What would happen if the retinoblastoma protein wasn't able to bind to the E2F transcription factor?

Q: Match the gene name with the gene description. rb BRCA-1 A. tumor suppressor - p53 B. proto-oncogene…

A: Cancer is a condition caused by mutation in the genome that results in infinite cell multiplication…

Q: by Transcription Factor IID (TF IID)

A:

Q: What is IGF and what is its function?

A: Chemical messengers are the substances that serve to affect the target cells or tissues.

Q: Why is the differentiation of oocytes a great model for studying protein localization?

A: Protein localization is a process in which proteins gets accumulated in any particular location to…

Q: Cancer-promoting mutations are likely to have different effects on the activity of proteins encoded…

A: Cancer is the unnatural and excessive proliferation of cells that becomes harmful to normal body…

Q: What is Interleukin 1 (IL-1)?

A: The immune system has a vital role in protecting the body from outside pathogens (bacteria, viruses,…

Q: Why do signals indicating damage to cells result in increase in the expression of p21Cip1?

A: Cell cycle progression is tightly controlled by cyclins and cyclin-dependent kinases (CDKs), the…

Q: Part of the Ras protein is associated with the plasma membrane, and part extends into the cytoplasm.…

A: Ras are a family of small GTPases that are involved in signal transduction part of the cell…

Q: Identify the two general functions of the proteins encoded bytumor-suppressor genes.

A: Gene is the unit of heredity that is transferred from a parent to offsprings. Proto-oncogenes are…

Q: Binding of epithelial growth factor (EGF) to its receptors will result in Ras A) shutting down cell…

A: .A gene that controls cell proliferation and can function as a transcription factor, growth factor,…

Q: List the Pol II general transcription factors.

A: Transcription factors is a protein that controls the rate of transcription of gentic information…

Q: What would be the effect of a drug that altered the structure of allolactose so that it was unable…

A: Lac operon is defined as an operon which is required for the metabolism and transport of lactose…

Q: RIPK3 is a key modulator of necroptosis that

A: Necroptosis- The programmed form of necrosis or inflammatory cell death is called necroptosis.…

Q: Match the gene on the left with the gene category on the right.…

A: Genes  Genes are the information coded in a DNA. They make our protein and enzyme. They are…

Q: How does each of these small GTP-binding proteins contribute to the regulation of cell migration?

A: GTP bonding protein also known as G protein.G protein is present in eukaryotic and classifieds into…

Q: The following location is where the cell bodies of GSEs are located: select one: a b c d e f g h

A: Answer: Introduction: In spinal cord, somatic efferent neurons (GSE) also called as somatic motor,…

Q: Describe in detail each of the following proteins and their role in the cellular processes that they…

A: i. Ras Protein:  Describe: Ras is a family of related proteins that are expressed in all animal cell…

Q: Excess glucose in the body is converted to ----

A: When there is an unnecessary measure of sugar accessible in the blood it is taken up into the cells…

Q: I understand how nuclear factor-kB (NFKB) works in the inflammatory response but what is the…

A: Nuclear factor-κB (NF-κB), a transcription factor that is essential for inflammatory responses, is…

Q: Why is the biological activity of the v-Src protein so different from that of c-Src?

A: Src is also called a proto-oncogene. It is a non-receptor tyrosine kinase. It phosphorylates…

Q: What is Drosophila Mhc gene ?

A: A gene is the essential physical and functional unit of heredity. They are comprised of DNA…

Q: Define the following terms: a. cell transformation b. oncogene c. apoptosis d. early response gene…

A: Gene regulation is the mechanism that acts to induce or repress the expression of the gene.that…

Q: What occurs when the JAK-STAT pathway is activated?

A: The JAK/STAT pathway is a cell signaling pathway. The JAK are a category of proteins belonging to…

Q: 1- - C. IL-05 B. D. E. Bat 2 A. Name this signaling. Label:

A: Cell signalling can be divided into four types based on the distance the signals travels to reach…

Q: What intracellular signaling pathway is activated by Ras GTPase?

