QUESTION 28 How can the issue encountenred in the previous problem be avaided? (Fa in the blark) Before a strong base is appled, we mui O Acivate the alcohol. O B. Perform a radical halogenation reacion O Deprotonate the alcohol d Reduce the alcohol. O Oidian the alcohol

Organic Chemistry
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Author:John E. McMurry
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Chapter17: Alcohols And Phenols
Section17.SE: Something Extra
Problem 60AP: Benzvl chloride can be converted into benzaldehvde by treatment with nitromethane and base. The...
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Question #28 needed

QUESTION 24
For problems 24-30, answer the questions about the 2 step resction sequence shown below.
Reaction 1
Intermediate
Product Y
Reaction 2
HO
What new funcional group is found In the final product?
3. Curbonyl
EAlcchol
C Akyne
d. Tet butylgroup
C.Alkene
Oapunsauraled.carbony
QUE STION 25
Dehydraion WILL NOT produce the desired product fromthe gnen starting material. See questions 20 23 for companson.) We need mare contral over the sterochemlatry to synthesize the comect produc, we need Io uBe an E2 reaction. In additon to a strong basE, whalt.other components does an E2 reaction require? Choose all that apply
OL Anantperiplanar.relaborship beween the leaving group and a HalEm.
OL Agoodlesving group
O L Agauche relabionship between the leaving group and a Hatom
ON An edipsed relalionship between the leaving group and aH alom.
OV Acuboesbion
QUE STION 26
Based on yor answer lo the previous prcblem, which conformation is needed lo produce the desired product through an E2 mechanism?
HC
H.C
ICHJ (H,C)CCH
HLG
H.
H,C H
(H,C),C CH,
LG CH,
H.
H LG
LG
(H,CCLG
CH,
QUE STION 27
The desired product WILL NOT form if a stirong base is appled to the starting material nght away in Reacion 1. Why does this synthelic route fail lO product the desired product?
Strong base
Incorrect
product
HO
3.The base wil deprotonate he acchol and foman epoxde product
b.An S 2 reaction will accur instead of an E2 reaction.
O The base will deprotonNte the alcohol and form an alkaxide productL
O d.Acbocabion rearrangement accurs.
QUE STION 28
How can the issue encountered in the previcus problem be avoided?
Fil in the blank.) Before a strong base is applied, we mu
OActivate the alcohol.
b.Periorm a radical halagenation resicion,
OC. Deproloale the alcchol.
d.Reduce the alcohol.
E.Oxidize the alcohol
Transcribed Image Text:QUESTION 24 For problems 24-30, answer the questions about the 2 step resction sequence shown below. Reaction 1 Intermediate Product Y Reaction 2 HO What new funcional group is found In the final product? 3. Curbonyl EAlcchol C Akyne d. Tet butylgroup C.Alkene Oapunsauraled.carbony QUE STION 25 Dehydraion WILL NOT produce the desired product fromthe gnen starting material. See questions 20 23 for companson.) We need mare contral over the sterochemlatry to synthesize the comect produc, we need Io uBe an E2 reaction. In additon to a strong basE, whalt.other components does an E2 reaction require? Choose all that apply OL Anantperiplanar.relaborship beween the leaving group and a HalEm. OL Agoodlesving group O L Agauche relabionship between the leaving group and a Hatom ON An edipsed relalionship between the leaving group and aH alom. OV Acuboesbion QUE STION 26 Based on yor answer lo the previous prcblem, which conformation is needed lo produce the desired product through an E2 mechanism? HC H.C ICHJ (H,C)CCH HLG H. H,C H (H,C),C CH, LG CH, H. H LG LG (H,CCLG CH, QUE STION 27 The desired product WILL NOT form if a stirong base is appled to the starting material nght away in Reacion 1. Why does this synthelic route fail lO product the desired product? Strong base Incorrect product HO 3.The base wil deprotonate he acchol and foman epoxde product b.An S 2 reaction will accur instead of an E2 reaction. O The base will deprotonNte the alcohol and form an alkaxide productL O d.Acbocabion rearrangement accurs. QUE STION 28 How can the issue encountered in the previcus problem be avoided? Fil in the blank.) Before a strong base is applied, we mu OActivate the alcohol. b.Periorm a radical halagenation resicion, OC. Deproloale the alcchol. d.Reduce the alcohol. E.Oxidize the alcohol
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ISBN:
9781305080485
Author:
John E. McMurry
Publisher:
Cengage Learning