Question 22 Congenital adrenal hyperplasia (CAH) are a group of heritable disorders associated with a deficiency in cortisol synthesis. The most common cause of CAH is a mutation in the adrenal 21-a-hydroxylase cytochrome P450 that converts progesterone to 17-hydroxyprogesterone. One of the serious complications is a salt wasting syndrome which results in large serum sodium losses. What effects on hormone levels would be expected? OA. ACTH is elevated and aldosterone is reduced OB. ACTH is reduced and aldosterone levels remain unchanged OC. Both ACTH and aldosterone levels are unchanged O D. ACTH is elevated and aldosterone is unchanged OE. ACTH is reduced and aldosterone is elevated

Human Anatomy & Physiology (11th Edition)
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Question 22
Congenital adrenal hyperplasia (CAH) are a group of heritable disorders associated with a deficiency in cortisol synthesis. The most common cause of CAH is a mutation in the adrenal 21-a-hydroxylase
cytochrome P450 that converts progesterone to 17-hydroxyprogesterone. One of the serious complications is a salt wasting syndrome which results in large serum sodium losses. What effects on hormone
levels would be expected?
OA. ACTH is elevated and aldosterone is reduced
OB. ACTH is reduced and aldosterone levels remain unchanged
OC. Both ACTH and aldosterone levels are unchanged
OD. ACTH is elevated and aldosterone is unchanged
OE. ACTH is reduced and aldosterone is elevated
Transcribed Image Text:Question 22 Congenital adrenal hyperplasia (CAH) are a group of heritable disorders associated with a deficiency in cortisol synthesis. The most common cause of CAH is a mutation in the adrenal 21-a-hydroxylase cytochrome P450 that converts progesterone to 17-hydroxyprogesterone. One of the serious complications is a salt wasting syndrome which results in large serum sodium losses. What effects on hormone levels would be expected? OA. ACTH is elevated and aldosterone is reduced OB. ACTH is reduced and aldosterone levels remain unchanged OC. Both ACTH and aldosterone levels are unchanged OD. ACTH is elevated and aldosterone is unchanged OE. ACTH is reduced and aldosterone is elevated
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