A: The Ras protein family members belong to a class of protein called small GTPase. They are involved…

Q: Order the listed proteins in the correct order so that cell proliferation is activated as the…

A: HGF stimulates epithelial cell proliferation, motility, morphogenesis via tyrosine phosphorylation.…

Q: What is Interleukin 2 (IL-2)?

A: The immune system is actively involved in preventing pathogens and other foreign particles from…

Q: When glucose is low and CAMP is present, CAMP's role is to. Activate catabolite activator protein…

A: Ans-When glucose is low and CAMP is present, CAMP's role is to-Activate catabolite activator protein…

Q: Is there non-functional leukopoiesis in Leukemoid Reaction

A: Answer: Leucocytes or leukocytes are the cells found in blood which are responsible for protecting…

Q: Would the following alterations to Src be oncogenic? Explain. (a) The deletion or inactivation of…

A: Src is a protooncogene.

Q: This asymptomatic disorder, typically discovered accidentally, is caused by mutations in the SLC36A2…

A: Both the mutations are associated with Iminoglycinuria

Q: Which glucose transporter is affected by the increased AKT signaling in tumor cells?

A: Tumour cells have a high metabolic turnover. Hence they need high amounts of glucose to sustain high…

Q: What is the largest family of cell surface receptors (>1% of the human genome)?

A: Cell surface receptors are transmembrane proteins embedded into the plasma membrane which play an…

Q: Explain why the continually active CDK will most likely change the normal cells into cancer cells.

A: The cell cycle is a series of events through which cells divide and produce daughter cells. It is…

Q: Please explain the regulatory role of Bcl-2 family proteins in cell death?

A: BCL-2 family proteins are the controllers of apoptosis, yet additionally have different functions to…

Q: Herceptin is an antibody that is used to treat certain forms of breast cancer by binding to a class…

A: Introduction:   Breast cancer is the uncontrollable growth of cells in the breast region. Two major…

Q: Choose the item in column 2 that best matches each item in column 1.…

A: A number of genes are implicated in cell proliferation and differentiation. Tight management of this…

Q: During cytokinesis, a _________________ pulls the cell surface inward, thereby forming a…

A: There are two types of cell division, mitosis, and meiosis. Mitosis occurs in somatic cells, and…

Q: What is the difference between Prima-1 and nutlins in the way they would fight cancer?

A: Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread…

Q: The proteins work together to cause the release of the transcription factor that is bound by the…

A: Tumor suppressor genes are for controlling and stopping the growth of cancerous cells. They inhibit…

Q: Explain with specific examples how oncogenic receptors would promote cellular proliferation in the…

A: Oncogenes are genes which are present in almost all eukaryotic cells especially in higher animals,…

Q: What is known as Src phosphorylates ZBP1 ?

A: Introduction: The localization of beta-actin messenger RNA to the sites of active actin…

Q: which is the case only in the context of a robust gene regulator network that maintains the…

A: Genes are the functional unit of DNA (deoxyribonucleic acid). They contain instructions for protein…

Q: What is this survival signal?

A: Survival signaling is usually concerned with blocking the survival signals of the cancer cells.…

Q: List the three 'effector' signaling pathways activated by the Ras protein.

A: Ras protein is a low-molecular-weight GDP/GTP-binding guanine triphosphatase encoded by the Ras…

Q: FceRI binds     A. IgA   B. IgG   C. IgE   D. Innocuous substances

A: “Since you have asked 2 questions, we will solve the first question for you. If you want any…

Gene Interactions

When the expression of a single trait is influenced by two or more different non-allelic genes, it is termed as genetic interaction. According to Mendel's law of inheritance, each gene functions in its own way and does not depend on the function of another gene, i.e., a single gene controls each of seven characteristics considered, but the complex contribution of many different genes determine many traits of an organism.

Gene Expression

Gene expression is a process by which the instructions present in deoxyribonucleic acid (DNA) are converted into useful molecules such as proteins, and functional messenger ribonucleic (mRNA) molecules in the case of non-protein-coding genes.