Identify the infection (X) and provide a detailed description of the causative agent. (10) 2.2 Discuss the transmission and pathogenesis of the virus that causes infection X. (10) 2.3 Explain the clinical symptoms and laboratory diagnosis of infection X. (10) 2.4 Discuss the importance of vaccination
X is a zoonotic infection first identified in humans in 1970 in the Democratic Republic of Congo. The
infection presents clinically with fever, rash and swollen lymph nodes and may lead to a range of
medical complications. X was first identified outside of Africa in 2003 and later reported in the United
States of America, linked to contact with infected pet prairie dogs. The pets were reportedly housed
with Gambian pouched rats and dormice, imported from Ghana. X has also been further reported in
travelers from Nigeria to different countries around the world between 2018 and 2021. This resulted in
multiple cases of X identified in several non-endemic countries in 2022, including South Africa.
2.1 Identify the infection (X) and provide a detailed description of the causative agent. (10)
2.2 Discuss the transmission and pathogenesis of the virus that causes infection X. (10)
2.3 Explain the clinical symptoms and laboratory diagnosis of infection X. (10)
2.4 Discuss the importance of vaccination and management of secondary infections during
an outbreak of a viral infection.
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