The father of two children is type O+, and the mother is type A+. The children are O- and A+. Given this information, what are the genotypes of the father vs. the mother at both the “I” and “Rh” alleles? Explain your rationale.
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The father of two children is type O+, and the mother is type A+. The children are O- and A+. Given this information, what are the genotypes of the father vs. the mother at both the “I” and “Rh” alleles? Explain your rationale.
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- Could an individual with blood type O (genotype ii) be a legitimate child of parents in which one parent had blood type A and the other parent had blood type B?A child has a blood type of “B positive”. This child is known to be a heterozygote at the ABO blood type gene and also a heterozygote at the Rh blood type gene. Select all of the choices below that show possible parents of this child.a) Genotypes IA IA X IA IAb) Genotypes IA IA X IA i c) Genotypes IA i X IA id) Genotypes IA IA X IA IBe) Genotypes IA IA X IB if) Genotypes IA IA X i ig) Genotypes IA i X i ih) Genotypes IA i X IB ii) Genotypes IB IB X IB IBj) Genotypes IB IB X IB ik) Genotypes IB IB X IA il) Genotypes IB IB X i im) Genotypes IB i X IB in) Genotypes IB i X i io) Genotypes IB IB X IA IBp) Genotypes IA IA X IB IBq) Genotypes IA IB X IA IBr) Genotypes IA IB X IA is) Genotypes IA IB X IB it) Genotypes IA IB X i iu) Genotypes i i X i iv) Genotypes + + X + +w) Genotypes + + X + -x) Genotypes + + X - -y) Genotypes + - X + -z) Genotypes - - X + -a1) Genotypes - - X - -Several genes in humans in addition to the ABO gene(I) give rise to recognizable antigens on the surface ofred blood cells. The MN and Rh genes are two examples. The Rh locus can contain either a positive or anegative allele, with positive being dominant to negative. M and N are codominant alleles of the MN gene.The following chart shows several mothers and theirchildren. For each mother-child pair, choose the fatherof the child from among the males in the right column, assuming one child per male.Mother Child Malesa. O M Rh(pos) B MN Rh(neg) O M Rh(neg)b. B MN Rh(neg) O N Rh(neg) A M Rh(pos)c. O M Rh(pos) A M Rh(neg) O MN Rh(pos)d. AB N Rh(neg) B MN Rh(neg) B MN Rh(pos)
- A woman who has blood type A positive has a daughter who is type O positive and a son who is type B negative. Rh positive is a trait that shows simple dominance over Rh negative and is designated by the alleles R and r, respectively. A third gene for the MN blood group has codominant alleles M and N. If both children are of blood type M in addition to their ABO blood type, list all of the possible parental phenotypes for the ABO, MN and Rh traits.This problem refers to the MN and ABO loci mentioned in class. It also refers to the Rh locus, which is responsible for the positive/negative part of the blood type. The Rh+ allele is dominant to the Rh- allele at this locus. Select all couples who could be the parents of a child with phenotype N, AB- based on the phenotypes at these three loci If none of these couples could be the parents of this child, select "None of These. Select one or more: Mother Type MN, B+ and Father Type N. O+ Ob Mother Type MN, AB- and Father Type M, O- Mother Type M, A+ and Father Type N, B- O d. None of These Mother Type MN, O+ and Father Type MN,A-A mother is heterozygous for the X-linked gene for colorblindness and also heterozygous for the autosomal inherited sickle cell anemia. She is married to a man who can see color normally and who is heterozygous for sickle cell trait. Using b (colorblind), B (normal color), S (normal hemoglobin), s (sickle cell), answer the following: a. What are the genotypes of the parents? b: What is the probability of having a child who is both color blind and has sickle cell anemia?
