You are analyzing a forensic sample for the presence of controlled substances using HPLC. Which ofthe following detectors would be the best one to use to confirm the identities of the substances inthe sample?UVevaporative light scatteringrefractive indexelectrochemicalMS Look at Figure below which represents a gas chromatogram obtained at 40° C. If youchromatographed the same sample at 25° C how would the chromatogram change?Detector responseSolvents1 15HO -K2,3-Dimethyl-2-butanol1-Butanol101151-Pentanol20125Time (min)the peaks would be closer togetherthe peaks would be larger in areathe peaks would be farther apart30the peaks would be smaller in area351-Hexanol^InjectionFigure 24-8 Chromatogram of alcohol mixture at 40°C using packed column(2 mm inner diameter x 76 cm long) containing 20% Carbowax 20M on Gas-Chrom Rsupport and flame ionization detector. [Courtesy Norman Pearson.)4045

You are analyzing a forensic sample for the presence of controlled substances using HPLC. Which of the following detectors would be the best one to use to confirm the identities of the substances in the sample? O UV evaporative light scattering refractive index electrochemical

You are analyzing a forensic sample for the presence of controlled substances using HPLC. Which of the following detectors would be the best one to use to confirm the identities of the substances in the sample? O UV evaporative light scattering refractive index electrochemical

Fundamentals Of Analytical Chemistry

9th Edition

ISBN:9781285640686

Author:Skoog

Publisher:Skoog

Chapter7: Statistical Data Treatment And Evaluation

Section: Chapter Questions

Problem 7.3QAP

See similar textbooks

Related questions

Q: "F ||| OCHEMICAL REACTIONS Balancing chemical equations with interfering coefficients Balance the…

A: (1) Label Each Compound With a Variable:- Label each compound (reactant or product) in the…

Q: What should be done before measuring an unknown pH of a solution using a pH meter

A: When measuring the pH of an unknown solution using a pH meter, it is important to follow certain…

Q: 8. Which of the following pairs lists the weaker acid first? a. НСІ. НСЮ b. HBrO4, HBrO3 c. H₂O,…

A: we have to select the pair in which weaker acid is written first

Q: Using an experimentally determined value (1.1×10-10) of K sp, determine the value for the reaction…

A: We know if Ionic product is more than solubility product then precipitate forms.if ionic product is…

Q: The radioactive isotope 133-54 Xe is used in pulmonary respiratory studies to image the blood flow…

A: We have radioactive isotope of Xe whose half life is 5 days. t12= 5 days t = 10 days. (time…

Q: NaOH is added to 0.040 M A1³+, raising the pH to 13.60. which is the predominant species: Al(OH)3 or…

A: strong base, such as NaOH, precipitates Al(OH)3, which is amphoteric and dissolves in an excess of…

Q: Part 2 - Colorimetric Representation of Le Chatlier's Principle Mass needed to make 15.0 mL of 0.200…

A: Molarity of CoCl2.6H2O solution=0.200 M Volume of solution=15.0 mL Molecular weight=237.93 g/mol

Q: Consider the following reaction at 298 K. 3Cr³+ (aq) + Cr(s) → 3Cr²+ (aq) + Cr³+ (aq) Which of the…

Q: The radioactive isotope 133-54 Xe is used in pulmonary respiratory studies to image the blood flow…

Q: What is the expected product of the following reaction? Br Pd(OAc)2 SnBu3

A: Palladium catalyzed reaction are mainly used for coupling reaction. Coupling reaction referred as…

Q: Use the standard reduction potentials located in the 'Tables' linked above to calculate the…

A: We know that

Q: Write the balanced NET IONIC equation for the reaction that occurs when ammonium chloride and sodium…

A: When ammonium chloride and sodium hydroxide are combined, they undergo a neutralization reaction to…

Q: HDPE and PS are both inert to bases and acids, which plastic would you rather chose to put 1 Liter…

A: HDPE is high density polyethylene is a thermoplastic made from many ethylene molecules and it is…

Q: ▼ Part B Determine the value of the rate constant. Express the rate constant to three significant…

A: Given N2O5 (g) -----> NO3 (g) + NO2 (g) And data of time and concentration of N2O5

