In this case a family history revealed a genetic basis for the disorder. The pedigree is shown in Fig. 1 Below. Key Ø Female: affected Female: unaffected I IV V 김마 7800 9 10 10 머 Male: affected Male: unaffected Deceased Disease status not given Dizygotic twins Monozygotic twins Fig. 1 Disease pedigree. Five generations I, II, III, IV, V are shown. Females are represented by circles, males by squares, dizygotic (non-identical) twins by diagonal lines originating from the same point, Monozygotic (identical) twins by diagonal lines originating from the same point and joined symbols and deceased by a diagonal line through the symbol. Filled symbols indicate that the individual displays the disease phenotype. Unfilled symbols indicate that the individual does not display the disease phenotype. Carriers of the disease are not indicated. Information on disease status is not known for generation I and is omitted for the individuals represented by a symbol with an asterisk. The person referred to in the opening paragraph above is V.1. Consider which pattern(s) of Mendelian inheritance is (are) suggested by this pedigree and then answer questions 4-6 O a. It is expected that neither V.4 or V.5 would have the disease b. It is not possible to say what the disease status of V.4 or V.5 would be O c. It is expected that both V.4 and V.5 would have the disease O d. V.4 will not have the disease if his brother does not e. V.4 cannot have the disease as his mother is unaffected Question 6) Based on your deduced mode of inheritance and observations of the pedigree, which of the following statements about the most likely disease status of individuals V.4 and V.5 (not given in Fig. 1) is CORRECT?
In this case a family history revealed a genetic basis for the disorder. The pedigree is shown in Fig. 1 Below. Key Ø Female: affected Female: unaffected I IV V 김마 7800 9 10 10 머 Male: affected Male: unaffected Deceased Disease status not given Dizygotic twins Monozygotic twins Fig. 1 Disease pedigree. Five generations I, II, III, IV, V are shown. Females are represented by circles, males by squares, dizygotic (non-identical) twins by diagonal lines originating from the same point, Monozygotic (identical) twins by diagonal lines originating from the same point and joined symbols and deceased by a diagonal line through the symbol. Filled symbols indicate that the individual displays the disease phenotype. Unfilled symbols indicate that the individual does not display the disease phenotype. Carriers of the disease are not indicated. Information on disease status is not known for generation I and is omitted for the individuals represented by a symbol with an asterisk. The person referred to in the opening paragraph above is V.1. Consider which pattern(s) of Mendelian inheritance is (are) suggested by this pedigree and then answer questions 4-6 O a. It is expected that neither V.4 or V.5 would have the disease b. It is not possible to say what the disease status of V.4 or V.5 would be O c. It is expected that both V.4 and V.5 would have the disease O d. V.4 will not have the disease if his brother does not e. V.4 cannot have the disease as his mother is unaffected Question 6) Based on your deduced mode of inheritance and observations of the pedigree, which of the following statements about the most likely disease status of individuals V.4 and V.5 (not given in Fig. 1) is CORRECT?
Human Biology (MindTap Course List)
11th Edition
ISBN:9781305112100
Author:Cecie Starr, Beverly McMillan
Publisher:Cecie Starr, Beverly McMillan
Chapter19: Introduction To Genetics
Section: Chapter Questions
Problem 9CT
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