The epinephrine signaling pathway plays a role in regulating glucose homeostasis in muscle cells. The signaling pathway is activated by the binding of epinephrine to the beta-2 adrenergic receptor. A simplified model of the epinephrine signaling pathway is represented in Figure 1. Adenylyl Cyclase Beta-2 Adrenergic Receptor Epinephrine `Cyclic AMP АТР Plasma Membrane GTP Protein Kinase A -АТР GDP GTP ►ADP GDP G Protein Phosphorylase Kinase -АТР ADP Glycogen Phosphorylase Glycogen Glucose-1-Phosphate Glycolysis Figure 1. A simplified model of the epinephrine signaling pathway in muscle cells

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