Q: 9. Using curved-arrows, propose a mechanism for the following transformation and draw the major…

Q: Propose a reasonable mechanism for the following reaction. CI excess H₂NCH3 H

A: If the addition reaction is strated by the nucleophile then it's called as nucleophilic addition…

Q: Consider the reaction A + B = C+ D. Suppose you start with 1M A, 1M B, no C, and no D. What will…

A: The question is based on the concept of chemical equilibrium. we need to identify the effect on…

Q: O Macmillan Learning Write the Henderson-Hasselbalch equation for a propanoic acid solution…

Q: Provide the major organic product of the following reaction. { + AlCl3

A: The given reaction is shown below We have to draw the product of the given reaction.

Q: Na2O2 (s) + H₂O(1) → Express your answer as a chemical equation including phases. 0 ΑΣΦ ? A chemical…

Q: Using IUPAC guidelines, determine the name for the carboxylic acid shown below. OH CI (Hint: Pay…

A: • Identify the longest continuous carbon chain. • Identify the substituent group attached to the…

Q: Which of the following values best approximates the pKp value of the weak base? a. 9.8 b. 8.4 c. 7…

A: pKb can be calculated from a pH vs volume of titrant. For a monobasic acid half of the equivalence…

Q: Which substance would produce a melting point of -6.0°C in a 1000 gram solution of water? All given…

A: Depression in melting point is a colligative property observed in solutions when a solute is…

Q: ООО С CH3 d. 4 b. 2 C. 3 a. 1 HBr peroxides مة لا مل من Br 2 3 Br Br CH3 4 Br

A: The Anti-Markovnikov rule defines regiochemistry in which the substituent is attached to a less…

Q: Draw the mechanism for when tert-pentyl alcohol reacts with phenyl isocyanate. here's what was done…

A: Alcohols on reaction with phenyl isocyanate form carbamates.

Q: What is the pH of a solution with [OH-] = 1.8x10-5? a. 4.75 b. 9.25 C. 7.00

A: We have the concentration [OH-] = 1.8×10–5 We need to calculate the pH of this solution.

Q: Balance the following redox reactions by the half-reaction method: Cr(s) + N2H4(aq) = NH3(aq) +…

Q: Provide IUPAC name for the product of the following reaction: OH Type your answer and submit X₂ Xº…

Q: Curved arrows are used to illustrate the flow of electrons. Using the provided starting and product…

A: The given reaction scheme is shown below We have to draw the curved arrow pushing mechanism of the…

Q: When mixing a concentraitoin of 100 mL what glassware would be appropriate?

A: The question is based on the concept of experimental Chemistry . we need to identify the glassware…

Q: OH OH 3 different disconnections are possible 3 different disconnections are possible, do you see…

A: The question is based on the concept of organic synthesis. we need to synthesize the product using…

Q: Given that the positron is the antimatter equivalent of an electron, what is its approximate atomic…

A: Given that, Particle = positron Atomic mass of positron = ?

Q: Part 2 - Colorimetric Representation of Le Chatlier's Principle Mass needed to make 15.0 mL of 0.200…

A: Le Chatelier's principle states that changes in the system such as temperature, pressure, volume or…

Q: Calculate the pH during the titration of 150 mL of 0.17 M Benzoic acid(aq) with 0.34M NaOH(aq) –…

A: Given, 150 mL of 0.17 M Benzoic acid ( HC6H5CO2 )with 0.34M NaOH(aq) – after the following…

Q: how many 75.0 mg tablets should someone weight 148.2 Ibs take if the recommended dosage of…

Q: Sort these amines based on their solubility in water, as either soluble or not soluble using the…

A: A question based on solubility. 6 compounds are given that are to be distinguished based on their…

Q: Calculate the standard cell potential, ?∘cell, for the reaction shown. Use these standard reduction…

A: As per the standard data : E°Cu+ /Cu = 0.52 V E°Ag+ /Ag = 0.80 V

Q: nanging the temperature. 916040 =H₂(g) + Cl₂(g), Kc = 0.290 at 400 K. If 1.50x10³ M of HCL, H₂, and…

A: The question is based on the concept of Le-chatlier principle. It States that when a system at…

