People having Raynauds syndrome are apt to suffer a sudden impairment of blood circulation in fingers and toes. In an experiment to study the extent of this impairment, each subject immersed a forefinger in water and the resulting heat output (cal/cm2/min) was measured. For m = 12 subjects with the syndrome, the average heat output was x = 0.64, and for n = 12 non-sufferers, the average output was 2.05. Let µ1 and µ2 denote the true average heat outputs for the two types of subjects. Assume that the two distributions of heat output are normal with σ1 = 0.2 and σ2 = 0.2. 1) Consider testing H0: µ1 − µ2 = 0 versus Ha: µ1 − µ2 < 0 at level 0.01. Describe in words what Ha says, and then carry out the test. 2) What is the probability of a type II error when the actual difference between µ1 and µ2 is µ1 − µ2 = −1.2? 3) Assuming that m=n, what sample sizes are required to ensure that β=0.1when µ1− µ2 = −1.2?

Calculus For The Life Sciences
2nd Edition
ISBN:9780321964038
Author:GREENWELL, Raymond N., RITCHEY, Nathan P., Lial, Margaret L.
Publisher:GREENWELL, Raymond N., RITCHEY, Nathan P., Lial, Margaret L.
Chapter8: Further Techniques And Applications Of Integration
Section8.EA: Extended Application Flow Systems
Problem 2EA
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People having Raynauds syndrome are apt to suffer a sudden impairment of blood circulation in fingers and toes. In an experiment to study the extent of this impairment, each subject immersed a forefinger in water and the resulting heat output (cal/cm2/min) was measured. For m = 12 subjects with the syndrome, the average heat output was x = 0.64, and for n = 12 non-sufferers, the average output was 2.05. Let µ1 and µ2 denote the true average heat outputs for the two types of subjects. Assume that the two distributions of heat output are normal with σ1 = 0.2 and σ2 = 0.2.

1) Consider testing H0: µ1 − µ2 = 0 versus Ha: µ1 − µ2 < 0 at level 0.01. Describe in words what Ha says, and then carry out the test.

2) What is the probability of a type II error when the actual difference between µ1 and µ2 is µ1 − µ2 = −1.2?

3) Assuming that m=n, what sample sizes are required to ensure that β=0.1when µ1− µ2 = −1.2?

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