If I put 10 mM ACh in the external solution instead of 2 mM, which of the following wo happen? O The channel would be open for more of the time O The ACh channel would pass more current when it is open none of the other choices are correct.

Human Anatomy & Physiology (11th Edition)
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(A) Patch clamp measurement of single ACh receptor current
Micropipette
ACh
I (PA)
2
O
2 mM Acetylcholine (ACh)
0
0
100 0
Na
2
4
Outside-out
membrane patch
ACh receptor
6
8
Time (ms)
10
12
none of the other choices are correct.
The channel would inactivate
Channel closed
If I put 10 mM ACh in the external solution instead of 2 mM, which of the following would
happen?
Channel open
The channel would be open for more of the time
The ACh channel would pass more current when it is open
Transcribed Image Text:(A) Patch clamp measurement of single ACh receptor current Micropipette ACh I (PA) 2 O 2 mM Acetylcholine (ACh) 0 0 100 0 Na 2 4 Outside-out membrane patch ACh receptor 6 8 Time (ms) 10 12 none of the other choices are correct. The channel would inactivate Channel closed If I put 10 mM ACh in the external solution instead of 2 mM, which of the following would happen? Channel open The channel would be open for more of the time The ACh channel would pass more current when it is open
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