Rank the nitrogen atoms in each compound in order of increasing basicity. Isoniazid is a drug used to treat tuberculosis, whereas histamine (Section 25.6B) causes the runny nose and watery eyes associated with allergies. NH2 NHNH2 b. а. isoniazid histamine
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- Rank the labeled nitrogen atoms in each compound in order of increasing basicity. Histamine causes the runny nose and watery eyes associated with allergies, and trazodone is a drug used as a sedative and antidepressant.Rank the nitrogen atoms in each compound in order of increasing basicity. Isoniazid is a drug used to treat tuberculosis, whereas histamine (Section 25.6B) causes the runny nose and watery eyes associated with allergies.Rank the compounds in each group in order of increasing basicity.
- Rank the labeled N atoms in the anticancer drug imatinib (trade name Gleevec) in order of increasing basicity. Imatinib, sold as a salt with methanesulfonic acid (CH3SO3H), is used for the treatment of chronic myeloid leukemia as well as certain gastrointestinal tumors.Rank the labeled N atoms in the anticancer drug imatinib (trade nameGleevec) in order of increasing basicity. Imatinib, sold as a salt withmethanesulfonic acid (CH3SO3H), is used for the treatment of chronicmyeloid leukemia as well as certain gastrointestinal tumors.Rank each set of compounds in order of increasing basicity.aniline, pyrrole, pyridine, piperidine
- 2)Rank the following in order of basicity and explain your choices.Rank the compounds in each group in order of increasing acidity.Answer the following questions about erlotinib and terbinafine. Erlotinib,sold under the trade name Tarceva, was introduced in 2004 for thetreatment of lung cancer. Terbinafine is an antifungal medication used totreat ringworm and fungal nail infections. Which C–H bond in erlotinib is most acidic? What orbitals are used to form the shortest C–C single bond inerlotinib?
- Rank the following compound in each group based on increasing basicityRank the bases below in order of increasing basicity.Decide which N atom in each molecule is most basic, and draw the product formed when each compound is treated with CH3CO2H. Zolpidem (trade name Ambien) is used to treat insomnia, whereasaripiprazole (trade name Abilify) is used to treat depression,schizophrenia, and bipolar disorders.