Inorganic compounds of metallic mercuryare presumed from metabolic studies todistribute uniformly after inhalation oringestion with 8% going to the liver and 92%to the total body. Biological clearance ofmercury in each of these tissues occurs bytwo compartments, 95% with a biologicalhalf-life of 40 days and the remaining 5%with a biological half-life of 10,000 days. Foran intake of 1 MBq of 203Hg (Tr= 46.61 d).Determine the following1. Total number of transformations inthe Liver.2. Total number of transformations inthe total body.

Total number of transformation of the metallic merury defines the cumulative activity of metallic…

Answered: Total number of transformations in the…

Science

Biochemistry

Total number of transformations in the Liver. Total number of transformations in the total body.

Human Physiology: From Cells to Systems (MindTap Course List)

9th Edition

ISBN:9781285866932

Author:Lauralee Sherwood

Publisher:Lauralee Sherwood

Chapter11: The Blood

Section: Chapter Questions

Problem 1SQE

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Question

Inorganic compounds of metallic mercury
are presumed from metabolic studies to
distribute uniformly after inhalation or
ingestion with 8% going to the liver and 92%
to the total body. Biological clearance of
mercury in each of these tissues occurs by
two compartments, 95% with a biological
half-life of 40 days and the remaining 5%
with a biological half-life of 10,000 days. For
an intake of 1 MBq of 203Hg (Tr= 46.61 d).
Determine the following
1. Total number of transformations in
the Liver.
2. Total number of transformations in
the total body.

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