500 mM imidazole into 100 mL of dialysis buffer containing no imidazole? What if you repeat the process by moving the dialysis cassette to a fresh 100 mL of dialysis buffer?Read this article and answer the following question There are 3 different Metformin ER products available: Glucophage XR Glumetza ER Fortamet ER All 3 formulations are available generically but they are not interchangeable as they all use different release mechanisms. Glucophage XR uses a dual hydrophilic polymer system. The drug is slowly released by diffusing through a gel matrix, also known as GelShield diffusion system. Once the tablet is swallowed, the outer layer of the tablet forms a gel layer and the metformin contained within is slowly released. Due to this release mechanism, Glucophage XR can not be cut or split. Glumetza ER uses a mechanism known as gastro-retentive technology (also known as 'Modified Release'). The tablets are designed to remain in the stomach and deliver metformin to the upper GI tract over an extended period of time. Like Glucophage XR, Glumetza ER can not be cut or split. Fortamet ER uses single-composition osmotic technology (SCOT). After…