The solubility of CO2 in blood is about 0.062 mL dL-1 mmHg-1. Arterial blood has a Pa_CO2 = 40 mm Hg and venous blood has PV_CO2 = 46 mm Hg, and cardiac output is 5 L min-1. A. Calculate the content of dissolved CO2 (in mL dL-1) in arterial and venous blood and how much CO2 is removed from the tissues and delivered to the lungs per minute. (Hint: CO2 content = solubility of CO2 * PCO2) (Hint: Rate of CO2 transport = cardiac output * (arterial CO2 content – venous CO2 content) B. If the volume diffusion rate of CO2 = 200 mL min-1 in the lung, what fraction of the total CO2

Cardiopulmonary Anatomy & Physiology
7th Edition
ISBN:9781337794909
Author:Des Jardins, Terry.
Publisher:Des Jardins, Terry.
Chapter15: Hemodynamic Measurements
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The solubility of CO2 in blood is about 0.062 mL dL-1 mmHg-1. Arterial blood has a Pa_CO2 = 40 mm Hg and venous blood has PV_CO2 = 46 mm Hg, and cardiac output is 5 L min-1. A. Calculate the content of dissolved CO2 (in mL dL-1) in arterial and venous blood and how much CO2 is removed from the tissues and delivered to the lungs per minute. (Hint: CO2 content = solubility of CO2 * PCO2) (Hint: Rate of CO2 transport = cardiac output * (arterial CO2 content – venous CO2 content) B. If the volume diffusion rate of CO2 = 200 mL min-1 in the lung, what fraction of the total CO2 removal is accomplished through carrying dissolved CO2? C. Describe the effects of increased P CO2 and H+ concentration on the oxygen-hemoglobin dissociation curve. How are these effects adaptive for oxygen unloading in the tissues?
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