Is it expected that a change in the primary, in the secondary or in the tertiary structure of a protein will produce more functional consequences?
Q: Draw the structure of the amino acid arginine and indicate all ionizable groups
A: Proteins are unbranched polymers constructed from 20 standard α-amino acids. They have four…
Q: How can the phosphorylation of a protein result in conformational changes?
A: Phosphorylation generally alters the structural as well as functionality of protein. It alters the…
Q: Once modified, do proteins always have the correct threedimensional structure?
A: Protein modification is important to attain the specific shape of the protein, which is crucial for…
Q: Explain why a change in the primary structure of a protein may alter the tertiary structures. Give…
A: The main structure of a protein is the sequence of amino acids in peptides or proteins. In…
Q: If an oligosaccharide is attached to a protein via an O-glycosidic linkage which amino acid…
A: The glycoproteins are formed by the joining of oligosaccharide with protein. The glycoproteins are…
Q: How Is the Primary Structure of a ProteinDetermined?
A: The proteins are synthesized from the mRNA which carries the genetic information of the DNA. These…
Q: How might mutation result in a change in the primary structure of a protein?
A: The mutation is a variation in the nucleotide sequence of the genetic material of an organism.
Q: What if the protein does not have a primary structure, what is its implication? Explain and give…
A: The primary structure refers to the amino acid sequence of a protein. The primary structure is…
Q: What are the structural characteristics common to all amino acids found in naturally occurring…
A: Amino acids are the building blocks of proteins, Alpha carbon of amino acids contains, carboxyl…
Q: What is the highest structural level of protein structure represented in the following image?…
A: When applied to proteins, the term structure has a far more complicated meaning than when applied to…
Q: How does the structure of the protein in the aggregated form differ from that of the protein in its…
A: The protein which is responsible for the neuro-degenerative disease is PrPpc (prion protein).
Q: What forces stabilize the quaternary structure of a protein?
A: The spatial arrangement of several tertiary structures forms the quaternary structure. Subunits,…
Q: Describe the basic general structure of an l-a-amino acid,and draw its structure
A: Amino acids are the building blocks of protein. where they are 20 standard amino acids that code for…
Q: Which amino acid sequence is likely to be found on the exterior of a soluble protein?
A: Proteins are polymers of amino acids linked by amide/peptide bonds. Amino acids are consist of amine…
Q: In sickle cell anemia, a hereditary disease, there is substitution of one amino acid by another in…
A: Sickle cell disease is a blood condition that is most commonly found in the people of African…
Q: The three-dimensional structure of a protein is determined by its primary, secondary, and tertiary…
A: The order of arrangement of amino acids in the peptides is called as Primary structure. The…
Q: What is protein denaturation? Is there any change in the primary structure when a protein is…
A: Proteins are the molecular tools, which perform an astonishing variety of functions. Moreover to…
Q: Which of the following amino acids is most likely to be found on the outside of a soluble protein,…
A: (a) Valine is most likely to be found in the inside of the protein. Since valine contains a non…
Q: Why is hydrolysis of a protein not considered to be denaturation?
A: Hydrolysis is a chemical process in which a molecule of water is added to a substance. Sometimes…
Q: What is the importance of each protein structure (Primary, Secondary, Tertiary, and Quaternary…
A: Amino acids are defined as the organic monomer molecules where they act as the functional building…
Q: If a Cys residue in a protein was replaced with either Ser or Phe amino acid, which substitution…
A: Amino acids Proteins are the polymers of nitrogenous compounds called amino acids. Each amino acid…
Q: Which of the following best describes an amino acid that can be used to synthesize proteins?
A: Monoprotic acids - are the acids that donates only one proton (H atom) per molecule of acid to an…
Q: Why is the exact order of amino acids (primary structure) in a protein important?
A: Amino Acids : Amino acids are organic compounds that combine to form proteins. Amino acids and…
Q: Which protein structure is due to interactions between amino acid side-chains? tertiary, quaternary,…
A: The structure of proteins have four levels of structure called the primary, secondary, tertiary and…
Q: a. Any given protein is characterized by a unique amino acid sequence (primary structure) and three…
A: Proteins are biopolymers made of amino acids as monomeric units. The amino acid consists of an amine…
Q: Would the peptide group be planar if the amino group of amino acids was bonded to the β carbon of…
A: Peptide group is generally linked to the amide bond that links the α-amino nitrogen of one amino…
Q: How does the amino acid sequence of a protein specify its threedimensional structure?
A: Protein structure is the three dimensional arrangement of atoms in an amino acid chain. Proteins are…
Q: Are proteins with the same number of each different amino acid that form them necessarily identical…
A: Proteins are made up of a long chain of amino acids that are joined together by peptide bonds. They…
Q: Why is it important to specify the three-dimensional structure of amino acids?
A: Amino acids are the biomolecules that act as a polymer for the synthesis of protein and these are…
Q: Why is cysteine such an important amino acid for defining the tertiary structure of some proteins?
A: Protein has several confirmation levels, out of which quaternary level is the most functional…
Q: The base sequence of which type of RNA is responsiblefor determining the order of amino acids in a…
A: Translation is the mechanism by which ribosomes in the cytoplasm or endoplasmic reticulum synthesize…
Q: For the amino acids listed below, what tertiary/quaternary interaction can each of the amino acids…
A: Tertiary structure is the three dimensional conformation of a protein. Proteins with more than one…
Q: What primarily determines the secondary and tertiary structures of a protein?
A: A single protein molecule consists of one or more of protein structure types: primary, secondary,…
Q: What is the tertiary structure of a protein? What are the main types of tertiary structure?
