Various types of vesicle coats have been implicated in membrane traffic pathways such as endocytosis, export from the ER to the Golgi, and transport between Golgi cisternae. But so far, no coat has been identified for the secretory vesicles that carry material from the Golgi to the plasma membrane. Do you think such a coat is likely to exist? Justify your answer.

Various types of vesicle coats have been implicated in membrane traffic pathways such as endocytosis, export from the ER to the Golgi, and transport between Golgi cisternae. But so far, no coat has been identified for the secretory vesicles that carry material from the Golgi to the plasma membrane. Do you think such a coat is likely to exist? Justify your answer.

Human Physiology: From Cells to Systems (MindTap Course List)

9th Edition

ISBN:9781285866932

Author:Lauralee Sherwood

Publisher:Lauralee Sherwood

Chapter3: The Plasma Membrane And Membrane Potential

Section3.3: Overview Of Membrane Transport

Problem 1CYU

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Various types of vesicle coats have been implicated in membrane traffic pathways such as endocytosis, export from the ER to the Golgi, and transport between Golgi cisternae. But so far, no coat has been identified for the secretory vesicles that carry material from the Golgi to the plasma membrane. Do you think such a coat is likely to exist?
IN the figure for D: The organization of a protein that normally resides in the plasma membrane in shown in the figure below. The boxes labeled 1,2 3 and 4 represent membrane-spanning sequences and the arrow represents a site of action of signal peptidase. Given this diagram, which of the following statements must be true? (C) (D) oplasmic Reticulum The N-terminus of this protein is in the ER lumen The mature version of this protein will span the membrane twice, with both the N- and C-terminus in the cytoplasm. Two of the answers are correct The C-terminus of this protein is in the ER lumen
Explain how the chemical composition/structure of the plasma membrane allows for it to be selectively permeable. What does this information tell you about the chemical composition of an integral protein versus a peripheral protein? How do these differences allow for their different functions?
What would happen in each of the following cases where something related to intracellular transport is altered? Assume in each case that the protein involved is a soluble protein, not a membrane protein. State where each protein would be located and explain each of your answers. You add a signal sequence (for the Golgi) to the N-terminal end of a normally cytosolic protein. You change the hydrophobic amino acids in an ER signal sequence into other, hydrophobic, amino acids.
Describe two different ways that integral membrane proteins associatewith a membrane. How do peripheral membrane proteins associate witha membrane?
Which of these answers explains why synaptic vesicles only releasee their neurotransmitter cargo in response to a signal? A) the necessary Rab proteins are not synthesized until an action potential arrives B) vesicle formation at the trans-Golgi network cannot occur in the absence of plasma membrane depolarization C) an additional protein, synaptotagmin, makes vesicle fusion dependent on the calcium concentration D)a plasma membrane transporter is needed to actively pump neurotransmitter into the synaptic cleft. These are inactive until membrane depolarization
What are the three types of coated vesicles involved in membrane trafficking. Name three types and briefly explain their role in the transport of material
Microtubules are important for transporting cargo in nerve cell axons, as diagrammed in Figure Q17- 33. Notice that the two types of cargo are traveling in opposite directions. Which of the following statements is likely to be false? cell body microtubule axon Figure Q17-33 inward transport axon terminal The black cargo and the gray cargo require ATP hydrolysis for their motion. The gray cargo is attached to dynein. outward transport The black cargo and the gray cargo are moving along microtubules of opposite polarity. The black cargo moving toward the axon terminal contains a domain that specifically interacts with the tail domain of a particular kind of motor.
Which is the definition of 'retrograde' with respect to membrane trafficking? movement from the endosome to the lysosome movement from the ER to the Golgi to either the plasma membrane or the endosome/lysosome movement from the cytoplasm to the nucleus movement from the Golgi to the ER
Vesicle transport occurs between the ER and the Golgi in bothdirections. Let’s suppose a researcher added a drug to cells thatinhibited vesicle transport from the Golgi to the ER but did not affectvesicle transport from the ER to the Golgi. If you observed cellsmicroscopically after the drug was added, what would you expect to seehappen over the course of 1 hour?a. The ER would get smaller, and the Golgi would get larger.b. The ER would get larger, and the Golgi would get smaller.c. The ER and Golgi would stay the same size.d. Both the ER and Golgi would get larger.e. Both the ER and Golgi would get smaller
The uneven distribution of ions across the plasma membrane is regulated, in part, by transport proteins. The result is a net negative charge on the inside of the plasma membrane and a net positive charge on the outside of the plasma membrane. How doyou explain the net negative charge inside the plasma membrane when the predominant intracellular ion is K+?
Cells transporting substances across their membranes is essential. Choose TWO of the following types of cellular transport. ๏osmosis ๏active transport ๏facilitated diffusion ๏endocytosis / exocytosis (a)For each type of transport you choose, describe the transport process. Explain how the organization of cell membrane plays a role the movement of specific molecules across membrane. (b)Using the same transport types, identify a specific cell that utilizes that type of transit (i.e. one cell for each transport type, or two different cell examples), and detail a substance that is transferred. (c)A typical human lymphocyte has a radius of about 10 μm, while a typical bacterium (e.g., S. pneumoniae) has a radius of about 1 μm. Assuming that both cell types are perfectly spherical, compare and contrastthe transport mechanisms for each of these cells.