Protein phosphatase 1 (PP1) helps regulate cell division and is a possible drug target to treat certain types of cancer. The enzyme catalyzes the hydrolysis of a phosphate group from myelin basic protein (MBP). The activity ofPP1 was measured in the presence and absence of the inhibitor phosphatidic acid (PA).[MBP](mg-mL-¹)0.0100.0150.0250.050Vo without PA(nmol-mL-¹ min-¹)0.02090.03550.04190.0838Use the data in the table to construct a Lineweaver-Burk plot. What type of inhibitor is phosphatidic acid?UncompetitiveNoncompetitiveMixed inhibitionCompetitiveVo with PA(nmol-mL-¹ min-¹)0.003810.006200.009310.01400

Answered: Image /qna-images/answer/e8f06948-b6da-4005-8642-e92a01cad44c.jpg

Protein phosphatase 1 (PP1) helps regulate cell division and is a possible drug target to treat certain types of cancer. The enzyme catalyzes the hydrolysis of a phosphate group from myelin basic protein (MBP). The activity of PP1 was measured in the presence and absence of the inhibitor phosphatidic acid (PA). [MBP] (mg-mL-1) 0.010 0.015 0.025 0.050 Vo without PA (nmol-mL-¹ min-¹) Uncompetitive Noncompetitive Mixed inhibition Competitive 0.0209 0.0355 0.0419 0.0838 Vo with PA (nmol-ml-1.min-¹) 0.00381 Use the data in the table to construct a Lineweaver-Burk plot. What type of inhibitor is phosphatidic acid? 0.00620 0.00931 0.01400

Protein phosphatase 1 (PP1) helps regulate cell division and is a possible drug target to treat certain types of cancer. The enzyme catalyzes the hydrolysis of a phosphate group from myelin basic protein (MBP). The activity of PP1 was measured in the presence and absence of the inhibitor phosphatidic acid (PA). [MBP] (mg-mL-1) 0.010 0.015 0.025 0.050 Vo without PA (nmol-mL-¹ min-¹) Uncompetitive Noncompetitive Mixed inhibition Competitive 0.0209 0.0355 0.0419 0.0838 Vo with PA (nmol-ml-1.min-¹) 0.00381 Use the data in the table to construct a Lineweaver-Burk plot. What type of inhibitor is phosphatidic acid? 0.00620 0.00931 0.01400

Chemistry: The Molecular Science

5th Edition

ISBN:9781285199047

Author:John W. Moore, Conrad L. Stanitski

Publisher:John W. Moore, Conrad L. Stanitski

Chapter11: Chemical Kinetics: Rates Of Reactions

Section: Chapter Questions

Problem 83QRT

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