Q6.2: The enzyme active site provides an optimized physical and chemical microenvironment to lower the activation energy of a reaction and promote catalysis. Describe three catalytic reaction mechanisms used by enzymes and provide an example of each type using specific enzymes.
Catalysis and Enzymatic Reactions
Catalysis is the kind of chemical reaction in which the rate (speed) of a reaction is enhanced by the catalyst which is not consumed during the process of reaction and afterward it is removed when the catalyst is not used to make up the impurity in the product. The enzymatic reaction is the reaction that is catalyzed via enzymes.
Lock And Key Model
The lock-and-key model is used to describe the catalytic enzyme activity, based on the interaction between enzyme and substrate. This model considers the lock as an enzyme and the key as a substrate to explain this model. The concept of how a unique distinct key only can have the access to open a particular lock resembles how the specific substrate can only fit into the particular active site of the enzyme. This is significant in understanding the intermolecular interaction between proteins and plays a vital role in drug interaction.
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Enzyme Structure and Function
Q6.2: The enzyme active site provides an optimized physical and chemical microenvironment to lower the activation energy of a reaction and promote catalysis. Describe three catalytic reaction mechanisms used by enzymes and provide an example of each type using specific enzymes.
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