statement is true. Both statements are false. 1. Epigenetics does not consider how exposure to different environmental conditions can alter the DNA sequence. II. Nutrigenomics is the study of how diet and gene expression interact through molecular mechanisms. A. Only the first statement is true. B.Only the second statement is true. C. Both statements are true.
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- a. What is your epigenome (i.e. epigenetics)? b. Does lifestyle affect your epigenome? Explain c. Does your epigenome change with age? Explain d. What is epigenetic therapy? Is it working? Explain Edit View Insert Format Tools Table 12pt v Paragraph v BIUA 2v T? Addre DELLWhen chromatin is condensed, transcription cannot happen. Why not? RNA cannot access the promoter region of the gene DNA helicase cannot access the RNA strand RNA polymerase cannot access the DNA strand Transcription factors cannot access the termination region of the gene1. Methylation of DNA and acetylation of histones are directly correlated. 2. Histone demethylation and acetylation are both for gene inactivation. OA.Only the first statement is true. OB.Only the second statement is true. OC. Both statements are true. OD. Both statements are false.
- Please answer all questions if possible. 1. Why are genetic screens useful? Why do biologists do screens? What are we trying to do? What is the Big Picture purpose? 2. Why would a researcher be interested in over- or mis- expression phenotypes?a. What is your epigenome (i.e. epigenetics)? b. Does lifestyle affect your epigenome? Explain -c. Does your epigenome change with age? Explain d. What is epigenetic therapy? Is it working? Explain Edit View Insert Format Tools Table 12pt v Paragraph v в I Address DELL F7 F8 F9 F10 F1 F4 F5 F6 # % & 3 4 6. 7 8 9 Y ...3. Figure on the right shows a DNA Genes expressed microarray assay of gene in cancerous expression levels. In this tissue: Red microarray if a sample with normal tissue is labeled with Genes expressed in normal tissue: green fluorescent dye, and a Green sample with cancerous tissue is labeled with red, what colored Genes expressed in both tissues: spots would represent genes that you would be interested in if you Yellow were studying cancer? Explain. Genes expressed in neither tissue: Black
- 1. How are scientists able to realize their objectives in genetic engineering?2. Can you cite the techniques in genetic engineering scientists utilized in creating outcomes?. The website CBioPortal (http://www.cbioportal.org)is an exceptionally useful program for visualizing thecancer genes and genomes of tumors from thousandsof patients with different kinds of cancer that havebeen analyzed by whole genome sequencing and insome cases, by RNA-Seq.Go the the CBioPortal site and click All underSelect Cancer Study and in Enter Gene Set typePTEN, then hit Submit. On the page that is returnedyou will see how the coding region of the PTEN geneis altered in tumors investigated in the various studies.Hitting the tab Mutations will let you see the detailsof these mutations relative to the PTEN protein, whilethe tab Expression lets you see how the gene’s expression (in terms of cDNA reads) is altered in individual tumor samples.a. Is PTEN an oncogene or a tumor suppressor gene?What kinds of evidence lead you to this conclusion?b. What kinds of cancer are most likely to involvealterations of PTEN?c. How would you identify patients whose tumorcells are particularly…2. Watch the second video (13 minutes) about Epigenetics found here and answer the following questions: NOVA | Epigenetics STIR a. What is your epigenome (i.e. epigenetics)? b. Does lifestyle affect your epigenome? Explain c. Does your epigenome change with age? Exp d. What is epigenetic therapy? Is it working? Explain Edit View Insert Format Tools Table 12pt v Paragraph v U A Pc PrtScn F7 Home F8 End F9 F6 F3 F4 & 7 8 E Y K D F G H J 60
- 1. Define epigenetics in your own words. 2. Describe one epigenetic mechanism and the possible effects it has on an organism’s DNA.. Null alleles (mutant genes) produce no protein product. This is a genetic change. However, epigeneticallysilenced genes also produce no protein product. Howdoes one determine experimentally whether a genehas been silenced by mutation or has been silencedepigenetically?Transgenic mice and other model animals are used to study human neurodegenerative disorders to O produce tissues for transplantation O develop animals with desirable traits. produce genes for gene therapy. research molecular mechanisms of a human disorder. all of the choices are possible.