- In humans, the allele for normal blood clotting, H, is dominant to the allele for hemophilia, h. The trait is X-linked. A female hemophiliac has a child with a man who is not a hemophiliac. What is the probability that this couple's child is a hemophiliac and what is the child's gender? Your response must include a Punnett square with correct nomenclature.A child has a blood type of “B positive”. This child is known to be a heterozygote at the ABO blood type gene and also a heterozygote at the Rh blood type gene. Select all of the choices below that show possible parents of this child. Question 7 options: Genotypes IA IA X IA IA Genotypes IA IA X IA i Genotypes IA i X IA i Genotypes IA IA X IA IB Genotypes IA IA X IB i Genotypes IA IA X i i Genotypes IA i X i i Genotypes IA i X IB i Genotypes IB IB X IB IB Genotypes IB IB X IB i Genotypes IB IB X IA i Genotypes IB IB X i i Genotypes IB i X IB i Genotypes IB i X i i Genotypes IB IB X IA IB Genotypes IA IA X IB IB Genotypes IA IB X IA IB Genotypes IA IB X IA i Genotypes IA IB X IB i Genotypes IA IB X i i Genotypes i i X i i Genotypes + + X + + Genotypes + + X + -…O. 2 Hemophilia A is an X-linked trait where blood clotting is affected due to a mutation in a clotting factor protein. Georgio has hemophilia and attends a support group where he meets Gbenga, who does not have the disease, but whose father has hemophilia. Her mother is not affected. A) If they marry, what percentage % of all their children will have hemophilia? % B) Georgio meets another woman, Maria, at the hemophilia support group. Maria also lacks the trait, but her mother has hemophilia while her father is unaffected. # 3 Would a Georgio-Maria mating provide a larger chance of having afflicted children compared to a Georgio-Gbenga mating? C) Show how you came up with your answer to B. Edit View Insert Format Tools Table 12pt ✓ 80 F3 V Paragraph ✓ $ 4 Yes or No 000 000 F4 DO LO % 5 BIUAV T² | F5 ^ MacBook Air 6 2 F6 V & 7 F7 * 8 DII F8 ( 9 DD F9 1 0 S F
- Kara is B-positive and her father has A-negative blood. Kara marries Ryan, who is A-negative. Ryan’s father has O-positive blood. (e)What are the phenotypic ratios of blood types (for both the ABO gene and Rh gene) that would be expected among their children? (Show your work in a Punnett square below!)The mother of a family with 10 children has blood typeRh+. She also has a very rare condition (elliptocytosis,phenotype E) that causes red blood cells to be oval rather than round in shape but that produces no adverseclinical effects. The father is Rh− (lacks the Rh+ antigen)and has normal red blood cells (phenotype e). The children are 1 Rh+ e, 4 Rh+ E, and 5 Rh− e. Information isavailable on the mother’s parents, who are Rh+ E andRh− e. One of the 10 children (who is Rh+ E) marriessomeone who is Rh+ e, and they have an Rh+ E child.a. Draw the pedigree of this whole family.b. Is the pedigree in agreement with the hypothesisthat the Rh+ allele is dominant and Rh− is recessive?c. What is the mechanism of transmission ofelliptocytosis?d. Could the genes governing the E and Rh phenotypesbe on the same chromosome? If so, estimate the mapdistance between them, and comment on your resultA woman homozygous for normal height, with freckles, almond-shaped eyes, small nose, and Type A blood, has a Type O mother with no freckles and a type AB father with round eyes. She is engaged to a man with achondroplasia, round eyes and medium sized nose. Unlike his father, hismother is of normal height. Both his parents have Type O blood but nobody from both sides of his family has or had freckles. a. Write the COMPLETE genotypes of the man and the woman. Clearly indicate which genotype belongs to whom. b. Based on their genotypes, what is the probability that they will have: b.1 a child with Achondroplasia? b.2 a child of normal height? b.3 a child with type AB blood? b.4 a daughter with round eyes, freckles, and medium sized nose? b.5 a son with almond eyes, no freckles, and small nose?b.6 a daughter with same genotype as the woman? b.7 a son with same genotype as the man?
