What is the difference between F+ and HFR?
The process by which a bacterium transfers its genetic material to another bacterium through direct contact is known as conjugation. The bacterium that donates the genetic material is known as the donor and the other one is known as recipient. A bacterium needs to have a DNA sequence called the fertility factor to be a donor genome.
The bacterial cells carrying the F plasmid are called F+ and those lacking the F plasmid are called F-, where F stands for “fertility factor”. During conjugation, the F factor is transferred to F- cell from the F+ cell, and now the F- cell becomes F+ cell. The HFR stands for high-frequency recombinant and is formed from the F+ strain. It transfers the entire genomic DNA.
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