Q: The major product(s) of the following reaction is(are): H H H CH3 I O A. IV O C.I O D. II CH3 O E.…

Q: draw the mechanism for when tert-pentyl alcohol reacts with Jones' Oxidation test

A: The question is based on the concept of organic reactions and qualitative analysis . we need to…

Q: You will need to take logs and antilogs to solve many chemistry problems. For practice, complete the…

Q: 20

A: Bond order, which refers to the number of chemical bonds between a pair of atoms, shows how stable a…

Q: Name the following ester according to the IUPAC rules. CH3 CH₂-C-0-CH₂-CH3 3-pentanone O ethyl…

A: Dear student since you have posted multiple questions, As per BARTLEBY QnA guidelines we are allowed…

Q: For a particular reaction at 209.2 °C, AG = -521.63 kJ/mol, and AS = 963.23 J/(mol. K). Calculate AG…

A: The relation between Gibbs energy (G), enthalpy (H), entropy (S) and temperature (T) is: ∆G=∆H-T∆S…

Q: In condensed structural formulas, the amide group in an amide produced from a carboxylic acid and a…

A: Amide underogo hydrolysis with dil HCl to form carboxylic acid and ammonium salt.

Q: What is the value of K for this aqueous reaction at 298 K? K= A+B C + D 5.08 ×10² Incorrect AG =…

A: A + B ⇌ C + D Temperature (T) = 298 K Standard change in Gibbs free energy (∆G°) = 25.13 kJ/mol =…

Q: In the electrolysis of a molten mixture of RbF and CaCl2, identify the product that forms at the…

A: Anode is the electrode where the process of oxidation takes place. Cathode is the electrode where…

Q: Assume that the reaction below is at equilibrium. A stress is then applied as described. Click on…

A: Le Chatelier's principle: According to the Le Chatelier's principle when a change in concentration…

Q: Calculate the concentration of HS in an aqueous solution of 6.29x10-2 M hydrosulfuric acid, H₂S…

Q: Which of the following polymers can be used in a form of expanded foam: LDPE, HDPE, PP, Natural &…

A: Polymer- are the complex , large molecules (macromolecules) which are formed by joining small…

Concept explainers

Quantum Chemistry

Quantum chemistry deals with the properties of chemical systems and their reactions. The branch of chemistry which is more concerned with quantum chemistry is physical chemistry. It is a more sophisticated field of theoretical physics which is concerned towards the application of physical concepts towards various chemical aspects such as, formation of atoms, chemical structure descriptions, chemical bond strength, hybridization, conjugation etc. Quantum chemistry mainly studies the various states i.e., ground state, excited state, transition states of the individual atoms or molecules taking place during any chemical reaction. The laws of motion explained by various scientists, which are termed as “classical mechanics” were not acceptable in terms of electrons, protons, atoms, light etc. Thus, a new theory named “quantum mechanics” emerged to understand the basic framework of various atomic and subatomic particles.

Question

You are analyzing a forensic sample for the presence of controlled substances using HPLC. Which of
the following detectors would be the best one to use to confirm the identities of the substances in
the sample?
UV
evaporative light scattering
refractive index
electrochemical
MS

Look at Figure below which represents a gas chromatogram obtained at 40° C. If you
chromatographed the same sample at 25° C how would the chromatogram change?
Detector response
Solvents
1 1
5
HO -K
2,3-Dimethyl-2-butanol
1-Butanol
10
1
15
1-Pentanol
20
1
25
Time (min)
the peaks would be closer together
the peaks would be larger in area
the peaks would be farther apart
30
the peaks would be smaller in area
35
1-Hexanol
^
Injection
Figure 24-8 Chromatogram of alcohol mixture at 40°C using packed column
(2 mm inner diameter x 76 cm long) containing 20% Carbowax 20M on Gas-Chrom R
support and flame ionization detector. [Courtesy Norman Pearson.)
40
45

Expert Solution

This question has been solved!

Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.

This is a popular solution!

SEE SOLUTION Check out a sample Q&A here

Step 1: Answer

VIEW

Step 2: Solutions

VIEW

Solution

VIEW

Trending now

This is a popular solution!

Step by step

Solved in 3 steps

SEE SOLUTION Check out a sample Q&A here

Knowledge Booster

Introduction and Principles of Quantum Theory

Learn more about

Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemistry and related others by exploring similar questions and additional content below.

