Imines are electrophiles in the related Mannich reaction. Draw two transition states, one leading to the syn diastereomer and one leading to the anti. Briefly explain which is favoured and why. Assume the imine doesn't change geometry.
Imines are electrophiles in the related Mannich reaction. Draw two transition states, one leading to the syn diastereomer and one leading to the anti. Briefly explain which is favoured and why. Assume the imine doesn't change geometry.
Organic Chemistry: A Guided Inquiry
2nd Edition
ISBN:9780618974122
Author:Andrei Straumanis
Publisher:Andrei Straumanis
Chapter13: Substitution
Section: Chapter Questions
Problem 4E
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![Imines are electrophiles in the related Mannich reaction. Draw two transition states, one leading to the syn
diastereomer and one leading to the anti. Briefly explain which is favoured and why. Assume the imine doesn't
change geometry.
OM
H3G
CH3
Ph
CH3](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Fef77b65a-2c5d-4829-8be9-ff060471b923%2F3357e99d-cef9-48ee-84a0-b71eeb1fc3ad%2Fmfhohp_processed.jpeg&w=3840&q=75)
Transcribed Image Text:Imines are electrophiles in the related Mannich reaction. Draw two transition states, one leading to the syn
diastereomer and one leading to the anti. Briefly explain which is favoured and why. Assume the imine doesn't
change geometry.
OM
H3G
CH3
Ph
CH3
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