What is the mechanism dendritic cells use to deliver the message about a specific pathogen to the adaptive immune system? (Start from the point where the dendritic cell first encounters the pathogen and end when the message is delivered to a lymphocyte.)
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What is the mechanism dendritic cells use to deliver the message about a specific pathogen to the adaptive immune system? (Start from the point where the dendritic cell first encounters the pathogen and end when the message is delivered to a lymphocyte.)
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- 1) According to the video, what is another name for the innate immune sys and what does this system do? 2) According to the video, what causes inflammation and what cells cause it? 3) According to the video, what happens to neutrophils after they consume a pathogen? 4) According to the video, natural killer cells; what do they do? 5) The adaptive/acquired immune system can tell the difference between types of pathogens: true or false? 6) According to the video, helper t- function: 7) According to the video, cytotoxic t cells function: 8) According to the video, memory cells function:Some strains of the human papilloma virus (HPV) are resistant to interferons. If HPV can inhibit interferon binding to cells, what advantage does this give the virus? Question 2 options: Antiviral proteins will not be synthesized in neighbouring cells. Interferons will be released by non-infected neighbouring cells. Interferons will bind to the virus to neurtralize it. Interferons tell the virus-infected cells to apoptose. The viruses will be warned that a host is coming.How many types of “foreign molecules” (use the proper term where needed) does each cell recognize? On the pathogen side – what molecules will be recognized by these immune cells? (no need for specific names, just a few examples of pathogen molecules that will trigger an immune response) Bloodwork indicates that a patient who has pneumonia is actively secreting different forms of antibody against Streptococcus pneumoniae. Explain how the patient can respond to this pathogen by secreting more than one antibody.
- Correctly order the steps in cellular Immunity. Below is a sequence of events. Place them in the order they should occur, number 1 being the first item. Select the step number from the drop down next to each item. Items to order: a) .Cytotoxic T cell (CTL) recognizes the infected host cell b) The CTL secretes perforin and granzyme, causing apoptosis c) The CTL interacts with epitope presented by MHC-I on the dendritic cell d) The helper T cell activates the CTL cellWhich of the following is NOT an example of non- specific (innate) resistance mechanisms interacting directly with specific acquired immunity mechanisms? Complement being activated by antigen- antibody binding Macrophages and dendritic cells presenting antigens to lymphocytes Antibodies binding to bacterial surface antigens, coating (opsonizing) the bacteria and enhancing their phagocytosis by leukocytes None of the other four answers (All are examples of interaction between innate and acquired resistance) Antibody-dependent cell-mediated cytotoxicityOnce the antigen presenting cell delivers the message about the identity of the specific pathogen to the adaptive immune system, what is the mechanism of lymphocyte activation to make sure lymphocytes target that specific pathogen or toxin (Specificity)? Why does this process create a slow response during the first exposure of a pathogen?
- The circulating cytokines that recruit large numbers of phagocytes to the area of inflammation, resulting in pus, are called: O1) pyogens O 2) pyrogens 3) interferons O 4) defensinsFigure shows a series of events for the response in innate immune defense. a)State ONE main event happening in J in fighting pathogens. b)Natural killer cell has the ability to kill virus-infected cells and tumour cells rapidly. How do natural killer cells in event K recognise and kill these cells?The correct order of words to describe how innate immune response responds to a pathogen that has gotten by the physical and chemical barriers is: À) Skin, Saliva, Cytokines, Macrophage B)Macrophage, Cytokines, Neutrophil, Natural Killer Cell C) Neutrophil, Cytokines, Killer T Cell, Antibodies D) Antigen, Macrophage, B Cell, Killer T Cell
- Name two cytokines that are thought to be involved in the inflammatory response to viruses (cite your source). Describe a component of the innate immune response to viral infection (name it and explain how it works. Be sure you are talking about something that protects you from viruses.)Although the adaptive immune system has two arms, it has been said, “no T cells, no immunity.” Explain.The classical complement pathway is initiated by C1q binding to the surface of a pathogen. In some cases, C1q can directly bind the pathogen, for instance by recognizing proteins of bacterial cell walls, but in most cases C1q binds to IgM antibodies that are bound to the pathogen surface. How does this IgM-binding feature of C1q contribute to rapid, innate immune responses rather than to slow, adaptive responses? C1q induces B lymphocytes to begin secreting antibody within hours of pathogen exposure. Natural antibody that binds to many microbial pathogens is produced prior to pathogen exposure. C1q binds to C-reactive protein which then binds to IgM on the pathogen surface. C1q directly induces inflammation, recruiting phagocytes and antibodies from the blood into the infected tissue. C1q binds to dendritic cells in the infected tissue, inducing them to secrete inflammatory cytokines.