Similar questions

The methodology of choice for measuring therapeutic drug levels is Question 4 options: immunoassay chromatography atomic absorption spectrophotometry spectrophotometry
Describe the origin of shot noise in a spectrophotometer. How does the relativeuncertainty vary with concentration if shot noise is the major noise source?
3. The lead in a swab sample, lead standards, together with a blank were made up in 5.00 mL volumetric flasks using 0.2 % HNO3. 20 μL aliquots of these solutions were injected into the spectrophotometer and the absorbance measured at 217 nm. The following results were obtained. lead / ppb Absorbance 0 0.0591 10.00 0.0858 50.00 0.1926 100.0 0.3260 150.0 0.4594 200.0 0.5929 Swab sample 0.3700 (a) Determine the amount of lead in the swab sample in μg.
Can paper chromatography be used to separate and identify very volatile substances? Why? Please explain comprehensively.
10 Wavelength, 1. (nm) E (Red, µ.Mcm- ɛ(Yellow, µMr'cm¬1) Absorbance 500 0.0369 0.000549 0.405 430 0.00506 0.0167 0.474 An orange colored solution is prepared by mixing a red dye solution with a yellow dye solution and the absorbance was measured at the analytical wavelengths of 430 nm and 500 nm. The table provides the molar absorptivity for the red and yellow dye at each analytical wavelength. Calculate the concentration (in u.M) of the red and yellow dye in the mixture. [red] = [yellow] =
What are the 5 important characteristics of spectrophotometric methods
State True/False for the following statements. 1. In UV-Vis spectrophotometric analysis, the 2.82% transmittance of solution has an absorbance value of 1.55. 2. Peaks resulting transitions from n→ are shifted to shorter wavelengths (blue shift) with an increasing of solvent polarity. 3. In molecular absorption spectrophotometry, the relationship between transmittance and concentration is not linear while the absorbance vs concentration is linear. 4. Beer's Law states that absorbance of a compound is directly proportional to the log of the concentration of the absorbing species. 5. Different colors of the lights are refer to the waves with different amplitudes.
Which separation technique could be used to separate a mixture based on differnces in boiling point. O filtration O distillation O chromatography 10 11 12 13 5
In the process of performing a spectrophotometric determination of Fe, an analyst prepares a calibration curve using a single-beam spectrometer, such as a Spec-20. After preparing the calibration curve, the analyst drops the cuvette used for the method blank and the standards. The analyst acquires a new cuvette, measures the absorbance of the sample, and determines the %w/w Fe in the sample. Will the change in cuvette lead to a determinate error in the analysis? Explain.
A solution of a dye was analyzed by spectrophotometry, and the following calibration data were collected using a 1 cm cuvette. *graph in attachemnt* Using the calibration data above for the dye solution, what is the dye concentration in a solution with an absorbance (A) = 0.52 if it was measured in a 1 cm cuvette? Group of answer choices 3.0 x 10-6 M 6.0 x 104 M 2.0 x 10-6 M Not enough information is provided.
For the determination of Fe3 +, 25 mL of sample taken from sea water is diluted to 100 mL and a quantity of the obtained solution is taken and Fe3 + is determined by atomic absorption spectrophotometer. The absorbance values of the standard and sample solutions are below, and calculate the Fe3 + concentration in sea water in mg / L by drawing the relevant graph.Solution Absorbance1 mg / L Fe3 + 0.04095 mg / L Fe3 + 0.205110 mg / L Fe3 + 0.411615 mg / L Fe3 + 0.620820 mg / L Fe3 + 0.8222Sample Solution 0.5155
To test a spectrophotometer’s accuracy, a solution of 60.06 ppm K2Cr2O7 is prepared and analyzed. This solution has an expected absorbance of 0.641 at 350.0 nm. Several aliquots of the solution produce the following absorbance values. 0.640    0.638    0.640    0.639    0.640    0.639    0.638 is there any significant difference between the experimental mean and the expected value at a 99.9% confidence level? Question 21 options: Yes because tcal<tcritical Yes because tcal>tcritical No because tcal<tcritical No because tcal>tcritical