There are dozens of common variations of the c-myc gene, which are associated with different types of cancer. Here are 3 variations of part of a sequence of the c-myc gene, located between nucleotides 180 and 201. The original sequence is given to you, as well as the sequences of 3 variations. The mutated nucleotide of each variation is annotated in gray. Use this information (picture) to answer the next two (2) questions  1. Which of the c-myc variations is least likely to cause a change in c-myc function? 2. Which variation of c-myc produces a nonsense mutation?

Basic Clinical Laboratory Techniques 6E
6th Edition
ISBN:9781133893943
Author:ESTRIDGE
Publisher:ESTRIDGE
Chapter2: Basic Hematology
Section2.3: Microhematocrit
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There are dozens of common variations of the c-myc gene, which are associated with different types of cancer. Here are 3 variations of part of a sequence of the c-myc gene, located between nucleotides 180 and 201. The original sequence is given to you, as well as the sequences of 3 variations. The mutated nucleotide of each variation is annotated in gray. Use this information (picture) to answer the next two (2) questions 

1. Which of the c-myc variations is least likely to cause a change in c-myc function?
2. Which variation of c-myc produces a nonsense mutation?

Originale: 180 — CGG TСА ААС TGT GCA CCG GAG
201
-
Variation 1:180
CGG TCA ААТ TGT GСА СCG GAG
201
-
Variation 2:180
CGG TCA ААС TGT GCА CGG GAG — 201
-
Variation 3: 180
CGG TCA ААС TGA GCA CCG GAG — 201
Transcribed Image Text:Originale: 180 — CGG TСА ААС TGT GCA CCG GAG 201 - Variation 1:180 CGG TCA ААТ TGT GСА СCG GAG 201 - Variation 2:180 CGG TCA ААС TGT GCА CGG GAG — 201 - Variation 3: 180 CGG TCA ААС TGA GCA CCG GAG — 201
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