A: Proteins are the large size macromolecules that are formed by the polymers of amino acids,…
Q: Explain how the tertiary structure of a protein is stabilized by various intermolecular forces and…
A: A protein is considered to be a biological macromolecule made up of one or more polypeptide…
Q: Why is the 3-Dimensional structure important for protein function?
A: “Since you have asked multiple questions, we will solve the first question for you. If you want any…
Q: Name another condition besides heat and exposure to a bond disruptor (like alcohol) that could…
A: Proteins are polymers that are made up of monomers called amino acids. An amino acid has a central…
Q: Can a mutation change a protein’s tertiary structure without changing its primary structure? Explain…
A: Every function in living beings depends on proteins. There are different types of proteins and each…
Q: How many different molecules composed of (a) two, (b) three, and (c) four amino acids, linked…
A: Proteins are the polypeptide chain of amino acids that are held together by the peptide bonds. These…
Q: What drives spontaneous folding into the correct tertiary structure for a newly synthesized protein?
A: Proteins are made up of amino acid residues held together by peptide bonds. A protein reversibly…
Q: Which of the following correctly describes a typical alpha helix protein secondary structure?
A: Protein play wide variety of essential function in our body. They provide strength and structural…
Q: which amino acid can form a covalent bond with its side chain? b. which amino acid can contribute to…
A: Proteins are polypeptide structures that comprise of amino acids. Proteins are synthesized from the…
Q: Draw the generalized structure of an amino acid, and a peptidebond that connects them in proteins
A: Amino acids are the molecules that combines to a protein.In amino acid centrally placed carbon atom…
Q: What are intrinsically disordered proteins ? What are their features in terms of amino acid…
A: Proteins are biomolecules composed of amino acids. Amino acids are joined together through peptide…
Q: How does the primary structure of a protein corresponds to the linear order of amino acids in a…
A: Proteins are composed of amino acids. Natural proteins which get synthesized inside the cells are…
Is it expected that a change in the primary, in the secondary or in the tertiary structure of a protein will produce more functional consequences?
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- Refer to the figure below. Replacing lysine with another amino acid in the protein may alter the shape and function of the protein. Replacing lysine with which type(s) of amino acid(s) would lead to the least amount of change in the tertiary structure of this protein? Explain.Which of the following statements best describes the hydrophobic character of bacteriorhodopsin (2BRD)? Both the interior and exterior of the protein are hydrophobic, including the central core of the trimer. Both the interior and exterior of the protein are hydrophilic, including the central core of the trimer. Both the interior and exterior of the protein are hydrophilic, but the central core of the trimer is hydrophobic. Both the interior and exterior of the protein are hydrophobic, but the central core of the trimer is hydrophilic.HOW MANY DIFFERENT PROTEINS CAN BE CONSTRUCTED THAT ARE EXACTLY FOUR AMINO ACIDS LONG? (HINT: THERE ARE 20 POSSIBLE AMINO ACIDS.)
- In the amino acid sequence below, the amino acid residue in red was shown to be essential to the function of the protein. .VAIALWLIFWFIISVGGIY. If this residue was to be replaced by another, which of the following replacements would most likely lead to an abrogation of the protein's function? OL O E OG O AWhat general structural feature is shared by proteins that specifically form homodimers (but not homotrimers, homoteramers etc)? Only one answer is correct. the surface consists of hydrophilic alpha-helix. the surface is highly modified by post-translational modification. the surface is permanently bound by chaperones. the surface is unstructured. the surface, or part of it, is self-complementary.What type of intramolecular interactions can be found between amino acids within proteins to help maintain their native structure?
- I was given an amino acid position 564 with the PDC code 2V1X. Would it be possible to describe why this position in the protein is important and outline the effects the mutation will have on the structure / function of the protein? Thank you.Explain how polypeptides are arranged to form the primary, secondary and tertiary structure of a protein how mutations can cause a change in the sequence of amino acids of a polypeptide? Compare the effects of addition/ deletion mutations and substitution mutationsProper folding is essential for most proteins to function. Which of the following statement about protein folding are correct. There may be more than 1 right answer. a) changing the primary sequence will change the final conformation b) desaturation results in a protein that has a higher free energy than the native conformation c) protein spontaneously fold into their correct shape d) denatrutation will cause a protein to lose its tertiary structure
- In N-linked glycoproteins, the sugar is usually attached to the protein by a bond to the N atom in a side-chain amide. Which amino acids can form such a bond?d) Describe what is meant by the primary structure of a protein? e) At the secondary level of structure, protein molecules will fold in either of two ways. • What are these two secondary forms of folding called? • What do these two forms look like structurally? • How is their structural arrangement stabilised? f) Describe the tertiary structure of a protein. g) Describe the biological function of the peptide hormone insulin. h) Haemoglobin is an example of a quaternary protein. Briefly describe the structure of this protein and state its biological function. Part 2 Monosaccharides and disaccharides are two of the sub-classes of Carbohydrates. Structure B shown below is a specific example of a monosaccharide. H HO Structure B CH₂OH H OH H OH H OH a) Name Structure B and describe its function within cells. b) State the name of a disaccharide that contains this molecule (Structure B) and describe its structure. c) A branched polysaccharide made up of many monomers of Structure B bonded…d) Describe what is meant by the primary structure of a protein? e) At the secondary level of structure, protein molecules will fold in either of two ways. • What are these two secondary forms of folding called? • What do these two forms look like structurally? • How is their structural arrangement stabilised? f) Describe the tertiary structure of a protein. g) Describe the biological function of the peptide hormone insulin. h) Haemoglobin is an example of a quaternary protein. Briefly describe the structure of this protein and state its biological function.