kąk4 k2k1 E +S → ES → E + P (Vmax,f\ rax.f (Vmax,b [P] KM.f KM.b [S] [P] Vo 1+ KM.f Кмь KM,b ||

Case Studies In Health Information Management
3rd Edition
ISBN:9781337676908
Author:SCHNERING
Publisher:SCHNERING
Chapter7: Healthcare Statistics And Research Methods
Section: Chapter Questions
Problem 7.33.4C
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In enzyme kinetics, for the reversible with one complex mechanism, please provide complete proof that the rate equation is the equation below. The variables denoted with f indicates forward direction while the variables denoted with b indicate backward direction.

k2k1
E + S → ES → E + P
k4k4
E + P
Vmax.f
KM.f
[S] –
[S] , [P]
(Vmax,b
KM.b
[P]
+
KM.f
KM.b
1+
||
Transcribed Image Text:k2k1 E + S → ES → E + P k4k4 E + P Vmax.f KM.f [S] – [S] , [P] (Vmax,b KM.b [P] + KM.f KM.b 1+ ||
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