In your own words, explain each of the hallmarks of cancer. (immortality, produce go signals, override stop signals, resist cell death, angiogenesis and how it relates to metastasis.
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In your own words, explain each of the hallmarks of cancer. (immortality, produce go signals, override stop signals, resist cell death, angiogenesis and how it relates to metastasis.
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- In your own words, what is angiogenesis and what is the importance of this process in cancer progression?The one of the “hallmarks of cancer" cells is they retain their ability to regulate the cell cycle. True FalseT/F: Only a small fraction of cancer cells successfully metastasize. why is it false or why is it true.
- Out of these 8 hallmarks ( sustaining proliferative signaling, evading growth suppressors, resisting cell death, enabling replicative immortality, inducing angiogenesis, activating invasion and metastasis, deregulating cellular energetics and metabolism, and avoiding immune destruction). Rank them from least important to most for cancer development. Explain in 2-3 sentences how.Excessive angiogenesis and reduced apoptosis are two of the six characteristics that define cancerous tumors. Discuss how developing treatments for these two conditions might prevent the development of cancer altogether from pre-malignant tumors.There are many types of cancer. What do all types of cancer have in common
- What the hallmarks of cancer are? and briefly explain two of them.In your own words, explain how cancer cells differ from normal cells in regard to the following: ApoptosisDespite all that we know about cancer today, some types of cancers are still increasing in frequency. Lung cancer among nonsmoking women is one of these. What reason(s) might there be for this increasing problem?
- #1) Hyperplastic growth are not cancerous yet but show a higher than normal proliferation rate. True False #2) When cancer cells have not spread beyond its original site, the term used to describe it is benign growth intraepithelial neoplasia carcinoma stage 3 carcinoma in situ #9) Cancer cells generally have missense mutations in p53 gene, resulting in truncated p53 normally active p53 dominant negative p53 inactive p53 #10) Single or double stranded breaks in DNA activate Chk 1 and 2 kinases, which phosphorylates p53. This results in --- in the level of p53 in the cell. increase decreaseAlthough cancer is not a contagious disease in humans or other vertebrates, there have been rare cases in which cancers have spread from one organism to another. Describe three cases of these contagious cancers and what conditions might have led to their appearance. For an introduction to this topic, see http:// www.cancer.org/cancer/cancerbasics/is-cancer-contagious.Cells can become cancerous for many reasons. Regardless of how they become cancerous, the same general pattern is followed. Put the steps of cancer development in order from first to last. 1. A cell begins to grow and divide uncontrollably.2. The cell metastasizes and moves through the bloodstream, spreading throughout the body.3. Part of the tumor breaks off and is now malignant.4. The benign tumor is confined to one place.5. A small mass forms, called a tumor.