ehmet Yavuz is 62 yo. He presented to the clinic and after having an HbA1c test (result 9%) was diagnosed with type 2 Diabetes mellitus. His cardiovascular risk was > 15%  http://www.cvdcheck.org.au/ His renal health screen showed an eGFR 90 mL/min/1.73m2 with microalbuminuria of 3.5 mg/mmol.   http://www.kidney.org.au/HealthProfessionals/DetectingCKD/tabid/632/Default.aspx He attended a podiatry appointment which detected decreased dorsalis pedis and posterior tibialis pulses in both legs.  Management of his condition now includes the following: Exercise: at least 150 minutes of aerobic and 60 minutes of resistance exercise each week Diet: a plan worked out with an accredited dietician based on the Australian Dietary Guidelines (2013). Drug use: smoking cessation plan to stop cigarette use; alcohol consumption reduction to 1 - 2 full strength beers every second day Weight loss: Mehmet aims to lose 5 kg over the first 6 - 8 weeks after diagnosis Medications: Jardiamet (empagliflozin 5mg, metformin 500 mg), twice daily, with or after food ramipril 5 mg, daily Rosuzet (rosuvastatin 20mg, ezetimibe 10mg), daily Ongoing diagnostics: HbA1c: every 3 months

Curren'S Math For Meds: Dosages & Sol
11th Edition
ISBN:9781305143531
Author:CURREN
Publisher:CURREN
Chapter13: Dimensional Analysis/units Conversion
Section: Chapter Questions
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Mehmet Yavuz is 62 yo. He presented to the clinic and after having an HbA1c test (result 9%) was diagnosed with type 2 Diabetes mellitus.

His cardiovascular risk was > 15%  http://www.cvdcheck.org.au/

His renal health screen showed an eGFR 90 mL/min/1.73m2 with microalbuminuria of 3.5 mg/mmol.  

http://www.kidney.org.au/HealthProfessionals/DetectingCKD/tabid/632/Default.aspx

He attended a podiatry appointment which detected decreased dorsalis pedis and posterior tibialis pulses in both legs.

 Management of his condition now includes the following:

  1. Exercise: at least 150 minutes of aerobic and 60 minutes of resistance exercise each week
  2. Diet: a plan worked out with an accredited dietician based on the Australian Dietary Guidelines (2013).
  3. Drug use: smoking cessation plan to stop cigarette use; alcohol consumption reduction to 1 - 2 full strength beers every second day
  4. Weight loss: Mehmet aims to lose 5 kg over the first 6 - 8 weeks after diagnosis

Medications:

  1. Jardiamet (empagliflozin 5mg, metformin 500 mg), twice daily, with or after food
  2. ramipril 5 mg, daily
  3. Rosuzet (rosuvastatin 20mg, ezetimibe 10mg), daily

Ongoing diagnostics:

  1. HbA1c: every 3 months
  2. lipid profile: every 3 months
  3. renal function assessment: annually
  4. podiatrist assessment: at least once a year
  5. optometrist assessment: at least once a year

question:

relate metformin therapy to Mehmet's pathophysiological presentation in brief.

  •  

 

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Follow-up Question
  1. From this list choose TWO (2)therapies to discuss:
  • empagliflozin
  • metformin
  • rosuvastatin
  • ramipril

You need to do the following for each medication:

  •  
    • describe the mechanism of ACTION/S 
    • identify the AIM of each therapy for Mehmet
    • relate each therapy to Mehmet's pathophysiological presentation
    • refer briefly to any GUIDELINES which support the use of each medication
    • identify one RISK or special consideration for Mehmet whilst taking each medication
    • identify what evidence will demonstrate the EFFECTIVENESS of each therapy if you were evaluating care provided to Mehmet
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