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- Regulated reabsorption of Na+ at the DCT occurs under the influence of the hormone A renin B ΕΡΟ C ADH D aldosteroneIn response to hemorrhagic shock, the kidneys produce a small volumeof very concentrated urine. Explain how the rate of filtrate formationchanges and how Na+ transport is altered in the distal convoluted tubulein response to hemorrhagic shock.true or false Aldosterone is required to restore water from loop of Henle, and reabsorption of Na+ from this segment is increased by ADH, allowing equilibration of water with the hyperosmotic interstitium
- The reabsorption of water, Cl–, and glucose by the PCT islinked to the reabsorption of Na+, but in three very different ways. Contrast these three mechanismsSome tumors of the adrenal cortex secrete excess aldosterone and may cause paralysis. Explain this effect andidentify the electrolyte and fluid imbalances you wouldexpect to observe in such a caseDrugs that increase urine flow (diuretic drugs) are oftenemployed in the treatment of hypertension (high blood pressure)or other disease states. Three physiological categories of suchdrugs are ones that (i) function as loop diuretics, (ii) inhibitthe action of aldosterone, and (iii) block Na+ channels in thecollecting ducts. Explain why each of these categories wouldbe expected to increase Na+ excretion and urine flow. (Hint:Rereading the section on hormones at the end of Chapter 28might prove helpful.)
- Define renin-angiotensin-aldosterone mechanismIndicate whether the following sentence is True or False Aldosterone is required to restore water from loop of Henle, and reabsorption of Na+ from this segment is increased by ADH, allowing equilibration of water with the hyperosmotic interstitiumRenal tubules cannot reabsorb HCO3–; yet HCO3–concentration in the tubular fluid falls while in the blood plasma itrises. Explain this apparent contradiction.