the Mode of Inheritance (MOI) exercises. Focus on determining the values in the colored cells. Your solutions should read as prose, not simply computations. I have provided values for two MOIs discussed in the lecture, Autosomal Dominant MOI, and X-linked Recessive where the father is affected and the mother is homozygous unaffected. Sometimes, there is confusion regarding defining the disease allele and wild-type allele for a specific mode of inheritance. In this worksheet, you'll note that the D allele is the disease allele for the Autosomal Dominant mode of inheritance. However, it is also the disease allele for the Sex-Linked Recessive mode of inheritance, where the father is affected. The point is, any letter or symbol can represent a disease allele or wild-type allele as long as you define its meaning. For example, I may user to be the disease allele in an Autosomal Recessive mode of inheritance, and R to be the wild-type allele, or vice versa, as long as I write something like: r = disease allele, R = Wild-type allele.
the Mode of Inheritance (MOI) exercises. Focus on determining the values in the colored cells. Your solutions should read as prose, not simply computations. I have provided values for two MOIs discussed in the lecture, Autosomal Dominant MOI, and X-linked Recessive where the father is affected and the mother is homozygous unaffected. Sometimes, there is confusion regarding defining the disease allele and wild-type allele for a specific mode of inheritance. In this worksheet, you'll note that the D allele is the disease allele for the Autosomal Dominant mode of inheritance. However, it is also the disease allele for the Sex-Linked Recessive mode of inheritance, where the father is affected. The point is, any letter or symbol can represent a disease allele or wild-type allele as long as you define its meaning. For example, I may user to be the disease allele in an Autosomal Recessive mode of inheritance, and R to be the wild-type allele, or vice versa, as long as I write something like: r = disease allele, R = Wild-type allele.
Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN:9781305251052
Author:Michael Cummings
Publisher:Michael Cummings
Chapter12: Genes And Cancer
Section: Chapter Questions
Problem 3CS: Mike was referred for genetic counseling because he was concerned about his extensive family history...
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