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Q: What does penicillin binding protein do?
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Q: How does the loss of the Adenomatous polyposis coli (APC) protein lead to the deregulation of…
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Q: Explain what is TFIID ?
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Q: A mutation that provides a bacterium with resistance to an antibiotic will be beneficial in…
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Resistance to many penicillins is the result of cell wall mutations in a variety of bacteria. True or false?
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- Explain what is TFIID ?Usually, bacteria only make tryptophan when tryptophan is absent or available in low concentration. However, a particular bacterial mutation makes tryptophan all the time whether or not tryptophan is present. What could explain this phenotype? A) the terminator hairpin is unable to form B) the antiterminator hairpin is unable to form C) trpE is mutated D) trpD is mutated E) trpA is mutatedThe ribosome is the target for many important antibiotics. These drugs must discriminate between bacterial and eukaryotic ribosomes to achieve drug specificity and toxicity. For the two common antibiotics below, what is their mechanism of action and why are they more toxic to bacteria than eukaryotes? a) Tetracycline b) Erythromycin
- Chlamydia are pathogenic bacteria that must be grown within a eukaryotic host cell. They rely on the host cell for many nutrients, including nucleotides, lipids, and amino acids. It is thus no surprise that when grown in co-culture with a host depleted of any of these metabolites, chlamydial growth declines. However, high levels of certain amino acids also inhibit chlamydial growth. Specifically, the amino acids leucine, isoleucine, methionine, and phenylalanine slow down the growth by inhibiting the amino acid transporter called BrnQ. On the other hand, if valine is present in the medium these amino acids have no effect on BrnQ. Discuss how this might be possibleWhy are structural analogs of sugar molecules (such as Oseltamivir and zanamivir) effective in treatment of influenza-virus infection?Why are proteins synthesised from spirulina called single cell anemia?
- With some level of toxic shock syndrome caused by the superantigen produced by Staphylococcus aureus, why the antibiotics are not effective after a certain point, even though the pathogen is susceptible to them?Why are proteins synthesized from Spirulina called Single celled Proteins? What is the significance of such a protein?Give two reasons why E. coli is naturally resistant to antibiotics like Penicillin?
- Most antibacterial drugs disrupt or destroy prokaryotic cellular structures or processes that are different than those of eukaryotic cells or may not even be present in eukaryotic cells. List and describe at least three prokaryotic cellular features that could be targeted to inhibit or kill a bacterial pathogen without harming its eukaryotic host.How does the loss of the Adenomatous polyposis coli (APC) protein lead to the deregulation of Beta-catenin functions in FAP patients?The peptidoglycan in bacterial cell walls is built in part by penicillin-binding proteins. (PBPs). What is the normal function of these PBPs?